Clinical trials: Chronic Neuromuscular Pain
Neuropathic Pain
To Evaluate Long-Term Safety and Efficacy of Pregabalin in the Treatment of Neuropathic Pain After Spinal Cord Injury.
To evaluate long-term safety and efficacy of pregabalin in the treatment of neuropathic pain after spinal cord injury.
- Trial name
- NCT00141375
- Testing
- Pregabalin
- Where
- 7 sites in Australia
- Volunteers
- 132 people
- Sponsor
- Pfizer
Diabetic Neuropathies, Neuropathic Pain
Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo.
- Conditions
- Diabetic Neuropathies, Neuropathic Pain, Pain, Chronic
- Trial name
- NCT03664921
- Testing
- Omnitram Oral Tablet
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Syntrix Biosystems, Inc.
Chronic Inflammation, Mobility
Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population
This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on chronic inflammation, mobility and muscle and joint pain in an otherwise healthy population…
- Conditions
- Chronic Inflammation, Mobility, Muscle Pain, Joint Pain
- Trial name
- NCT06444763
- Testing
- Maolactin, Maltodextrin
- Where
- Australia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Renal Pelvis Cancer, Restless Legs Syndrome
Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in the Adverse Events…
- Conditions
- Renal Pelvis Cancer, Restless Legs Syndrome, Epilepsy, Neuropathic Pain
- Trial name
- NCT01138124
- Testing
- Gabapentin prescriptions
- Volunteers
- 54,202 people
- Sponsor
- GlaxoSmithKline
Cerebral Palsy, Spasticity
Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy
Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, with prenatal factors accounting for 75% of cases. CP appears in early childhood and persists with age and is characterized by permanent lesions or…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Pain Syndrome
- Trial name
- EXOCEP2GER (NCT05885139)
- Testing
- Exopulse Mollii Suit
- Where
- 2 sites in Germany
- Volunteers
- 34 people
- Sponsor
- Exoneural Network AB
Chronic Neuropathic Pain
Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)
This research is being done to study a possible treatment for refractory pain due to small fiber neuropathy (SFN). ST-503 is intended to deliver a modified copy of the gene which will ideally repress Nav1.7 tissue-related pain…
- Trial name
- NCT06980948
- Testing
- ST-503
- Where
- 11 sites in United States
- Volunteers
- 27 people
- Sponsor
- Sangamo Therapeutics
Primary Fibromyalgia
Efficacy and Safety of GRT9906 Tablets Compared to Placebo in Patients With Fibromyalgia
The study was performed in participants suffering from fibromyalgia and investigated efficacy after treatment with several doses of GRT9906 versus placebo.
- Trial name
- NCT03783910
- Testing
- GRT9906
- Where
- 6 sites in United States
- Volunteers
- 90 people
- Sponsor
- Grünenthal GmbH
Fibromyalgia, Chronic Pain
A Study of IMC-1 In Patients With Fibromyalgia
This is a randomized, double-blind, placebo-controlled, 16-week study designed to evaluate the hypothesis that tissue-resident herpes virus may be causally related to fibromyalgia symptoms or recurrence.
- Conditions
- Fibromyalgia, Chronic Pain, Myofascial Pain
- Trial name
- NCT01850420
- Testing
- IMC-1
- Where
- 12 sites in United States
- Volunteers
- 143 people
- Sponsor
- Innovative Med Concepts, LLC
Chronic Pain, Diabetic Neuropathies
Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves
The purpose of this trial is to evaluate if cebranopadol is safe and can decrease pain in patients when compared to placebo (a tablet that does not contain active product) and when compared to a marketed product containing…
- Conditions
- Chronic Pain, Diabetic Neuropathies, Diabetes Mellitus
- Trial name
- NCT01939366
- Testing
- Cebranopadol 100 µg, Cebranopadol 300 µg, Cebranopadol 600 µg
- Where
- 82 sites in United States, Austria and 6 more
- Volunteers
- 699 people
- Sponsor
- Tris Pharma, Inc.
Diabetic Polyneuropathy
Painful Diabetic Polyneuropathy Trial With a New Centrally Acting Analgesic
The purpose of this trial is to determine whether the new centrally active analgesic and MS Continus® are effective in the treatment of painful diabetic polyneuropathy.
- Trial name
- NCT00878293
- Testing
- GRT6005, MS Continus®
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Tris Pharma, Inc.
Low Back Pain, Neuralgia
Primary Care Identification Of Patients With Chronic Neuropathic Low Back Pain Study
A0081256 is a prospective, open-label, multi-centre European study designed to raise awareness and enhance the diagnosis of patients with chronic low back pain with a neuropathic pain component in primary care who are refractory…
- Trial name
- PINPOINT (NCT01298466)
- Testing
- Pregabalin
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Painful Diabetic Neuropathy
Comparison of 10 kHz SCS Combined With CMM to CMM Alone in the Treatment of Neuropathic Limb Pain
This post-market study is being conducted to document comparative safety, clinical effectiveness, and cost-effectiveness of the addition of HF10™ therapy to CMM compared with CMM alone in subjects with chronic, intractable…
- Trial name
- SENZA-PDN (NCT03228420)
- Testing
- Senza HF10 Therapy, CMM
- Where
- 4 sites in United States
- Volunteers
- 430 people
- Sponsor
- Nevro Corp
Chronic Pain, Intractable Pain
Study to Evaluate Automated Intensity Management in Patients Undergoing a BSC SCS Temporary Trial
The purpose of the study is to assess the feasibility of using information extracted from physiologic signals to automatically adjust stimulation in patients undergoing Spinal Cord Stimulation (SCS).
- Conditions
- Chronic Pain, Intractable Pain, Low Back Pain, Pain, Neuropathic
- Trial name
- AIM (NCT04909593)
- Testing
- Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston Scientific Corporation
Pain, Pain, Acute
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
This study will test the quality of opioid-related physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and…
- Conditions
- Pain, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04080037
- Testing
- Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Healthy, Peripheral Neuropathic Pain
Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food-effect of TRK-750
This is an exploratory, randomised, double-blind, placebo-controlled, Phase I study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food-effect of single and multiple, ascending oral doses of TRK-750 in…
- Trial name
- NCT03346330
- Testing
- TRK-750
- Where
- United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Toray Industries, Inc
Diabetic Neuropathy, Painful
A Study for the Treatment of Painful Diabetic Neuropathy
The purpose of the study is to determine if duloxetine can help patients with painful diabetic neuropathy.
- Trial name
- NCT00058968
- Testing
- Duloxetine hydrochloride
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- Eli Lilly and Company