Clinical trials: Chronic Obstr Lung Disease
Conditions, Infections
Analysis of the Virtual Acute Care at Home Experience
The purpose of this study is to examine the implementation, intervention effectiveness, and dissemination of a digital acute care delivery model for improving selected health outcomes in the Hospital at Home population.
- Conditions
- Conditions, Infections, Heart Failure, Renal and Urinary Disorders
- Trial name
- HaH (NCT05952999)
- Testing
- Digital Care Solution as supportive personalized care, Traditional Hospital Level Care
- Where
- United States
- Volunteers
- 9,654 people
- Sponsor
- OSF Healthcare System
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Fat Metabolism in OSA and COPD
Obstructive sleep apnea (OSA) is the most common type of sleep apnea and is caused by an obstruction of the upper airways. The obstruction results in periods of intermittent hypoxia and re-oxygenation, which lead to increased…
- Conditions
- Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Obesity
- Trial name
- NCT02157844
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
COPD (Chronic Obstructive Pulmonary Disease), Caregiver
Validation of the French Version of the QASCI in Caregivers of Patients With COPD
This study aims to validate the French version of the QASCI questionnaire, initially written and validated in Portuguese language by Hipolito et al., to assess caregiving burden in chronic obstructive pulmonary disease (COPD).
- Trial name
- VALQASCI (NCT06652204)
- Testing
- questionnaire
- Where
- 2 sites in France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Chronic Obstructive Pulmonary Disease
Effect of Extremity Exercise in COPD
Objective: is to find out the effect of unsupported upper extremity exercise versus lower extremity exercise on dyspnea and lung function Methodology: Sample and design: 60 patients with Randomized study design will be included…
- Trial name
- NCT04076085
- Testing
- exercise
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Khalid University
COPD, EBV
Epstein-Barr Virus Suppression in Chronic Obstructive Pulmonary Disease (EViSCO): a Phase 2 Randomised Control Trial
COPD is a major public health problem and will shortly become the third most common cause of global mortality. There are currently no treatments that can meaningfully alter the progression of COPD or the time to death.
- Trial name
- EViSCO (NCT03699904)
- Testing
- Valaciclovir
- Where
- United Kingdom
- Volunteers
- 85 people
- Sponsor
- Belfast Health and Social Care Trust
Chronic Obstructive Pulmonary Disease, Adherence, Treatment
Role of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPD
This is an observational study examining inhaler adherence and subsequent changes in blood eosinophil count in exacerbations of Chronic obstructive pulmonary disease (COPD) population.
- Trial name
- INCLINE (NCT05814484)
- Where
- United Kingdom
- Volunteers
- 104 people
- Sponsor
- University of Leicester
Emphysema
Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function
EMPROVE is a multicenter, prospective, randomized, controlled study designed to evaluate the safety and long-term effectiveness of the Spiration Valve System in patients with emphysema.
- Trial name
- EMPROVE (NCT01812447)
- Testing
- Spiration Valve System, Medical Management
- Where
- 34 sites in United States, Canada
- Volunteers
- 172 people
- Sponsor
- Olympus Corporation of the Americas
Chronic Obstructive Pulmonary Disease
Study on Single and Multiple Atomization Inhalation of HRS-9821 Suspension for Inhalation in Healthy Subjects and COPD Patients
The increased safety and tolerance of single and multiple atomized inhalation of HRS-9821 suspension for inhalation doses in healthy subjects and COPD patients.
- Trial name
- NCT05622864
- Testing
- HRS-9821
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Severe Chronic Obstructive Pulmonary Disease
Breathing Control Exercises in Patients With Chronic Obstructive Pulmonary Disease.
The purpose of this study is to test whether breathing control exercises embedded in occupational therapy sessions have an impact on quality of life and dyspnea in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT05199987
- Testing
- Standard Occupational Therapy, Occupational Therapy with Breathing Control Exercises
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pulmonary Disease, Chronic Obstructive
Study Evaluating the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to evaluate the 24-hour spirometry effect (FEV1) of FF/VI 100/25mcg once daily compared with Fluticasone Propionate/Salmeterol 250/50mcg twice daily over a 12-week treatment period in subjects with…
- Trial name
- NCT01323621
- Testing
- Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg, Fluticasone Propionate 250mcg / salmeterol 50mcg, Salbutamol as needed
- Where
- 51 sites in United States, Germany and 4 more
- Volunteers
- 512 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease With Acute Exacerbation, Unspecified
Comparison of Two Oxygen Setting During Non-invasive Mechanical Ventilation of Chronic Obstructive Pulmonary Disease
Hypoxaemic patients with exacerbations of chronic obstructive pulmonary disease (COPD) are at some risk of carbon dioxide (CO2) retention during oxygen therapy.
