Clinical trials: Chronic Obstructive Pulmonary
Chronic Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
This phase II trial tests how well ibrutinib works in preventing chronic graft-versus-host disease (GVHD) in patients undergoing donor (allogeneic) hematopoietic cell transplantation (HCT).
- Trial name
- NCT06271616
- Testing
- Echocardiography Test, Ibrutinib
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Dyspnea, Heart Failure
Registry of Patients With Acute Dyspnea in the Emergency Department
This is a prospective registry of patients presenting with acute dyspnea to the emergency department of the city hospital in Nuremberg.
- Conditions
- Dyspnea, Heart Failure, COPD
- Trial name
- NCT01910233
- Where
- Germany
- Volunteers
- 947 people
- Sponsor
- Klinikum Nürnberg
Chronic Obstructive Pulmonary Disease, Hypercapnia
Non-invasive Home Ventilation in Patients With Severe Hypercapnic Chronic Obstructive Pulmonary Disease
In COPD patients with chronic hypercapnic respiratory failure, the prognosis is poor and the treatment with non invasive ventilation is actually well established. However the best mode of ventilation is not well known.
- Trial name
- SOMNOVENT' (NCT03934749)
- Testing
- Non Invasive Ventilation
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Obstructive Pulmonary Disease
Effects of Non-invasive Ventilation on Rehabilitation Outcome in COPD-patients
The aim of the study is to find out if nocturnal non-invasive ventilation during pulmonary rehabilitation increases exercise capacity and quality of life more than pulmonary rehabilitation alone.
- Trial name
- NCT01384981
- Testing
- pulmonary rehabilitation
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Lung Cancer, Perioperative/Postoperative Complications
Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer
RATIONALE: Exercise may help improve lung function and lessen complications of surgery in patients with chronic obstructive pulmonary disease who are undergoing surgery for lung cancer.
- Conditions
- Lung Cancer, Perioperative/Postoperative Complications, Pulmonary Complications, Tobacco Use Disorder
- Trial name
- NCT00363428
- Testing
- exercise intervention, smoking cessation intervention, counseling intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mayo Clinic
Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of COPD
Remote Monitoring of COPD Patients Experiencing an Acute Exacerbation Through Health Evaluations Using Wearable Mobile Technology
Chronic obstructive pulmonary disease (COPD) causes about 3 million deaths annually and significantly burdens healthcare systems, costing the EU 38.6 billion euros, largely due to frequent hospitalizations triggered by acute…
- Trial name
- COPD-BREATHE (NCT06890767)
- Testing
- Wearable mobile device, CAT Questionnaire, DHRQ Questionnaire
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- David Ruttens
COPD, Asthma
Is Patients With Pulmonary Disease Benefit a Program With Yogic Exercises?
Is Yogic Exercises (12 weeks) increasing respiratory function, functional capacity and quality of life in patients with obstructive lung diseases. With follow up after 6 months.
- Trial name
- NCT02233114
- Testing
- Yogic exercises, Physiotherapy
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Chronic Obstructive Pulmonary Disease
Clinical Trial of Efficacy and Safety of Rengalin in the Treatment of Cough in Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to obtain additional data on efficacy and safety of Rengalin in the treatment of cough in patients with stable obstructive pulmonary disease
- Trial name
- NCT03159091
- Testing
- Rengalin
- Where
- 18 sites in Russia
- Volunteers
- 238 people
- Sponsor
- Materia Medica Holding
Pulmonary Disease, Chronic Obstructive
Dose Escalating Study of CCI15106 Inhalation Capsules in Healthy Subjects and Moderate Chronic Obstructive Pulmonary Disease (COPD) Patients
This study will be the first administration of CCI15106 capsules for inhalation to humans. The primary objective of the study is to investigate the safety and tolerability of single and repeat escalating doses of CCI15106 in…
- Trial name
- NCT03243760
- Testing
- CCI15106 7.5 mg capsule
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Copd, Dyspnea
Effect of Progressive Relaxation Exercıses on Dyspnea and Comfort Level in Individuals With COPD
The study is a randomised controlled experimental study conducted to examine the effect of progressive relaxation exercises on dyspnea and comfort level in individuals with chronic obstructive pulmonary disease.
