Clinical trials: Chronic Obstr Lung Disease
COPD, Physical Activity
Effects of Adapted Snacktivity™ Intervention on Cognition and Self-Care in COPD Patients
This clinical trial aims to evaluate whether a culturally adapted Snacktivity™ program can improve cognitive function and self-care abilities in patients with Chronic Obstructive Pulmonary Disease (COPD) in Hong Kong.
- Conditions
- COPD, Physical Activity, Cognition, Self Care
- Trial name
- Snacktivity™ (NCT07702994)
- Testing
- Snacktivity™ Intervention, attention control
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Chronic Obstructive Pulmonary Disease, COPD Exacerbation
Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD
This trial will test a COPD prediction algorithm into a telehealth system from the previous Danish large-scale trial, TeleCare North (NCT01984840).
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD Exacerbation, COPD Exacerbation Acute, COPD
- Trial name
- NCT05218525
- Testing
- Algorithm
- Where
- Denmark
- Volunteers
- 138 people
- Sponsor
- Aalborg University
Chronic Obstructive Pulmonary Disease (COPD)
2-arm Parallel Group Study of Fixed Combination of CHF 5993 vs Ultibro® in COPD Patients
The aim of the present study is to evaluate the superiority of the fixed triple therapy with BDP/FF/GB at a daily dose of 400/24/50 mcg respectively with that of Ultibro® Breezhaler® (DPI), fixed combination of indacaterol 85 mcg…
- Trial name
- TRIBUTE (NCT02579850)
- Testing
- Central spirometry, COPD assessment test, Local laboratory Assessments
- Where
- Italy
- Volunteers
- 1,532 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Cancer, Chronic Renal Failure
Identification of Palliative Care Needs and Prognostic Factors of Survival in Tailoring Appropriate Interventions in Advanced Oncological, Renal and Pulmonary Diseases
This is a prospective observational study done on 3 patient populations (cancer, chronic pulmonary and renal disease). All patients will be treated and monitored according to the local clinical practice.
- Conditions
- Cancer, Chronic Renal Failure, Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis
- Trial name
- NCT06909968
- Testing
- palliative care
- Where
- 5 sites in Italy
- Volunteers
- 178 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Chronic Obstructive Pulmonary Disease
Neural Respiratory Drive of Patients With Chronic Obstructive Pulmonary Disease
To investigate the relationship among the neural respiratory drive (NRD), the sensation of the dyspnea and the effect of the bronchodilator on each stage COPD patients.
- Trial name
- NCT05786950
- Testing
- compound ipratropium bromide solution (3mg salbutamol and 500μg ipratropium, Boehringer Ingelheim Limited, Germany)
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
COPD
Aerosure and Six Minute Walk Distance in Severe COPD
To investigate whether high frequency airflow oscillation (HFAO), delivered using Aerosure, increases six minute walk distance (6MWD) and reduces exertional breathlessness in patients with severe chronic obstructive pulmonary…
- Trial name
- ACCORD (NCT02007590)
- Testing
- Aerosure 25 Hz
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Actegy Ltd.
COPD, Chronic Obstructive Pulmonary Disease
The Efficacy of the AIRVO Warm Humidifier as an Add on to Oxygen Therapy
The primary purpose of this study is to show whether at home usage of the AIRVO warm humidifier can potentially reduce the number of exacerbations in patients with significant respiratory insufficiency.
- Trial name
- NCT03081650
- Testing
- Airvo Humidifier
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lutheran Hospital, Indiana
Chronic Obstructive Pulmonary Disease
The Effect of Pursed Lip Breathing Exercise and Laughter Therapy Individuals With The COPD
Chronic Obstructive Pulmonary Disease is a chronic disease with increasing mortality, morbidity and prevalence in the world and in our country, and in which serious symptoms, especially dyspnea, develop.
- Trial name
- NCT05997550
- Testing
- Pursed Lip Breathing Exercise, Laughter Therapy, the control group.
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Yuksek Ihtisas University
Pulmonary Emphysema
Collateral Ventilation Effects on Response to AeriSeal System Treatment in Upper Lobe Predominant Emphysema
This study will evaluate the effects of baseline collateral ventilation status on outcomes following treatment with AeriSeal System in patients with advanced upper-lobe predominant heterogenous emphysema.
