Clinical trials: Chronic Obstructive Pulmonary
COPD, Chronic Lung Disease
Does Pulmonary Rehabilitation Change Self-Selected And Maximum Sustainable Walking Speed In Patients With Lung Disease?
Exercise training has been shown to reduce breathlessness and improve the exercise tolerance of people with lung disease. However, the effect of exercise training on the walking speed selected by these people during day-to-day…
- Trial name
- NCT00781183
- Testing
- pulmonary rehabilitation
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- West Park Healthcare Centre
Chronic Graft-Versus-Host Disease (cGVHD)
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
The purpose of this study is to determine if vimseltinib is safe, tolerable and works effectively to treat adults with active moderate to severe cGVHD.
- Trial name
- NCT06619561
- Testing
- Vimseltinib
- Where
- 26 sites in United States
- Volunteers
- 48 people
- Sponsor
- Deciphera Pharmaceuticals, LLC
Stroke, Hip Fractures
Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward
The aim of this study is to investigate the effectiveness of our developed week-treatment program GAPP, on strength, balance, speed, functionality and cognition, with the main goal to achieve a better independence for activities…
- Conditions
- Stroke, Hip Fractures, Abdominal Injury, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT03109483
- Testing
- Geriatric Activation Program Pellenberg
- Where
- Belgium
- Volunteers
- 111 people
- Sponsor
- KU Leuven
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects
GW642444 and GSK233705 are in development for treatment of Chronic Obstructive Pulmonary Disease. Development of these two inhaled drugs as a combination therapy would have potential for improved patient benefit as they both work…
- Trial name
- NCT00783003
- Testing
- GSK233705 and GW642444, GW642444, GSK233705
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease (COPD)
Study to Demonstrate That Antibiotics Are Not Needed in Moderate Acute Exacerbations of COPD
The ultimate goal is to reduce unnecessary antibiotic prescriptions which drive the development of antibiotic resistance in the community.
- Trial name
- NCT01892488
- Testing
- Sultamicillin
- Where
- 32 sites in Germany
- Volunteers
- 295 people
- Sponsor
- Hannover Medical School
Chronic Graft-versus-host Disease, Chronic GVHD
Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease
This research study is evaluating the feasibility and acceptability of implementing a telehealth palliative care intervention in patients with moderate to severe chronic graft-versus-host disease.
- Conditions
- Chronic Graft-versus-host Disease, Chronic GVHD, cGVHD
- Trial name
- cGVHDTele-PC (NCT06458127)
- Testing
- Tele-palliative care visit
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Postural Control in Chronic Obstructive Pulmonary Disease
Postural control impairment is common in people with COPD (pwCOPD), which can increase the risk of falls and affect quality of life.
- Trial name
- NEUROTIGUE P (NCT06863246)
- Testing
- Evaluation of cognitive task on static balance, Evaluation of visual feedback on static balance
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Pneumonia, Diabetes
Social Incentives to Increase Mobility
This study aims to assess the effectiveness of a social incentive-based gamification intervention to increase physical activity in the 3 months after hospital discharge.
- Conditions
- Pneumonia, Diabetes, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- MOVE IT (NCT03321279)
- Testing
- Social Incentive
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- University of Pennsylvania
Breathing Technique
Effects of BBT Versus Diaphragmatic Breathing on Exercise Capacity and Quality of Life in Patients With COPD
Group A will be treated with manual chest physical therapy and Buteyko breathing technique Group-B will be treated with manual chest physical therapy and Diaphragmatic breathing technique.
- Trial name
- NCT05947227
- Testing
- Buteyko breathing technique, Diaphragmatic breathing technique.
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease, Dyspnea
Opioids for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease
Breathlessness, the sensation of breathing discomfort, is a major problem in people with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02455362
- Testing
- Morphine sulfate
- Sponsor
- Flinders University
Sarcopenic Obesity, COPD
A Prognostic Model for COPD Complicated With Sarcopenic Obesity Based on Bioelectrical Impedance Phase Angle Technology
This study aims to explore the diagnosis, impact, and prognostic factors of COPD complicated with sarcopenic obesity using multi-segment bioelectrical impedance phase angle technology.
- Trial name
- NCT07136246
- Testing
- InBody S10
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Pulmonary Disease, Chronic Obstructive
Bayis Ilh Tus - A Strong Breath: Prevalence and Contributors to COPD in First Nations Communities in British Columbia
Background. First Nations peoples in Canada carry an increased respiratory health burden compared to non-First Nations. However, there is little accurate information of how many First Nations people have COPD, especially in…
- Trial name
- ASB (NCT04105088)
- Where
- Canada
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Graft-versus-host Disease
Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD
This study suggested that hydrogen has a potential as an effective and safe therapeutic agent on cGVHD.
- Trial name
- NCT02918188
- Testing
- Hydrogen
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Navy General Hospital, Beijing
Coronary Artery Disease, Arterial Stiffness, Blood Pressure
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018.
- Conditions
- Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency
- Trial name
- SCAPIS-ReEx (NCT07476703)
- Testing
- Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography
- Where
- Sweden
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Asthma
Clinical Assessment of Acupuncture for the Treatment of Chronic Asthma
The purpose of this study is to assess whether acupuncture is effective in the treatment of chronic asthma.
- Trial name
- NCT01931696
- Testing
- Verum acupuncture
- Where
- 12 sites in China
- Volunteers
- 200 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease (COPD)
Tiotropium Handihaler vs. Tiotropium Respimat in COPD
The purpose of this study is to determine if tiotropium Respimat will result in better ventilation distribution of the lung in COPD participants quantified by hyperpolarized XeMRI.
- Trial name
- NCT05838703
- Testing
- tiotropium bromide inhalation powder (Spiriva HandiHaler), tiotropium bromide (Spiriva Respimat), Hyperpolarized 129XeMRI
- Sponsor
- Duke University
Hypoxemia, Gastric Cancer (Diagnosis)
High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary Disease
Hypoxemia is the most common adverse event during propofol sedation for gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease (COPD) due to diminished pulmonary reserve.
- Conditions
- Hypoxemia, Gastric Cancer (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD), Esophageal Cancer
- Trial name
- NCT07791979
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhejiang University
Chronic Obstructive Pulmonary Disease
Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients (HomeBFR-COPD)
The primary aim of this randomised controlled trial is to investigate the feasibility and acceptability of low-intensity exercise with blood flow restriction (BFR) in patients with Chronic Obstructive Pulmonary disease (COPD).
- Trial name
- HomeBFR-COPD (NCT05984823)
- Testing
- Home based body weight type exercises with blood flow restriction, Home based body weight type exercises
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Mrs Hanoof Aljohani
Chronic Obstructive Pulmonary Disease
Involvement of Nervous System in Muscle Weakness in COPD Patients
The purpose of this study is to determine whether nervous system alterations and motor drive failure can contribute to muscle weakness in COPD during voluntary movement.
- Trial name
- DesCoM-1 (NCT01679782)
- Where
- France
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- 5 Santé
COPD
High Risk Populations Among COPD Patients in Japan
The patients with complications of COPD and asthma have features mixed with two diseases, COPD and asthma. Therefore, the outcomes are worsened if the patients with COPD have symptoms overlapped with asthma, however, no…
- Trial name
- NCT02413359
- Where
- Japan
- Volunteers
- 1,016 people
- Sponsor
- AstraZeneca
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