Clinical trials: Chronic Obstructive Pulmonary
Asthma, Mastocytosis
Mast Cell Activation Test in Allergic Disease
Activation of mast cells in the immune system is known to cause allergic reactions sometimes with severe systemic symptoms. The investigators have recently developed a blood-based mast cell activation diagnostic test in which…
- Conditions
- Asthma, Mastocytosis, Mast Cell Activation Syndrome, Food Allergy
- Trial name
- NCT03406325
- Where
- Hong Kong
- Volunteers
- 19 people
- Sponsor
- Hong Kong Sanatorium & Hospital
Chronic Obstructive Pulmonary Disease
Effect of Oral Feeding on Patients With Chronic Obstructive Pulmonary Disease
This is a prospective, randomized controlled clinical trail that involved patients with Chronic Obstructive Pulmonary Disease.The goal of this clinical trial is to compare the clinical effect of Oral Tubes vs Nasogastric Tubes in…
- Trial name
- NCT06505876
- Testing
- Basic treatment, Oral Tube Feeding, Nasogastric Tube Feeding
- Volunteers
- 80 people
- Sponsor
- Chao Phya Abhaibhubejhr Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD
Randomized,double-blind,multicenter,multinational,parallel-group,Phase III study to demonstrate the superiority of the triple fixed combination of beclometasone + formoterol + glycopyrrolate (BDP/FF/GB) administered via…
- Trial name
- TRILOGY (NCT01917331)
- Testing
- Beclometasone/Formoterol/Glycopyrrolate, Beclometasone/Formoterol
- Where
- Hungary
- Volunteers
- 1,368 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Pharyngitis, Acute Tonsillitis
Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies
The general hypothesis is that delayed antibiotic treatment strategies present similar effectiveness, when compared with non-prescription of antibiotics or the prescription of antibiotics, in the non-complicated acute respiratory…
- Conditions
- Pharyngitis, Acute Tonsillitis, Rhinosinusitis, Acute Bronchitis
- Trial name
- PDA (NCT01363531)
- Testing
- Antibiotic prescription strategies
- Where
- Spain
- Volunteers
- 405 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Diabetes, Diabetes Mellitus, Type 1
Safety of Inhaled Human Insulin in Subjects With Diabetes Mellitus and Chronic Obstructive Pulmonary Disease (COPD)
This trial is conducted in Europe, Asia and South America. A one-year clinical trial to compare the safety of inhaled human insulin to subcutaneous insulin aspart in subjects with type 1 or type 2 diabetes and chronic obstructive…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Chronic Obstructive Pulmonary Disease
- Trial name
- iINHALE 8 (NCT00472953)
- Testing
- inhaled human insulin, insulin aspart
- Where
- 27 sites in Argentina, India and 5 more
- Volunteers
- 38 people
- Sponsor
- Novo Nordisk A/S
Chronic Bronchitis, COPD
Pulmonary Function Changes in 10 Pack Year Smokers With Chronic Bronchitis
To determine whether an average population of males and females who smoke 10 pack years or more of cigarettes in a primary care setting with chronic bronchitis has already developed significant changes on pulmonary function…
- Trial name
- NCT00454675
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Westside Family Medical Center, P.C.
Chronic Obstructive Pulmonary Disease
Randomized, Double-blind, Placebo-controlled, Multicenter, Cross-over Study to Assess the Effects of a 3 Week Therapy Each With QVA149 Versus Placebo on Pulmonary Function and Average Physical Activity Levels in Patients With COPD.
This study is designed to assess the effect of QVA149 (110/50 ug q.d.) versus placebo on pulmonary function and average physical activity levels in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- MOVE (NCT01996319)
- Testing
- QVA149
- Where
- 30 sites in Germany
- Volunteers
- 194 people
- Sponsor
- Novartis Pharmaceuticals
Metabolomics, Omega 6
The Research of Metabolomics on COPD
Targeted metabolomics research was conducted on patients with chronic obstructive pulmonary disease (COPD). The correlation analyst between inflammation-related metabolites and lung function was analyzed by explored the metabolic…
- Conditions
- Metabolomics, Omega 6, Omega 3, COPD
- Trial name
- COPD (NCT04042519)
- Testing
- Lung function test was performed on the subjects with Jaeger lung function instrument of Germany., Agilent 1290 Infinity LC system (UHPLC, Santa Clara CA) was used for Targeted metabolite detection., Routine blood test
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Chronic Obstructive Pulmonary Disease
Patient-Ventilator Interactions in Chronic Obstructive Pulmonary Diseases (COPD) Under Non-Invasive Ventilation
Non-invasive ventilation (NIV) in severe hypercapnic Chronic Obstructive Pulmonary Diseases (COPD) may be associated - during sleep - with recurrent episodes of patient ventilatory asynchrony, which in turn may affect quality of…
- Trial name
- NCT01180439
- Testing
- Adjustment of ventilator settings (device)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Ligue Pulmonaire Genevoise
Chronic Obstructive Pulmonary Disease Exacerbation
The CATALINA Study
The CATALINA study is a prospective cohort study embedded within CICERO (Collaboration In COPD ExaceRbatiOns, a European Respiratory Society supported Clinical Research Collaboration), designed to collect standardised…
- Trial name
- NCT05008081
- Where
- 22 sites in Austria, Belgium and 9 more
- Volunteers
- 1,000 people
- Sponsor
- Wim Janssens
Asthma
Study to Assess the Efficacy and Safety of Budesonide (PT008) in Adult Subjects With Mild to Moderate Persistent Asthma
Study to assess the efficacy and safety of four doses of budesonide inhalation aerosol (BD MDI, PT008) relative to placebo MDI in adult subjects with mild to moderate persistent asthma.
