Clinical trials: Chronic Obstructive Pulmonary
Pulmonary Emphysema
Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)
The purpose of this study is to demonstrate the safety and efficacy of AeriSeal System treatment plus optimal medical therapy compared in patients with advanced upper lobe predominant (ULP) heterogeneous emphysema.
- Trial name
- ASPIRE (NCT01449292)
- Testing
- Treatment plus Optimal Medical Therapy, Optimal Medical Therapy
- Where
- 40 sites in United States, France and 5 more
- Volunteers
- 300 people
- Sponsor
- Aeris Therapeutics
COPD (With - Without Rehabilitation)
Effects of Structural Integration on Chest Wall Expansion Among COPD Patients
The present study aims to investigate the effects of the 10-Series of Structural Integration on chest wall expansion in patients with stable COPD using a randomized controlled trial design.
- Trial name
- NCT07752420
- Testing
- Structural Integration with Conventional Pulmonary Rehabilitation, Pulmonary Rehabilitation only
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Green International University
Pulmonary Disease, Chronic Obstructive
Training of Inhalation Technique in Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Patients - a Pilot Study
Inhalation drugs are essential in the treatment of COPD, in controlling symptoms and preventing exacerbations. The aim of this pilot study is to collect data necessary for the planning of future efficacy trials.
- Trial name
- NCT03691324
- Testing
- Inhalation technique training and discharge service
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University College
Asthma, COPD
Blood Collection From Individuals With Lung Disease for Genetic Studies (Qatar)
This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, COPD (chronic obstructive pulmonary disease), interstitial lung…
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- Q-BC (NCT00504361)
- Where
- Qatar
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle Wasting
A significant proportion of COPD subjects experience muscle wasting, which has been associated with increased morbidity, impaired physical functioning, and a poor quality of life.
- Trial name
- NCT01388920
- Testing
- Tesamorelin
- Volunteers
- 3 people
- Sponsor
- Theratechnologies
Chronic Obstructive Pulmonary Disease (COPD)
Targeted Retreatment of COPD Exacerbations
This study investigates the effects of targeted re-treatment of patients who do not recover from an exacerbation of COPD. Half of the patients will receive ciprofloxacin while the other half will receive a placebo.
- Trial name
- NCT02300220
- Testing
- Ciprofloxacin
- Where
- 4 sites in United Kingdom
- Volunteers
- 144 people
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease
Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients
Chronic obstructive pulmonary disease is a respiratory disease that results in progressive airflow limitation and respiratory distress.
- Trial name
- NCT04120142
- Testing
- Pulmonary rehabilitation+IMT, Pulmonary rehabilitation
- Where
- Tunisia
- Volunteers
- 34 people
- Sponsor
- Faculty of Medicine, Sousse
Pulmonary Disease, Chronic Obstructive
Respiration Rate Monitoring in COPD Patients
Assess the feasibility of using remote respiration rate monitoring as a component of home care, how respiration rate data may be used in combination with other data to potentially improve response to symptoms, and to generate…
- Trial name
- NCT03030313
- Testing
- Reassure Non-Contact Respiration Monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- ResMed
Chronic Obstructive Pulmonary Disease, COPD
Predictors of Acute Exacerbation in Patients With COPD - an Observational Study
Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by respiratory problems and poor airflow with dyspnea and cough being the main symptoms.
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, COPD Exacerbation, COPD Exacerbation Acute
- Trial name
- PACE (NCT04140097)
- Testing
- Prospective monitoring of a large variety of parameters
- Where
- Germany
- Volunteers
- 355 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Pulmonary Disease, Chronic Obstructive
Postmarketing Surveillance Study to Assess Handling and Patient Satisfaction on Berodual® Respimat® Solution for Inhalation in Patients With Chronic Obstructive Pulmonary Disease
New perceptions about handling and patient satisfaction of the everyday use of Berodual® Respimat® in patients with chronic obstructive lung disease (COLD).
