Clinical trials: Chronic Obstruct Airways Disease
Pulmonary Disease, Chronic Obstructive
Analyzing Lung Tissue in People With and Without Chronic Obstructive Pulmonary Disease Who Are Undergoing Lung Transplantation
Chronic obstructive pulmonary disease (COPD) is a long-term lung disease. People with COPD have difficulty breathing because of lung damage.
- Trial name
- NCT00756522
- Testing
- There is no intervention. Study is observational.
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Washington University School of Medicine
Chronic Obstructive Pulmonary Disease
Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo
Chronic Obstructive Pulmonary Disease is a leading cause of global morbidity and mortality, especially in low- and middle-income countries. Exacerbations accelerate disease progression and increase the risk of death.
- Trial name
- iCHOROS (NCT07069829)
- Where
- 36 sites in Argentina, Colombia and 10 more
- Volunteers
- 1,400 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Study to Evaluate Efficacy and Safety of Bronpass Tab. in Patients With Chronic Obstructive Pulmonary Disease
This clinical trial is a multicenter, randomized, double-blind, placebo-controlled, parallel-group dose-response phase 2 clinical trial study to evaluate the efficacy and safety of Bronpass Tab.
- Trial name
- NCT06434792
- Testing
- Bronpass Tab.
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Chronic Obstructive Pulmonary Disease (COPD)
Monitoring Coughs for the Early Detection of Worsening COPD
This study is for adults with COPD. Flare-ups of COPD, also known as exacerbations, can be serious and lead to hospital stays. The purpose of this research is to see if continuously and automatically monitoring a person's coughs…
- Trial name
- Hyfe-EPOC (NCT07212439)
- Where
- 3 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pulmonary Rehabilitation, Chronic Obstructive Lung Disease
Does Neuromuscular Electrical Stimulation Benefit the Functional Ability of Elderly Patients With Chronic Obstructive Lung Disease
Background: Patients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES) may provide an alternative method of…
- Conditions
- Pulmonary Rehabilitation, Chronic Obstructive Lung Disease, Neuromuscular Electrical Stimulation, Pulmonary Function (FEV1/FVC)
- Trial name
- NEMS for COPD (NCT05838911)
- Testing
- Study Group chest physiotherapy program combined with neuromuscular electrical stimulation (NMES), Control Group Chest physical therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
COPD
Efficacy and Safety of 400 μg Twice Daily of Aclidinium Bromide vs. Placebo When Administered to Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study was to observe the Efficacy and safety of 400 μg twice daily of aclidinium bromide vs. placebo when administered to patients with moderate to severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01636401
- Testing
- aclidinium bromide 400 μg
- Where
- South Korea
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
COPD
Impact of COPD on Muscle Regeneration
Muscle weakness and atrophy are important consequences of chronic obstructive pulmonary disease (COPD) and can affect both respiratory and peripheral muscles.
- Trial name
- NCT02557165
- Testing
- Muscle biopsies
- Volunteers
- 27 people
- Sponsor
- Laval University
Insomnia
Cognitive Behavioral Therapy for Insomnia in People With Chronic Obstructive Pulmonary Disease(COPD)
A two-phase research study is being conducted. In Phase 1 of the study, the cognitive behavioral therapy intervention for insomnia was implemented in a small (n = 5) group of people with moderate to severe COPD and insomnia.
- Trial name
- NCT01072292
- Testing
- CBT-I
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Illinois Chicago
Chronic Obstructive Pulmonary Disease (COPD)
Long Term Safety and Tolerability of QVA149 Versus Tiotropium in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD)
This is a 52-week treatment, multi-center, randomized, open label, parallel group study to assess the long term safety and tolerability of once-daily QVA149 (indacaterol and NVA237 ([glycopyrronium bromide]) using tiotropium as…
- Trial name
- NCT01285492
- Testing
- QVA149, Tiotropium
- Where
- 35 sites in Japan
- Volunteers
- 160 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Medicated Aerosol Delivery Using A Jet Nebulizer Versus A Vibrating Mesh Nebulizer in COPD Exacerbation
Delivery of inhaled short-acting bronchodilators (SABD) is standard of care in the emergency department (ED) for exacerbation of COPD, the goal of such being rapid reversal of airflow obstruction.
