Clinical trials: Chronic Nephropathy
End Stage Renal Disease (ESRD), Peritoneal Dialysis Complication
The Effect of Exercise on Low Back Pain in Peritoneal Dialysis Patients
The goal of this randomized controlled trial is to find out if exercise can help reduce low back pain and improve quality of life in people receiving peritoneal dialysis (PD).
- Trial name
- NCT07000006
- Testing
- Home-based Core Stability Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Hemodialysis, ESRD
Comparison of Different Glucose Concentrations in Dialysate of Hemodialysis Patients
This study aims to show that using a glucose (sugar) concentration of 100 mg/dL in the dialysis fluid for hemodialysis is not inferior to using a concentration of 200 mg/dL with regard to the frequency and magnitude of blood…
- Trial name
- Dextrose (NCT00618033)
- Testing
- Hemodialysis
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Renal Research Institute
Chronic Kidney Disease, Chronic Periodontitis, Generalized, Moderate
Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant
The study aims to understand why dental infections in end-stage kidney patients results in poor outcomes for kidney functions and eventually transplant.
- Trial name
- NCT04020458
- Testing
- dental intervention
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Augusta University
Intradialytic Hypertension, End Stage Kidney Disease
Effect of Low Versus Standard Dialysate Sodium on 48h Ambulatory BP in Patients With Intradialytic Hypertension
Intradialytic hypertension (IDH) is a well-recognized and established complication of hemodialysis that affects an estimated 10-15% of the dialysis population and is associated with an increased risk for cardiovascular adverse…
- Trial name
- NCT05430438
- Testing
- dialysis with low dialysate sodium concentration, dialysis with standard dialysate sodium concentration
- Where
- 4 sites in Greece, Slovenia
- Volunteers
- 30 people
- Sponsor
- Aristotle University Of Thessaloniki
Kidney Diseases, Renal Insufficiency, Chronic
Sodium Intake in Chronic Kidney Disease (STICK)
Chronic kidney disease, which affects an estimated 300,000 people in Ireland and over 50 million people in the developed world, is responsible for a considerable burden of premature mortality and morbidity.
- Conditions
- Kidney Diseases, Renal Insufficiency, Chronic, Renal Insufficiency
- Trial name
- STICK (NCT02458248)
- Testing
- Sodium Reduction
- Where
- Ireland
- Volunteers
- 105 people
- Sponsor
- University College Hospital Galway
Diabetic Kidney Disease, Type 2 Diabetes
Development and Validation of a Machine Learning Model for Differentiating Diabetic Kidney Disease and Non-Diabetic Kidney Disease in Type 2 Diabetes
This multicenter retrospective observational study aims to develop and validate an interpretable machine learning model for differentiating diabetic kidney disease (DKD) from non-diabetic kidney disease (NDKD) in patients with…
- Conditions
- Diabetic Kidney Disease, Type 2 Diabetes, Chronic Kidney Disease
- Trial name
- NCT07672639
- Where
- China
- Volunteers
- 2,201 people
- Sponsor
- Beijing Tongren Hospital
Kidney Diseases, Metabolic Acidosis
Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
The goal of this clinical trial is to learn about and test the effect of an acid/base diet, in chronic kidney patients with CKD stage 4 and 5 in an interventional study with a historical control.
- Conditions
- Kidney Diseases, Metabolic Acidosis, Renal Insufficiency, CKD
- Trial name
- REMA-CKD (NCT05970094)
- Testing
- Low PRAL
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Copenhagen
End-stage Renal Disease, Depression
Feasibility RCT of ACT Self-help for Depression in Haemodialysis
The purpose of this study is to assess the feasibility of conducting a trial to evaluate a self-help treatment for depression in people with end-stage renal disease.
- Trial name
- NCT02565056
- Testing
- Self help book + telephone support
- Where
- 3 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Lincoln
Chronic Kidney Disease on Hemodialysis
The Self-management Program on Hemodialysis Patients in Cambodia
Chronic kidney disease (CKD) is a growing global health issue, with increasing numbers of patients requiring kidney replacement therapy (KRT), particularly in low- and middle-income countries.
- Trial name
- NCT06871553
- Testing
- Self management education program
- Where
- Cambodia
- Volunteers
- 45 people
- Sponsor
- Hiroshima University
Chronic Renal Failure, Hemodialysis
Efficacy of Intravenous Iron Administration in Hemodialysis Patients
The purpose of this study is to determine whether the frequency of intravenous iron administration has an effect on anemia correction and oxidative stress formation in hemodialysis patients.