- Trial name
- NCT02231320
- Testing
- Berodual® Respimat® - inhaler
- Volunteers
- 236 people
- Sponsor
- Boehringer Ingelheim
Asthma, Respiratory Tract Disease
Houston "Breathe Easy" Healthy Homes-Based Model for Multifamily Rental Communities
The primary purpose of this pragmatic randomized clinical trial is to examine whether the addition of a phone-based multicomponent environmental intervention customized for Houston public housing residents with asthma will result…
- Conditions
- Asthma, Respiratory Tract Disease, Lung Diseases, Sinusitis, Chronic
- Trial name
- NCT05345080
- Testing
- Exposure-Reduction Intervention
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Baylor College of Medicine
COPD Exacerbation, Pulmonary Rehabilitation
Virtual Reality in COPD Exacerbation
In addition to conventional pulmonary rehabilitation, virtual reality will be applied during the hospitalization period of individuals hospitalized for COPD exacerbation.
- Trial name
- NCT05687396
- Testing
- virtual reality, conventional pulmonary rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Pamukkale University
Chronic Obstructive Pulmonary Disease, Family
Partnership-based Nursing Practice for Lung Patients and Their Families
This study aims to describe and measure the effectiveness of partnership-based nursing care for people with Chronic Obstructive Pulmonary Disease (COPD) and their families.
- Conditions
- Chronic Obstructive Pulmonary Disease, Family, Chronic Disease
- Trial name
- NCT04008862
- Testing
- Partnership-based nursing practice
- Where
- Iceland
- Volunteers
- 60 people
- Sponsor
- Helga Jónsdóttir
Chronic Obstructive Pulmonary Disease
Change of Inspiratory Peak Flow in COPD
Chronic obstructive bronchitis and emphysema (COPD) are pathophysiologically characterized by inflammatory and structural changes in the lung.
- Trial name
- NCT00561886
- Testing
- Formoterol
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johannes Gutenberg University Mainz
COPD, OSA
The Effect of Exercise on Systemic Inflammation in Veterans With COPD and OSA
The overlap syndrome (OS), i.e. the association of both Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) in a single Veteran, is prevalent and associated with increased cardiovascular disease (CVD)…
- Conditions
- COPD, OSA, Home Exercise, Inflammation
- Trial name
- NCT03431103
- Testing
- Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Salem Veterans Affairs Medical Center
Chronic Obstructive Pulmonary Disorder, Chronic Obstructive Lung Disease
COPD Patient-Powered Research Network
The COPD Patient-Powered Research Network (COPD PPRN) is a patient research registry with the goal of enrolling 75,000 or more COPD patients and those at risk who are willing to share their heath information over several years…
- Conditions
- Chronic Obstructive Pulmonary Disorder, Chronic Obstructive Lung Disease, Emphysema, Chronic Bronchitis
- Trial name
- COPD PPRN (NCT02803242)
- Testing
- Patient Reported Outcomes
- Where
- United States
- Volunteers
- 75,000 people, healthy volunteers welcome
- Sponsor
- COPD Foundation
COPD, Exacerbation Copd
Exacerbations and Their Outcomes International (EXACOS International)
The aim of this study is to quantify the burden of severe AECOPD in South Korea, by investigating the association between frequency of severe AECOPD and clinical and health-care utilization outcomes.
- Trial name
- NCT05750810
- Testing
- Severe exacerbation frequency
- Where
- South Korea
- Volunteers
- 3,477 people
- Sponsor
- Joon Young Choi
COPD Exacerbation, COPD Exacerbation Acute
Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The goal of this clinical trial is to test if treatment with prehospital Non-invasive ventilation (NIV) for patients with acute respiratory failure (ARF), due to acute exacerbation of chronic obstructive pulmonary disease…
- Conditions
- COPD Exacerbation, COPD Exacerbation Acute, Noninvasive Ventilation, Emergency Medical Services
- Trial name
- PRENIV (NCT06211920)
- Testing
- Non-invasive ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Central Denmark Region
Chronic Obstructive Pulmonary Disease
Benefits and Costs of Home-based Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease
Pulmonary rehabilitation is an effective treatment for people with chronic obstructive pulmonary disease (COPD) which improves symptoms, reduces hospitalisation and lowers healthcare costs.
- Trial name
- HomeBase (NCT01423227)
- Testing
- Home-based pulmonary rehabilitation, Hospital-based pulmonary rehabilitation
- Where
- 2 sites in Australia
- Volunteers
- 144 people
- Sponsor
- La Trobe University
COPD
Music and Perceived Rate of Exertion
The aim of this study was to evaluate the effect of listening to ambient music on the perceived exertion rate during pulmonary rehabilitation for chronic obstructive pulmonary disease patients.
- Trial name
- NCT01833260
- Testing
- Music
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
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