Clinical trials: Chronic Nephropathy
Chronic Kidney Diseases
Parathyroid Hyperplasia in Patients With Chronic Kidney Disease.
Secondary hyperparathyroidism is an important complication in patient with chronic kidney disease . It is associated with bone complication and an increase in cardiovascular mortality The parathyroid hormone rises in these…
- Trial name
- NCT03182517
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Smoking Cessation
Tobacco Exposure and Influencing Factors of Smoking Cessation Among Chronic Kidney Disease Patients
The purpose of this study is to describe the tobacco exposure and characteristics of patients with Chronic Kidney Disease (CKD) who quit smoking, to identify patients' tobacco-related knowledge, attitude, and practice (KAP) and…
- Trial name
- NCT06303089
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 567 people
- Sponsor
- Sun Yat-sen University
End-Stage Renal Disease
Fosrenol for Enhancing Dietary Protein Intake in Hypoalbuminemic Dialysis Patients (FrEDI) Study
Protein-energy wasting, as reflected by a serum albumin <4.0 g/dL, is very common in maintenance hemodialysis (MHD) patients and associated with poor clinical outcomes including high death rates.
- Trial name
- FrEDI (NCT01116947)
- Testing
- Meals during hemodialysis accompanied by lanthanum carbonate to control phosphorus
- Volunteers
- 108 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Chronic Kidney Diseases, Hypertension
Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidney Disease
In this project the investigators will create computer reminders through user-centered design and will validate the logic using retrospective electronic health record (EHR) data.
- Trial name
- NCT03679247
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 2,026 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Chronic Kidney Disease
Intradialytic Progressive Resistance Training for Maintenance Haemodialysis Patients
The purpose of this study is to investigate the effects of a 12 week progressive resistance training during haemodialysis on muscle quantity and physical functioning in chronic kidney disease patients receiving maintenance…
- Trial name
- PRT (NCT01007838)
- Testing
- Progressive resistance training programme, Progressive resistance training
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Bangor University
End-stage Renal Disease
Pharmacokinetics and Dialyzability of Dapagliflozin in Dialysis Patients
Sodium-glucose co-transporter 2 inhibitors (Sglt2i) attenuate the incidence of cardiovascular events in individuals with preserved or mildly reduced kidney function.
- Trial name
- DARE-ESKD 1 (NCT05343078)
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- University of Campinas, Brazil
Chronic Renal Failure of Unknown Cause
CKDu Treated With Intra-arterial Infusion of Autologous SVF Cells
This is an interventional study to treat 18 patients with chronic kidney disease of unknown cause (CKDu), formerly known as Mesoamerican nephropathy (MeN), with autologous adipose tissue-derived stromal vascular fraction (SVF)…
- Trial name
- NCT05154591
- Testing
- Adipose-derived stromal vascular fraction cells
- Where
- Nicaragua
- Volunteers
- 18 people
- Sponsor
- Samuel Vilchez, PhD
Stage 5 Chronic Kidney Disease, Hemodialysis
Comparison of Outcomes Between Hemodialysis and Peritoneal Dialysis Patients in a Multi-Ethnic Asian Population
End-stage renal disease (ESRD) presents a heavy burden on a patient's psychological and social life, as well as overall quality of life (QoL).
- Conditions
- Stage 5 Chronic Kidney Disease, Hemodialysis, Peritoneal Dialysis
- Trial name
- NCT01587443
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University of Singapore
Chronic Kidney Disease
Effects of Low Protein Diet Supplemented Keto-/Amino Acid in Preventing the Progression of Chronic Kidney Disease (CKD)- ELPD Study
The purpose of this study is to determine whether low protein diet and very low protein diet supplemented keto-/amino acid is effective in preventing the progression of chronic kidney disease (CKD , stage 3b and 4).
- Trial name
- ELPD-CKD (NCT01418508)
- Testing
- low protein diet plus α-keto acid, very low protein diet plus α-keto acid
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Chronic Kidney Disease Requiring Hemodialysis, Sarcopenia
Benefits of a Renal Rehabilitation Program Adapted to Uremic Patients on Daily Hemodialysis at Low Dialysate Flow Rate.
