Clinical trials: Chronic Nephropathy
ESRD
Correlation Between Glycated Hemoglobin and Mean Plasma Glucose in Hemodialysis Patients
The investigators are studying the correlation between Hba1c and the mean plasma glucose in diabetic hemodialysis patients.We are reviewing if HbA1c is a good clinical tool to assess glycemic control over a 3 months duration in…
- Trial name
- NCT01634035
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Northwell Health
Kidney Disease
Prevention of Secondary Hyperparathyroidism With Vitamin D in Stage II/III Chronic Kidney Disease
This study will evaluate whether earlier intervention with vitamin D in stage II/III chronic kidney disease will prevent or delay secondary hyperparathyroidism.
- Trial name
- POSH-D (NCT00781417)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Atlanta VA Medical Center
Chronic Renal Failure, Hypertension
Low Sodium Dialysate and Ambulatory Blood Pressure Measurement Parameters
End stage renal disease (ESRD) is related with increased cardiovascular mortality and morbidity. Hypertension (HT) is an important risk factor for cardiovascular disorder among hemodialysis (HD) patients.
- Trial name
- NCT02621450
- Testing
- standart dialysis, low sodium dialysis
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Chronic Kidney Failure, End-Stage Renal Disease
Effect of Isometric Hand Grip Exercises Using a Dynamometer on AV Fistula Maturation and Patency in Hemodialysis Patients
Patients with chronic kidney failure who require hemodialysis depend on a surgically created connection between an artery and a vein in the arm, known as an arteriovenous fistula.
- Conditions
- Chronic Kidney Failure, End-Stage Renal Disease, Arteriovenous Fistula
- Trial name
- NCT07238855
- Testing
- Isometric Hand-Grip Exercise Training Using a Hand Dynamometer
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Contrast Induced Nephropathy
Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography
As the effect of statin use before the angiography to prevent contrast induced nephropathy (CIN) is not well-known, the aim of the current study is to assess the effect of atorvastatin on prevention of CIN in patients undergoing…
- Trial name
- CIN (NCT02113540)
- Testing
- Atorvastatin
- Where
- Iran
- Sponsor
- Isfahan University of Medical Sciences
Diabetic Kidney Disease, Chronic Kidney Diseases
Prospective Decision Impact Clinical Utility Trial of KidneyIntelX
The clinical utility trial is designed to evaluate how the results of KidneyIntelX test / platform impacts on the clinical management of type 2 diabetes patients identified as increased risk for rapid kidney function decline…
- Conditions
- Diabetic Kidney Disease, Chronic Kidney Diseases, Chronic Kidney Disease Stage 1, Chronic Kidney Disease Stage 2
- Trial name
- NCT05198284
- Testing
- KidneyIntelX
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Renalytix AI, Inc.
Hypertension;Nephropathy
Whole Exome Sequencing in CKD Hypertension
The prevalence of hypertension in patients with CKD in China is high but the control rate is low. Compared with the single blood pressure measurement method of the blood pressure of the office, ambulatory blood pressure…
- Trial name
- WESCH (NCT03718585)
- Testing
- whole exome sequencing analysis
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Anemia
Comparative Study of the Efficacy and Safety of BCD-131 and Mircera in Treatment of Anemia in CKD Patients on Dialysis
BCD-131 is pegylated darbepoetin beta. BCD-131-2 is International Multicenter Randomized Open-Label Comparative Study (Phase II) of the Efficacy and Safety of BCD-131 and Mircera in Treatment of Anemia in Chronic Kidney Disease…
- Trial name
- NCT03519243
- Testing
- BCD-131, Mircera
- Where
- 3 sites in Belarus, Russia
- Volunteers
- 75 people
- Sponsor
- Biocad
Renal Insufficiency, Chronic
Effects by Omission of Bandage Over Exit Site
Peritoneal dialysis, known as p- dialysis (PD), is a dialysis form in which the blood is purified by using the body's peritoneum. PD dependents on good access to peritoneum.