- Trial name
- CV+/- (NCT01520740)
- Testing
- Emphysematous Lung Sealant
- Where
- 13 sites in Germany, Israel
- Volunteers
- 100 people
- Sponsor
- Aeris Therapeutics
Chronic Obstructive Pulmonary Disease
Dose Finding Study of CHF 4226 for Treating Patients With COPD
The purpose of this study is to identify the optimal once-daily dose of CHF 4226 to be further developed for the treatment of patients with COPD.
- Trial name
- NCT00605891
- Testing
- carmoterol (CHF 4226), salmeterol
- Where
- 50 sites in United States, Czechia and 4 more
- Volunteers
- 278 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Obstructive Pulmonary Disease
Assessment Of Different Scores In Predicting Outcome In AECOPD Patients In Emergency Department
evaluate the value of different scores in predicting hospital mortality and Need for MV In patients presented to ED with AECOPD.
- Trial name
- NCT05793697
- Volunteers
- 139 people
- Sponsor
- Assiut University
COPD
Umbilical Cord Mesenchymal Stem Cells Transplantation in the Treatment of Chronic Obstructive Pulmonary Disease
This trial is to investigate the safety and potential therapeutic efficacy of allogeneic administration of umbilical cord-derived MSCs (UC-MSCs) as a supplementary intervention in combination with standard COPD medication…
- Trial name
- NCT04433104
- Testing
- Umbilical Cord Mesenchymal Stem Cells transplantation, drug therapy according to Vietnamese MOHS procedure
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Pulmonary Disease, Chronic Obstructive
Characteristics and Treatment Patterns of Patients With Chronic Obstructive Pulmonary Disease (COPD), Initiating Tio+Olo or Other Maintenance Therapies in the US and the UK: A Retrospective Claims Database Study
The primary objectives of the study are to use US and UK data to describe the characteristics of Chronic Obstructive Pulmonary Disease (COPD) patients according to various demographic, lifestyle, clinical, and medication use.
- Trial name
- NCT04926233
- Testing
- Tiotropium bromide + Olodaterol, Sp(t)iolto® Respimat®
- Where
- United States
- Volunteers
- 1,371,146 people
- Sponsor
- Boehringer Ingelheim
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Chronic Obstructive Pulmonary Disease
Characterization of Aerosol Generation and Transport in the Human Lung of Subjects With Chronic Obstructive Pulmonary Disease (COPD)
This study is aiming at evaluating the characteristics of particle emission in subjects with different stages of chronic obstructive pulmonary disease (COPD) compared with healthy smokers.
- Trial name
- NCT01088633
- Testing
- Exhaled particle analysis
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Chronic Obstructive Pulmonary Disease, Hypercapnia
Physiological and Clinical Changes in NHF Therapy
The study explores the changes in pressure, volume and in hypercapnia in patients with COPD and ILD. The investigators will use different application forms.
- Conditions
- Chronic Obstructive Pulmonary Disease, Hypercapnia, Interstitital Lung Disease
- Trial name
- ATMOFLOW (NCT02504814)
- Testing
- Nasal Highflow (NHF)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University of Leipzig
Effects of Obesity on COPD Mechanically Ventilated Patients
The Effect of Obesity in COPD Mechanically Ventilated Patients
Study the relationship between the body mass index and duration of mechanical ventilation \& complications in mechanically ventilated COPD patients.
- Trial name
- NCT06048549
- Volunteers
- 200 people
- Sponsor
- Assiut University
Asthma, Chronic Obstructive Pulmonary Disease
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers, Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366
CHF6366 is a novel bifunctional compound displaying both muscarinic receptor antagonist and β2-adrenergic receptor agonist properties (MABA), with the potential to deliver optimal bronchodilation after inhalation dosing via two…
- Trial name
- NCT03378648
- Testing
- CHF6366, umeclidinium bromide and vilanterol trifenatate
- Where
- United Kingdom
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
COPD
Has Pulmonary Rehabilitation a Positive Impact on Sleep Quality in Patients Suffering From COPD ?
The purpose of our study is to assess the impact of pulmonary rehabilitation on objective sleep quality in COPD patients.
- Trial name
- NCT03314558
- Testing
- pulmonary rehabilitation
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Chronic Obstructive Pulmonary Disease
Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD)
Cardiovascular health is a critical problem in patients with chronic obstructive pulmonary disease (COPD). Existing literature suggests oxidative stress from the mitochondria c driving some of the poor health outcomes in COPD.
- Trial name
- NCT05605548
- Testing
- MitoQ
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.