The concept of renal rehabilitation has become increasingly important with the increasing age of patients with severe or even terminal chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Disease Requiring Hemodialysis, Sarcopenia, Rehabilitation Program
- Trial name
- NCT07413315
- Testing
- Low flow rate hemodialysis, Multidisciplinary rehabilitation program
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Brugmann University Hospital
End Stage Kidney Disease, Kidney Transplantion
The Response of the Immune System of Patients With End Stage Kidney Disease on Dialysis and Kidney Transplant Recipients Vaccinated for COVID-19
Observational study of patients with End Stage Kidney Disease on dialysis and Kidney Transplant Recipients, before and after vaccination for SARS-COV 2, after written consent, with the aim of laboratory efficacy of the vaccine…
- Conditions
- End Stage Kidney Disease, Kidney Transplantion, Covid19, Vaccination
- Trial name
- NCT04932876
- Testing
- SARS - COV 2 VACCINE
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Ioannina
Peritoneal Dialysis, Hemodialysis, Home
Experiences and Health-related Quality of Life of Informal Caregivers of Dialysis Patients
The goal of this prospective, observational, multicentre cohort study is to assess the trajectory of the experiences (both positive and negative) and health-related quality of life (HRQOL) of informal caregivers of patients who…
- Conditions
- Peritoneal Dialysis, Hemodialysis, Home, Hemodialysis, Quality of Life
- Trial name
- NCT05646615
- Where
- 33 sites in Belgium, Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- B.C. van Jaarsveld
Kidney Failure, Chronic
Effects of Probiotics on the Patients With End Stage Renal Disease (ESRD)
The purpose of this study is to investigate the effects of oral administration of probiotics on the metabolism of uremic toxins, in the patients with End Stage Renal Disease (ESRD).
- Trial name
- NCT03010735
- Testing
- probiotics
- Where
- 3 sites in China
- Volunteers
- 150 people
- Sponsor
- China Agricultural University
Kidney Disease, Chronic, Kidney Failure Chronic
Physical Exercise and Biomolecular Analysis to Reduce Uremic Toxins in Chronic Kidney Disease: An Exploratory Study
The accumulation of uremic toxins is detrimental to physiological systems and induces premature biological aging. Renal function assessment methods, such as predictive formulas, may be influenced by ancestry in Brazilians, given…
- Trial name
- DRC_LExS (NCT06910475)
- Testing
- Resistance training, Endurance training, Concurrent training
- Where
- Brazil
- Volunteers
- 1,600 people
- Sponsor
- Catholic University of Brasília
End Stage Renal Disease (ESRD)
Delivery of Soluble Ferric Pyrophosphate (SFP) Via the Dialysate to Maintain Iron Balance in Hemodialysis Patients
In maintenance hemodialysis patients, regular administration of parenteral iron by addition of soluble ferric pyrophosphate (SFP) to the dialysate, when compared to conventional dialysate, is effective in preventing the…
- Trial name
- NCT00604565
- Testing
- soluble ferric pyrophosphate (SFP)
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Charles Drew University of Medicine and Science
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
End Stage Kidney Disease
Sarcopenia and Physical Performance in Hemodialysis Patients
Many systems such as the cardiovascular, pulmonary, musculoskeletal, hematological, immunological, gastrointestinal, central nervous system are affected due to decreased kidney function.
- Trial name
- NCT04669184
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Chronic Kidney Disease
Dialysis Clinical Outcomes Revisited (DCOR) Trial
This is a randomized, open-label, parallel-design study to be conducted at 75 centers within the United States. The study will be described to hemodialysis patients.
- Trial name
- NCT00324571
- Testing
- Sevelamer hydrochloride, Calcium-based phosphate binder
- Where
- 73 sites in United States, Puerto Rico
- Volunteers
- 2,000 people
- Sponsor
- Genzyme, a Sanofi Company
Chronic Kidney Disease Stage 3 and 4, Peripheral Artery Disease (PAD)
Exercise Activity to Improve Mobility in Patients With CKD and PAD
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study.
- Trial name
- EXACT-CKDPAD (NCT06621264)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Control (Standard treatment)
- Where
- 3 sites in Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Von-Hippel Lindau, Kidney Disease, Chronic
Contrast-enhanced Ultrasound as a Screening Tool for Kidney Cancer in Patients With Von-Hippel Lindau
The purpose of this study is to determine if contrast-enhanced ultrasound can detect abnormal features of kidney lesions in patients with Von-Hippel Lindau with the same accuracy as conventional ultrasound and contrast-enhanced…
- Trial name
- CEUS-VHL (NCT03907657)
- Testing
- Perflutren lipid microsphere, Sulfur hexafluoride lipid microspheres
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
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