Clinical trials: Chronic Obstr Lung Disease
Chronic Obstructive Pulmonary Disease
Safety and Tolerability QAT370 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease
This study will assess the safety and tolerability of QAT370 compared to tiotropium in patients with COPD.
- Trial name
- NCT00532350
- Testing
- QAT370, Tiotropium
- Where
- 3 sites in Germany
- Volunteers
- 22 people
- Sponsor
- Novartis
Pulmonary Arterial Hypertension, Chronic Obstructive Pulmonary Disease
Impact of Inhaled Treprostinil Sodium on Ventilation Perfusion Matching
The purpose of this study is to see how inhaled treprostinil sodium (Tyvaso) affects the amount of air and blood that reach the alveoli, or tiy air sacs, in the lungs of patients with Group 1 Pulmonary Arterial Hypertension with…
- Trial name
- NCT01494896
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Chronic Obstructive Pulmonary Disease
Is COPD a Risk Factor for Cardiovascular Disease?
Patients with chronic obstructive pulmonary disease suffer from significant cardiovascular morbidity and mortality. This study wants to determine whether chronic obstructive pulmonary disease might be a risk factor for coronary…
- Trial name
- NCT02162095
- Where
- Switzerland
- Volunteers
- 162 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease
Evaluation in Individuals with COPD and Asymptomatic Individuals
The literature does not provide sufficient information on the evaluation of frailty, handgrip strength, physical activity, kinesiophobia, and fatigue in elderly individuals with Chronic Obstructive Pulmonary Disease and…
- Trial name
- NCT06077357
- Testing
- MMSE Test, PASE Test, The PRISMA-7 Frailty Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Chronic Obstructive Pulmonary Disease
A Scintigraphy Study of PT010 in COPD Patients
This study is a single treatment period, single dose gamma scintigraphy study investigating the deposition in the lungs of a Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dose Inhaler (BGF-MDI).
- Trial name
- RD708/34000 (NCT03906045)
- Testing
- BGF-MDI
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- AstraZeneca
Asthma, Chronic Obstructive Pulmonary Disease
Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether macrolide therapy is effective in treating patients hospitalized with asthma exacerbations or chronic obstructive pulmonary disease (COPD)exacerbations.
- Trial name
- NCT00181272
- Testing
- azithromycin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease
Effects of Diaphragm and Abdominal Muscle Training on PFT and Dyspnea Among COPD Obstructive Pulmonary Disease Patients.
It will be a randomized control trial at Services Hospital Lahore through convenience sampling technique which will be allocated through simple random sampling through sealed opaque enveloped in to Group A and Group B .
- Trial name
- NCT05587829
- Testing
- • Diaphragmatic breathing technique, basic breathing technique
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
COPD, Muscle Tone Abnormalities
Viscoelastic Properties of Respiratory and Peripheral Muscles of COPD Patients
The aim of this study was to compare the viscoelastic properties of auxiliary respiratory muscles and peripheral muscles of chronic obstructive pulmonary disease patients with healthy subjects.
- Trial name
- NCT06580353
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Chronic Obstructive Pulmonary Disease (COPD)
Low Fat-free Mass in Prognosis of People With Chronic Obstructive Pulmonary Disease
The effects of low fat-free mass in Prognosis of people with chronic obstructive pulmonary disease (COPD) as regard clinical evaluation using BODE index, GOLD ABE assessment ( Gold 2024 ) functional evaluation using spirometry…
- Trial name
- NCT07541053
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Chronic Obstructive Pulmonary Disease
AMPLIFY - D6571C00001 Duaklir USA Phase III Study
This is a multiple dose, randomized, parallel, double-blind, double-dummy, multicenter and multinational Phase III study to determine the efficacy and safety of Aclidinium bromide 400μg/Formoterol Fumarate (AB/FF) 12 μg compared…
- Trial name
- NCT02796677
- Testing
- Aclidinium bromide 400 μg/Formoterol Fumarate 12 μg (AB/FF 400/12 μg), Aclidinium bromide 400 μg (AB 400 μg), Formoterol fumarate 12 μg (FF 12 μg)
- Where
- 163 sites in United States, Bulgaria and 8 more
- Volunteers
- 1,595 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Moderate
Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD
Recruitment of patients with COPD. Assessment of clinical status, determination of vitamin D and cathelicidin levels. In the group with vitamin D deficiency, patients receive cholecalciferol (vitamin D) daily for 3 months.
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe
- Trial name
- COPD (NCT05431218)
- Testing
- Cholecalciferol Liquid
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Karaganda Medical University
Chronic Obstructive Lung Disease
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to determine whether genetic factors contribute to an individuals risk of developing obstructive lung disease from smoking cigarettes.
- Trial name
- NCT00018408
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cancer, Congestive Heart Failure (CHF)
Outlook Quality of Life Intervention Study
The purpose of this study is to determine whether discussions of life story, forgiveness, and future goals improve quality of life for patients with serious illness.
- Conditions
- Cancer, Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD), End Stage Renal Disease (ESRD)
- Trial name
- NCT01044290
- Testing
- Life Completion, Attention Control
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- VA Office of Research and Development
COPD Postural Control IMT
The Effect of Inspiratory Muscle Training on Postural Control in Chronic Obstructive Pulmonary Disease
Deficits in postural control are increasingly recognized among the important secondary impairments in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT03790410
- Testing
- Complex pulmonary rehabilitation, Inspiratory muscle training
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- Szeged University
Chronic Obstructive Pulmonary Disease (COPD), Inflammatory Disease
Endothelial Dysfunction in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
The purpose of the study is to determine a possible association between the clinical entity of exacerbation, markers of systemic inflammation and endothelial dysfunction in patients with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Inflammatory Disease, Endothelial Dysfunction
- Trial name
- EDAECOPD (NCT01460082)
- Where
- Austria
- Volunteers
- 29 people
- Sponsor
- LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology
Chronic Obstructive Pulmonary Disease
Rehabilitation of Patients With Lung Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is characterized by the obstruction is not fully reversible airway, where the severity of the disease and the prognosis is not determined solely by changes in lung function.
- Trial name
- PR (NCT02468635)
- Testing
- upper limb exercises, without training for upper limb
- Where
- Brazil
- Volunteers
- 2 people
- Sponsor
- Federal University of Bahia
COPD
Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital
The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with hypoxemia/respiratory distress.
- Trial name
- NCT07222410
- Testing
- Closed loop oxygen control, Manual titration
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Fisher and Paykel Healthcare
Pulmonary Disease, Chronic Obstructive
Postmarketing Surveillance Study to Assess Handling and Patient Satisfaction on Berodual® Respimat® Solution for Inhalation in Patients With Chronic Obstructive Pulmonary Disease
New perceptions about handling and patient satisfaction of the everyday use of Berodual® Respimat® in patients with chronic obstructive lung disease (COLD).
- Trial name
- NCT02231320
- Testing
- Berodual® Respimat® - inhaler
- Volunteers
- 236 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)
This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing strength training prior to initiating exercise…
- Trial name
- NCT01058213
- Testing
- Resistance training, Aerobic training
- Where
- United States
- Volunteers
- 354 people
- Sponsor
- University of Illinois Chicago
Cancer, Chronic Heart Failure
Open Video System in Medicine (oVID)
Currently, there are no telemedical visits between patients and/or their relatives and a palliative physician for the evaluation of symptom and progress monitoring.
- Conditions
- Cancer, Chronic Heart Failure, Chronic Obstructive Pulmonary Disease, Palliative Care
- Trial name
- oVID (NCT06054048)
- Testing
- Telemedicine
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- University Hospital Muenster