- Trial name
- EXIT (NCT02102425)
- Testing
- Patients with or without bandage over exit site
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Edith Mark
Patients With Severe Chronic Kidney Disease Being Evaluated With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson
Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging
The routine administration of 75 mg of intravenous aminophylline in patients with severe chronic kidney disease undergoing a nuclear stress test with regadenoson (Lexiscan®) can reduce or eliminate the incidence of diarrhea and…
- Trial name
- ASSUAGE-CKD (NCT01336140)
- Testing
- Aminophylline
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Rush University Medical Center
Kidney Transplant, Rejection of Renal Transplant
Development and Validation of HistoMX, a Gene-Expression Platform for Molecular Interpretation of Kidney Allograft Biopsies
This retrospective multicentre observational study developed and validated HistoMX, an automated gene-expression-based platform for multidimensional molecular interpretation of kidney allograft biopsies.
- Conditions
- Kidney Transplant, Rejection of Renal Transplant, Antibody Mediated Rejection, BK Virus Nephropathy
- Trial name
- HistoMX (NCT07700563)
- Volunteers
- 2,410 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
Chronic Kidney Disease, Anemia of Chronic Disease
Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease
The purpose of the study is to learn more about how treatment with vitamin D can affect iron metabolism and blood levels of two hormones that control iron levels, hepcidin and hemojuvelin in people with chronic kidney disease…
- Trial name
- NCT01988116
- Testing
- Oral Calcitriol 0.5 mcg once daily for 6 weeks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Kidney Failure, Chronic
Mineralocorticoid Receptor Antagonist and Kidney Allograft Histology
Chronic allograft nephropathy is one of dominant causes of long term kidney transplant failure. Its main histological determinant is interstitial fibrosis and tubular atrophy.
- Trial name
- NCT01510795
- Testing
- spironolactone
- Volunteers
- 40 people
- Sponsor
- Clinical Hospital Merkur
Antiphospholipid Antibody Syndrome, End Stage Renal Disease
Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome
Catastrophic Antiphospholipid Antibody Syndrome (CAPS) is a rare condition in which life-threatening blood clots form in multiple organs simultaneously and can lead to multi-organ system failure and death.
- Trial name
- NCT01029587
- Testing
- Eculizumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Kidney Disease, Hypercalcemia
Arterial Stiffness and Decreased Bone Buffering Capacity in Hemodialysis Patients
Renal patients have an increased risk for cardiovascular complications. There is also increased vascular calcification and bone metabolism is similarly abnormal in patients with chronic kidney disease.
- Trial name
- NCT00485706
- Testing
- high calcium dialysate
- Where
- Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Kidney Disease
Food As Medicine to Reduce CKD Burden in Health Disparity Populations
Healthy eating plays an important role in kidney and heart health, and programs that use food as medicine can help improve diet and overall health, but the best ways to support healthy eating in community settings are not well…
- Trial name
- FAME-CKD (NCT07759401)
- Testing
- Culinary Medicine Nutrition and Cooking Education
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Disease
Aliskiren Combined With Losartan in Proteinuric, Non-diabetic Chronic Kidney Disease
Study objective: To investigate the potential anti-proteinuric and renoprotective efficacy of aliskiren in addition to losartan in patients at risk of developing end-stage renal disease (ESRD) Methods: This will be a randomized…
- Trial name
- NCT01150201
- Testing
- Aliskiren, Losartan
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The University of Hong Kong
Chronic Kidney Failure
Furosemide and Creatinine Tubular Stress Test in Order to Measure Proximal Tubule Residual Function
This is a two phase study. The first part will take place at the National Institute of Cardiology in Mexico, the second phase will be made in collaboration with the University of California San Diego and University of Minnesota.
- Trial name
- NCT05105009
- Testing
- Furosemide Injection, Creatinine Powder, Iohexol
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
End-Stage Kidney Disease
Effect of Dialysis-specific Therapeutic Diet on Biochemical Parameters in Dialysis Patients
In patients with kidney failure, disturbances in bone turnover, mineral metabolism, vascular calcification, uremia, inflammation, immunity, metabolomics, nutrition, and gut microbial metabolites are frequent.
- Trial name
- NCT06377293
- Testing
- Dialysis-specific therapeutic diet
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Far Eastern Memorial Hospital
End-stage Renal Disease, Cardiorenal Syndrome
Cardiorenal Syndrome in End-Stage Kidney Disease
Cardiorenal Syndrome (CRS) is prevalent among end-stage renal disease (ESRD) patients. Recently, its prevalence is rising. There are several different clinical presentations of this syndrome.
- Conditions
- End-stage Renal Disease, Cardiorenal Syndrome, Heart Disease
- Trial name
- NCT02238093
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- Hillel Yaffe Medical Center
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