- Trial name
- NCT02105012
- Testing
- BD MDI 320 µg, BD MDI 160 µg, BD MDI 80 µg
- Where
- 41 sites in United States
- Volunteers
- 147 people
- Sponsor
- Pearl Therapeutics, Inc.
Chronic Obstructive Pulmonary Disease
Effect of Remote Physiologic Monitoring (RPM) on Outcomes in COPD Patients
This pre/post study was a retrospective analysis of unplanned hospitalization rates in a cohort of COPD subjects started on remote physiologic monitoring (RPM) at a large, outpatient pulmonary practice.
- Trial name
- NCT05518981
- Testing
- Respiratory Remote Patient Monitor (Spire Health Tag)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Spire, Inc.
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease
Uncertainty persists regarding the usefulness of incorporating inspiratory muscle training (IMT) in pulmonary rehabilitation programs for patients with chronic obstructive pulmonary disease.
- Trial name
- NCT01056081
- Testing
- Inspiratory muscle training
- Volunteers
- 19 people
- Sponsor
- Faculdade Evangelica do Parana
COPD
Effect of Physiotherapy in Hospitalized COPD Patients
Chronic obstructive pulmonary disease (COPD) impacts negatively on the balance and strength of patients. Several studies have shown that acute exacerbations (AEs) decrease, pulmonary function and survival of COPD patients, and…
- Trial name
- NCT02509299
- Testing
- Physiotherapy program 1, Physiotherapy program 2, Standard medical treatment
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Universidad de Granada
Chronic Obstructive Pulmonary Disease
Transcutaneous Electrical Diaphragmatic Stimulation and Inspiratory Muscle Training in Patients With COPD Exacerbated
Chronic Obstructive Pulmonary Disease (COPD) is characterized by chronic airflow limitation, a qualification of impairment of respiratory muscle function, including hyperinflation and muscle weakness.
- Trial name
- NCT03844711
- Testing
- Transcutaneous electrical diaphragmatic stimulation (TEDS), Inspiratory Muscle Training (IMT), Conventional physiotherapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Bronchiectasis Adult, Bronchiectasis With Acute Exacerbation
Exploring How Viral Infections Affect People With Chronic Lung Disease
Many people with chronic lung disease have disease flare-ups. It was previously believed that these were mainly caused by bacteria but recent evidence suggests that viruses could be an important trigger.
- Conditions
- Bronchiectasis Adult, Bronchiectasis With Acute Exacerbation, COPD (Chronic Obstructive Pulmonary Disease), Respiratory Infection Virus
- Trial name
- PRIVILEGE (NCT06625944)
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Imperial College London
Lung; Disease, Interstitial, With Fibrosis, Pulmonary Disease, Chronic Obstructive
Deep Learning Diagnostic and Risk-stratification for IPF and COPD
Idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), and chronic obstructive pulmonary disease (COPD) are severe, progressive, irreversibly incapacitating pulmonary disorders with modest response to…
- Conditions
- Lung; Disease, Interstitial, With Fibrosis, Pulmonary Disease, Chronic Obstructive, Artificial Intelligence
- Trial name
- DeepBreath (NCT05318599)
- Testing
- Lung auscultation, Lung ultrasound, Quality of Life's questionnaires
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Pediatric Clinical Research Platform
Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Microbiome
Prospective Cohort Study of Molecular Mechanism of Lower Respiratory Tract Microbes in Patients With AECOPD
How to reduce the rapid decline of lung function in patients with AECOPD is a clinically urgent problem to be solved. Studies have suggested that there is a bacterial flora imbalance in the lower respiratory tract of COPD…
- Trial name
- REASON (NCT04259736)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Huashan Hospital
HIV Infections, Pneumocystis Pneumonia
Pneumocystis in Pathogenesis of HIV-associated Emphysema
A. Statement of Hypotheses: HIV-infected patients have an increased incidence of emphysema compared to non-HIV-infected smokers, and it has been hypothesized that this accelerated disease progression is the result of one or more…
- Conditions
- HIV Infections, Pneumocystis Pneumonia, Emphysema, Chronic Obstructive Pulmonary Disease
- Trial name
- PACT (NCT00869544)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Pittsburgh
Bronchitis, Chronic
AVANTI - Avelox® in Acute Exacerbations of chroNic bronchiTIs
The objective of this global non-interventional study is to evaluate the impact of Acute Exacerbation of Chronic Bronchitis(AECB) on the patient and the community as well as the safety and effect of a treatment with Moxifloxacin…
- Trial name
- NCT00846911
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- 8 sites in Albania, Bosnia and Herzegovina and 6 more
- Volunteers
- 2,672 people
- Sponsor
- Bayer
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