Clinical trials: Chronic Obstructive Pulmonary
Pulmonary Disease, Chronic Obstructive
Safety of Tiotropium + Olodaterol in Chronic Obstructive Pulmonary Disease (COPD) Patients in Taiwan: a Non-interventional Study Based on the Taiwan National Health Insurance (NHI) Data
The aim of this real world study is to assess the safety profile of tiotropium/olodaterol (Tio/Olo).
- Trial name
- NCT05393245
- Testing
- Tiotropium+Olodaterol, Spiolto Respimat, Long-acting muscarinic antagonists (LAMAs)
- Where
- China
- Volunteers
- 19,467 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Nocturnal Breathing and Sleep in Patients With Chronic Obstructive Pulmonary Disease Staying at Altitude
The purpose of this study is to evaluate whether nocturnal breathing and sleep of patients with chronic obstructive pulmonary disease (COPD) are disturbed during a stay at moderate altitude.
- Trial name
- NCT01870830
- Testing
- Altitude exposure
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease, Bronchial Asthma
Evaluation of Novel Lung Function Parameters and Quantitative Computed Tomography (qCT) in Patients With Pulmonary Disease
Current diagnostic tools used in pulmonary disease often do not meet the challenges set by the respective pathophysiology. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the…
- Conditions
- Chronic Obstructive Pulmonary Disease, Bronchial Asthma, Interstitial Lung Disease
- Trial name
- NCT02826265
- Testing
- multiple breath washout test (MBW), impulse oscillometry (IOS), body plethysmography (BP)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsmedizin Mannheim
ILD, COPD
Impact of Remote Vital Signs Monitoring in People Using Long-term Oxygen Therapy
Assess quality of life of patients using prolonged oxygen therapy
- Trial name
- ILD; COPD (NCT06882265)
- Testing
- Group Monitoring, Control Group
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
COPD
Effects of Long Term Macrolide Antibiotic Therapy in Patients With COPD
The purpose of this study is to determine whether long term treatment with oral erythromycin is effective in the treatment of subjects with Chronic Obstructive Pulmonary Disease (COPD) by reducing the number of exacerbations and…
- Trial name
- NCT00147667
- Testing
- Erythromycin
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Royal Free and University College Medical School
Pulmonary Disease, Chronic Obstructive
Pilot Study Comparing Tiotropium (Spiriva) to Salmeterol (Serevent) Plus Fluticasone (Flixotide) in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to estimate the comparative bronchodilator effect size and variability for tiotropium (Spiriva, 18 µg q.d.) with the free combination of salmeterol (Serevent, 50 µg b.i.d.) and fluticasone…
- Trial name
- NCT00239499
- Testing
- Tiotropium, Salmeterol plus Fluticasone
- Where
- 12 sites in South Africa
- Volunteers
- 107 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Prednisone Administration in Quiescent COPD Patients to Determine the Effect on Gene Expression
In this study, prednisone dose, day/time administration will be controlled in a stable COPD patient population to determine its effect on peripheral whole blood gene expression.