- Conditions
- Chronic Renal Failure, Hemodialysis, Renal Anemia, Iron Deficiency Anemia
- Trial name
- NCT00298441
- Testing
- chondroitin sulfate-iron colloid
- Where
- 2 sites in Japan
- Volunteers
- 50 people
- Sponsor
- Kumamoto University
ESRD (End Stage Renal Disease)
Fluid Status of Dialysis Subjects
The goal of this clinical pilot study is to evaluate the ability of the device to properly detect the hydration status of the subject through the study of fluid removal data during dialysis and HemoCept device data.
- Trial name
- NCT07217041
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- HemoCept Inc.
ESRD
Ellipsys Fistula for Hemodialysis Access
To report the outcomes of patients having percutaneous proximal radial artery fistula creation.
- Trial name
- NCT03828253
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Richmond Vascular Center
Arterial Stiffness
Arterial Stiffness in Heart Failure and Chronic Kidney Disease
This observational study is assessing the effects that arterial stiffness may have on patients with heart failure (HF) and chronic kidney disease (CKD). Arterial stiffness will be measured by assessing pulse wave velocity (PWV).
- Trial name
- ASHFCKD (NCT05012722)
- Testing
- Sphygmocor CVMS (Atocr Medical, Sydney Australia) PWV measurement
- Where
- United Kingdom
- Volunteers
- 119 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Chronic Kidney Disease Associated Anemia
Correction of Anemia With Enarodustat in Non-dialysis Dependent Chronic Kidney Disease
The CANNON trial is a prospective, open-label, randomized, multicenter study designed to investigate rational hemoglobin target value in patients with anemia of non-dialysis chronic kidney disease treated with enarodustat.
- Trial name
- CANNON (NCT06725810)
- Testing
- Enarodustat
- Where
- China
- Volunteers
- 1,670 people
- Sponsor
- Shanghai Zhongshan Hospital
Chronic Kidney Disease and Hypertension
A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.
- Trial name
- NCT06268873
- Testing
- Baxdrostat/dapagliflozin
- Where
- 565 sites in United States, Argentina and 36 more
- Volunteers
- 2,554 people
- Sponsor
- AstraZeneca
Nephrogenic Systemic Fibrosis, Renal Failure
Nephrogenic Systemic Fibrosis With Gadollinum
Recently there is increasing reports of NEPHROGENIIC SYSTEMIC FIBROSIS(NSF) in patients with severe renal failure mainly in patients under dialysis in whom gadollinum is being used.
- Trial name
- NSF (NCT01359345)
- Testing
- gadollinum
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Imam Khomeini Hospital
Chronic Kidney Diseases
Assessment of Renal Vasculature and Function with Ferumoxytol-enhanced Magnetic Resonance Imaging
Conventional contrast-enhanced magnetic resonance imaging is typically performed with extracellular gadolinium chelates, which is often limited in patients with CKD owing to the risk of nephrogenic systemic fibrosis.
- Trial name
- NCT05045872
- Testing
- domestic polysaccharide superparamagnetic iron oxide nanoparticle
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Chronic Kidney Diseases
Effects of a Whole-food, Plant-based Nutrition Program on BP and Potassium in Subjects With CKD
The purpose of this study is to determine if an educational program emphasizing a whole food plant based diet favorably impacts blood pressure while not significantly increasing blood potassium levels, by comparing a group of…
- Trial name
- NCT06343129
- Testing
- Dietary education program
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Rochester
Cancer
Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant
RATIONALE: Antithymocyte globulin, clofarabine, and rituximab may stop the patient's immune system from rejecting the donor's stem cells when they do not exactly match the patient's blood.
- Trial name
- NCT00617929
- Testing
- anti-thymocyte globulin, rituximab, clofarabine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Hyperphosphatemia, Chronic Kidney Disease
Drug-Drug Interaction Study to Evaluate the Effect of Colestilan on the Pharmacokinetics of Single Doses of Candesartan Cilexetil in Healthy Subjects
The primary objective is to assess the effects of colestilan on the pharmacokinetic profile of candesartan cilexetil when administered at the same time as, 1 hour before, and 3 hours after the first daily dose of colestilan…
- Trial name
- NCT01976572
- Testing
- colestilan, candesartan
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma Corporation
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