- Trial name
- OXYSET (NCT02563314)
- Testing
- Non-invasive mechanical ventilation - Normoxia, Non-invasive mechanical ventilation - Controlled hypoxemia
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chronic Obstructive Lung Disease (n=10), Interstitial Lung Disease (n=10)
Cardiorespiratory Response During Whole Body Vibration Training in Patients With Chronic Lung Disease
Whole body vibration training seems to be a useful adjunct in exercise training in patients with severe COPD. The basic principle relies on reflectory muscle contractions caused by a vibration stimulus.
- Trial name
- NCT01898143
- Testing
- Whole body vibration
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Chronic Obstructive Pulmonary Disease
Residential Cleaning of Indoor Air to Protect COPD Patients
This study looks at whether air cleaning devices put in the bedroom and living room of your home could reduce the irritation of your lungs and body that is caused by indoor air pollution.
- Trial name
- CARE (NCT03750292)
- Testing
- HEPAirX air filter, control air filter
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Rochester
Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis)
Construction and Validation of an Impulse Oscillometry (IOS)-Based Platform for Screening, Diagnosis, and Management of Chronic Airway Diseases
This is a multicenter, observational study aiming to construct and validate an Impulse Oscillometry (IOS)-based platform for the screening, diagnosis, and management of chronic airway diseases (COPD and asthma).
- Trial name
- NCT07910409
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
COPD (Chronic Obstructive Pulmonary Disease), COPD
Balance Training Following Pulmonary Rehabilitation on Balance in People With Chronic Obstructive Pulmonary Disease (COPD)
This study aims to see if a co-designed balance training programme called Sport4Steadiness (S4S), is acceptable to people with COPD and if the study procedures, including recruitment and the collection of outcomes, is feasible.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD, Balance Exercise, Falls, Intervention
- Trial name
- B-PuRe (NCT07750821)
- Testing
- Sport4Steadiness
- Where
- 3 sites in United Kingdom
- Volunteers
- 77 people
- Sponsor
- Samantha Harrison
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects
This is an open-label,partially randomized, four-period study in healthy male subjects to assess the bioavailability and pharmacokinetics of a single dose of AZD7594 when administered intravenously, orally and inhaled via two…
- Trial name
- NCT02648438
- Testing
- AZD7594 Solution for infusion (150 μg intravenous formulation), AZD7594 Oral suspension (1200 μg oral formulation), AZD7594 Inhalation powder (400 μg) by DPI Device 1 (monodose inhaler)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
COPD, Healthy
The Effectiveness of Dual-task Exercises in Individuals With COPD
The goal of this clinical trial is to evaluate the effect of dual-task performance on motor and cognitive functions and to determine the effect of dual-task exercises given together with the pulmonary rehabilitation program on…
- Trial name
- NCT05930158
- Testing
- Dual Task Exercises, Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pulmonary Disease, Chronic Obstructive
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI
The study is a prospective, observational study of patients admitted to the BLOCK COPD network hospitals with acute AMI and Chronic Obstructive Pulmonary Disease (COPD) to determine the prevalence of COPD in patients admitted to…
- Trial name
- BLOCK2 (NCT04717492)
- Testing
- Observational
- Where
- 24 sites in United States
- Volunteers
- 584 people
- Sponsor
- University of Minnesota
COPD
Evaluation by Electrical Impedancemetry of the Variation in Lung Volumes Under Non-invasive Ventilation (NIV) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The aim of this physiologic research is to assess lung volumes variations under NIV in stable COPD patients to understand the impact of "high-intensity" ventilation following the current recommendations.
- Trial name
- Eval 3V-BPCO (NCT05953298)
- Testing
- Electrical impedance tomography (EIT)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Comparative Effectiveness of Telemedicine in Primary Care
Leveraging a natural experiment approach, the investigators will examine rapidly changing telemedicine and in-person models of care during and after the COVID-19 crisis to determine whether certain patients could safely choose to…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, Diabetes
- Trial name
- NCT04684836
- Testing
- Exposure to telemedicine, after the onset of the pandemic
- Where
- 4 sites in United States
- Volunteers
- 33,100 people
- Sponsor
- Weill Medical College of Cornell University
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