- Trial name
- NCT02534402
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
COPD, Hypercapnic Respiratory Failure
HFNC vs NPPV After Early Extubation for Patients With COPD
High-flow nasal cannula oxygen therapy(HFNC) has proved no significant difference compared with noninvasive positive pressure ventilation (NPPV) in preventing postextubation respiratory failure and reintubation in patients with…
- Trial name
- NCT04156139
- Testing
- HFNC, NPPV
- Where
- China
- Volunteers
- 502 people
- Sponsor
- Chinese PLA General Hospital
Chronic Obstructive Pulmonary Disease, Chronic Respiratory Failure
Yiqi Huoxue Huatan Granule for Reducing Mortality in COPD With Chronic Respiratory Failure
This study aims to establish the treatment scheme of Yiqi Huoxue Huatan granule for chronic obstructive pulmonary disease (COPD) with chronic respiratory failure (CRF), reducing mortality, improving quality of life and forming…
- Trial name
- NCT04208581
- Testing
- Yiqi Huoxue Huatan granule
- Where
- China
- Volunteers
- 372 people
- Sponsor
- Peking University People's Hospital
Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disorder and Acute Exercise
For this study a resistance bout will be performed in order to promote the robust response of protein synthesis. Type II muscle fibers often exhibit more atrophy than type I fibers in COPD subjects therefore specifically…
- Trial name
- NCT02780219
- Testing
- stable amino acid infusion, acute exercise with amino acid infusion, 24-hour post exercise amino acid infusion
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pulmonary Disease, Chronic Obstructive
A Study on Whether Patients Prefer the Spiriva® Respimat® or the Spiriva® Handihaler® for Treating Their Chronic Obstructive Pulmonary Disease (COPD)
The objective of this study is to investigate the patient acceptability/preference of Respimat® compared with Handihaler® in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) to demonstrate the…
- Trial name
- NCT03964207
- Testing
- Tiotropium Respimat® (T1), Tiotropium Handihaler® (T2)
- Where
- 8 sites in China
- Volunteers
- 72 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease, COPD
A Single-dose Study to Investigate the Effects of 4 Different Doses of Inhaled AZD8683 in Chronic Obstructive Pulmonary Disease (COPD) Patients
This study in Chronic Obstructive Pulmonary Disease (COPD) patients will investigate the bronchodilatory effect of AZD8683. AZD8683 will be tested versus placebo and an active comparator.
- Trial name
- NCT01708057
- Testing
- AZD8683, Tiotropium
- Where
- 6 sites in Poland, Sweden
- Volunteers
- 3 people
- Sponsor
- AstraZeneca
COPD
Long-term Activity Coaching in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity around the world. Studies revealed that patients with COPD are less active than age-matched healthy controls and activity level decreases…
- Trial name
- NCT04139200
- Testing
- Type 1 physical activity tele coaching intervention, Type 2 physical activity tele coaching intervention
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- KU Leuven
COPD, Muscle Weakness
Feasibility of Strength Training in Patients Hospitalized Due to COPD
To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD
- Trial name
- NCT01981200
- Testing
- Resistance training in AECOPD
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Frederikssunds Hospital, Denmark
Chronic Obstructive Pulmonary Disease, Heart Failure
HFpEF and 2-year Mortality of COPD Patients
This study was designed to assess potential relationship between heart failure with preserved ejection fraction and 2- year mortality of patients with chronic obstructive pulmonary disease
- Trial name
- THERESE (NCT04277429)
- Testing
- Cardiac function assessment
- Where
- 2 sites in Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Olomouc
Pulmonary Disease, Chronic Obstructive, Bacterial Infections
Study of the Involvement of IL-17 / IL-22 Pathway in Bacterial Exacerbations of COPD
Chronic obstructive pulmonary disease (COPD) is a worldwide chronic inflammatory disease of the airways linked to environmental exposure.
- Trial name
- COPD1722 (NCT02655302)
- Testing
- Sample collecting, Lung function measure
- Where
- 4 sites in France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Lille
COPD Exacerbation Acute
Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD
The investigators hypothesized that the empirical use of fluoroquinolones together with beta-lactam antibiotics will change their therapeutic success in patients with acute exacerbations of COPD compared to that in patients in…
- Trial name
- COPD (NCT04879030)
- Testing
- Beta-Lactams, Fluoroquinolone
- Where
- Vietnam
- Volunteers
- 170 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Cancer, Heart Failure
Goal Concordant Care Learning Laboratory
The goal-concordant care lab will develop and test strategies to optimize communication in advanced serious illness.
- Conditions
- Cancer, Heart Failure, Copd, Dementia
- Trial name
- NCT05879211
- Testing
- Feedback
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Duke University
Chronic Obstructive Pulmonary Disease
Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude
In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on exercise performance at altitude in patients with COPD.
- Trial name
- NCT03177837
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 176 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease
Effects of Kinesiotaping Technique on Lung Function & Functional Capacity of Chronic Obstructive Lung Disease Patients
This study is designed to determine the effects of diaphragmatic kinesiotaping (KT) facilitation technique on pulmonary function, functional capacity and forward head posture of chronic obstructive lung diseases (COPD) patients.
- Trial name
- COPD (NCT05258175)
- Testing
- KT, Standardized physiotherapy protocol
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.