- Conditions
- Copd, Dyspnea, Nursing Caries
- Trial name
- NCT06459882
- Testing
- progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Bakircay University
Chronic Obstructive Pulmonary Disease (COPD), Inflammatory Disease
Endothelial Dysfunction in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
The purpose of the study is to determine a possible association between the clinical entity of exacerbation, markers of systemic inflammation and endothelial dysfunction in patients with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Inflammatory Disease, Endothelial Dysfunction
- Trial name
- EDAECOPD (NCT01460082)
- Where
- Austria
- Volunteers
- 29 people
- Sponsor
- LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology
GVHD, Chronic, Acute Leukemia
Electronic Database for the Follow up of the ATG_FamilyStudy
Allogeneic hematopoietic stem cell transplantation (HSCT) is capable of definitive cure of acute leukemias. The most important post-transplant complication is graft vs host disease (GVHD) which can be substantially decreased by…
- Conditions
- GVHD, Chronic, Acute Leukemia, Stem Cell Transplant Complications
- Trial name
- AFF (NCT03042676)
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
COPD, COVID-19
Impact of COVID-19 on Lung Function in COPD Patients.
Background: In 2019, a novel coronavirus (SARS-COV2) was detected in Wuhan, China as a cause of acute respiratory distress syndrome (COVID-19).
- Trial name
- EspirCOVID (NCT05770440)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
COPD Received PR
Correlation Between Pulmonary Rehabilitation and TFC
To study the effects of lung rehabilitation on the heart's hemodynamic performance of patients with chronic bidirectional lung disease when performing routine and regular PR, and found that the effects of lung rehabilitation on…
- Trial name
- NCT05240989
- Testing
- pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Fu Jen Catholic University
Asthma, Chronic Inflammatory Diseases
Predictive Factors for Exacerbation Outcome in Severe Refractory Asthmatics
Asthma is a chronic inflammatory disease, affecting up to 10 % of the general population in developed countries. Corticosteroids are necessary to control symptoms, but induce adverse events sometimes intolerable.
- Trial name
- EXPRESA (NCT00721097)
- Testing
- spirometry, and blood taken
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Chronic Graft-versus-host-disease
A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD
This study will be conducted to evaluate the safety, efficacy, and pharmacokinetics of axatilimab monotherapy in Chinese participants with recurrent or refractory active chronic graft-versus-host disease after systemic therapy.
- Trial name
- NCT06843408
- Testing
- INCA034176
- Where
- 9 sites in China
- Volunteers
- 32 people
- Sponsor
- Incyte Corporation
Chronic Bronchitis
Early Mobilization With and Without Chest Physiotherapy in Chronic Bronchitis Patients.
It will be a randomized control trial study in which data are collected from hospital. A sample of 26 patients will divided into two group.
- Trial name
- NCT05646225
- Testing
- chest physiotherapy and early mobilization, early mobilization
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients
The purpose of this study is to investigate the role of the pulmonary vasculature in the development and progression of chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01941225
- Testing
- Inhaled iloprost 5.0 mcg
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Effects of High-intensity Noninvasive Positive Pressure Ventilation in AECOPD
This study aims to investigate the effects of high-intensity noninvasive positive pressure ventilation (NPPV), as compared with low-intensity NPPV, on hypercapnia, consciousness, inspiratory muscle effort, dyspnea, NPPV…
- Trial name
- NCT04044625
- Testing
- High-intensity NPPV, Low-intensity NPPV
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Beijing Chao Yang Hospital
Chronic Obstructive Pulmonary Disease
Effect of Increased Fruit and Vegetable Intake on Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is the UK's fastest growing fatal disease and is estimated to cost the health service close to £1 billion every year. Around 80,000 people in Northern Ireland suffer from COPD.
- Trial name
- DISCO (NCT00435708)
- Testing
- 5 portions fruit and vegetables/day
- Where
- United Kingdom
- Volunteers
- 81 people
- Sponsor
- Queen's University, Belfast
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