- Trial name
- NCT03051971
- Testing
- Vibrating Mesh Nebulizer, Jet Nebulizer
- Where
- United States
- Sponsor
- Medstar Health Research Institute
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD
Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease
This investigator-initiated, prospective, single center, randomized, controlled clinical trial enrolled patients with stable Global Initiative for Chronic Obstructive Lung Disease stage II-IV chronic obstruction pulmonary…
- Trial name
- NCT04843696
- Testing
- cuirass ventilator (cuirass diameter 21 cm or 34 cm, Dima Italia Srl.,Bologna, Italy), breathing training, and an educational program (relaxation techniques and a home pacing walking exercise)
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Obstructive Pulmonary Disease
Multiple Dose Healthy Volunteer Safety Pharmacokinetics Study
Multiple dose safety and pharmacokinetics in healthy male subjects
- Trial name
- NCT00864786
- Testing
- PF03635659
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
(In)Voluntary Assessed Quadriceps Muscle Endurance in COPD
The primary objective is to assess the relation between involuntary and voluntary assessed quadriceps muscle endurance in patients with COPD. We hypothesized a good correlation (>0.8) between the measurements.
- Trial name
- Bionic (NCT05427773)
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Radboud University Medical Center
Chronic Obstructive Pulmonary Disease Moderate
The Effects of RPL554 in Addition to Tiotropium in COPD Patients
This is a phase II, randomised, double blind, placebo controlled, complete block, three way crossover study to investigate treatment with nebulised RPL554 and tiotropium together in patients with moderate to severe chronic…
- Trial name
- NCT03028142
- Testing
- 1.5 mg RPL554 plus tiotropium, 6 mg RPL554 plus tiotropium
- Volunteers
- 30 people
- Sponsor
- Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
Chronic Obstructive Pulmonary Disease, Neuromuscular Disease
Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation
The critical nature of respiratory diseases, the continuously increasing prevalence of these conditions, and the subjective perception of patients vis-à-vis their pulmonary function and health status underscore the importance of…
- Conditions
- Chronic Obstructive Pulmonary Disease, Neuromuscular Disease, Chest Wall Disorders, Obesity Hypoventilation Syndrome
- Trial name
- TeleMotiNIV (NCT01560741)
- Testing
- Telemonitoring tools, Usual Care
- Where
- Portugal
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Joao
Chronic Obstructive Pulmonary Disease (COPD), Asthma
A Study to Evaluate the Disposition of Drug in Body and Safety After Administration of Single Inhaled Doses of Drugs Abediterol and AZD7594 Administered Alone, in Fixed Dose Combination and in Free Combination Using the Dry Powder Inhaler in Healthy Male Participants
AZD7594 is a non steroidal, potent and selective modulator of the glucocorticoid receptor (GR) under development for once daily inhaled treatment of chronic obstructive pulmonary disease (COPD) and asthma.
- Trial name
- NCT02967159
- Testing
- Abediterol, AZD7594, AZD7594/abediterol
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Microcirculatory Status, Spectroscopic Analysis
Near-Infrared Spectroscopy Measurements in Chronic Obstructive Pulmonary Disease
Participants were selected based on three groups: healthy, chronic obstructive pulmonary disease, and chronic renal disease. NIRS was used to measure tissue oxygenation on the thenar region of the right hand.
- Conditions
- Microcirculatory Status, Spectroscopic Analysis, COPD, Renal Failure
- Trial name
- NIRS (NCT06976762)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Chronic Obstructive Pulmonary Disease
Chest Wall Muscle Stretching and Acute Effects in Chronic Obstructive Pulmonary Disease
The study hypothesis is chest wall muscle stretching increase distribution of volume variation of thoracoabdominal wall and reduce electromyographic activity of respiratory muscles in patients with Chronic Obstructive Pulmonary…
- Trial name
- NCT01826669
- Testing
- Stretching
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Universidade Federal de Pernambuco
Chronic Obstructive Pulmonary Disease
Evaluation of the Effectiveness, Safety, and Cost of a Smart Hospital System for Patients With Chronic Obstructive Pulmonary Disease
This study aims to analyze the effectiveness/safety/cost of the Smart Homespital system that provides a service that allows patients with Chronic Obstructive Pulmonary Disease to easily access and use biosignals generated using…
- Trial name
- NCT06601777
- Testing
- Immediate application of the Smart Homespital system, Delayed application of the Smart Homespital system after 3 months
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Yonsei University
Chronic Obstructive Pulmonary Disease Exacerbation
Volatolom Variation in Severe COPD During Hospitalization for Exacerbation and After Hospitalization (VOC-BPCO-Exa)
Chronic obstructive pulmonary disease (COPD) is a public health issue due to its prevalence of 8% in the general population (although it is underestimated), particularly due to the number of severe patients suffering from chronic…
- Trial name
- VOC-BPCO-Exa (NCT04816695)
- Testing
- VOC analysis
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hopital Foch
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.