Clinical trials: Chronic Obstructive Pulmonary Disease, completed
Low Back Pain
ED Physical Therapy for Chronic Low Back Pain
Emergency department (ED)-initiated physical therapy is a rapidly growing resource and represents a promising treatment approach to low back pain.
- Trial name
- NCT05206630
- Testing
- ED Physical Therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Northwestern University
Lung Diseases, Lung Diseases, Obstructive
Clinical Study of Intermittent Positive Pressure Breathing (IPPB)
To evaluate the efficacy of long-term intermittent positive pressure breathing (IPPB) treatment when used as an adjunct to the overall care of ambulatory outpatients with chronic obstructive pulmonary disease.
- Conditions
- Lung Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00000565
- Testing
- intermittent positive-pressure breathing
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Obstructive Pulmonary Disease (COPD)
Effects of CPAP Level on Respiratory Mechanics and Central Drive in Patients With COPD
Chronic Obstructive Pulmonary Disease (COPD) is a common respiratory disease characterized by airflow limitation that is progressive and not fully reversible.
- Trial name
- NCT02285400
- Testing
- CPAP level
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhujiang Hospital
Chronic Hepatitis C
Effect of Teleprevir in Triple Therapy on Intrahepatic Immunological Mechanisms
Chronic hepatitis C infection (HCV) is a disease that affects worldwide about 170 million people. The previous standard of care therapy of chronic HCV patients consists of pegylated-IFN-α combined with ribavirin, and results in…
- Trial name
- ETIM (NCT01641094)
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Foundation for Liver Research
COPD
The Effect of Oxygen Therapy With Airvo High-flow Heated Humidification
The purpose of our study is to establish whether domiciliary use of the Airvo warm passover humidifier can reduce the number of exacerbations in patients with respiratory insufficiency.
- Trial name
- HHCOPD (NCT02731872)
- Testing
- Airvo humidifier
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Birgitte Schantz Laursen
Chronic Obstructive Pulmonary Disease (COPD)
Tolerability/Safety and Efficacy of Inhaled AZD4818 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to see if treatment with AZD4818 for four weeks is tolerable, safe and effective in treating COPD and, if so, how it compares with placebo.
- Trial name
- TOP (NCT00629239)
- Testing
- AZD4818
- Where
- 12 sites in Denmark, Finland and 3 more
- Volunteers
- 65 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Music During Pulmonary Rehabilitation for Patients With COPD
This study is aimed at determining whether listening to music during exercise will improve health-related outcomes for individuals with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02980575
- Testing
- Music, Exercise
- Where
- 2 sites in Australia, Canada
- Volunteers
- 58 people
- Sponsor
- West Park Healthcare Centre
Pulmonary Disease, Chronic Obstructive
Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients.
This is a randomised, double-blind, double-dummy, multinational, multicentre, parallel group trial comparing tiotropium (18 mcg) inhalation capsule via HandiHaler and salmeterol (50 mcg) via MDI in patients with COPD.
- Trial name
- NCT00563381
- Testing
- Tiotropium bromide, Salmeterol
- Where
- 752 sites in Austria, Belgium and 23 more
- Volunteers
- 7,376 people
- Sponsor
- Boehringer Ingelheim
Lower Respiratory Tract Infections, Community Acquired Pneumonia (CAP)
Lower Respiratory Tract Infections Managed in Primary Care in France
Primary aim: To describe participant characteristics at the time of the index lower respiratory tract infection (LRTI) episode in adults managed in primary care in France, using anonymized electronic health records from routine…
- Conditions
- Lower Respiratory Tract Infections, Community Acquired Pneumonia (CAP), Acute Bronchitis, Acute Exacerbation Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07416266
- Volunteers
- 230,066 people
- Sponsor
- Hôpital Raymond Poincaré
COPD
COPD Pal Phase 1: A Self-management App in COPD
Chronic Obstructive Pulmonary Disease (COPD) is a widespread condition which causes a poorer health status, reduced exercise, and lung function impairment.
- Trial name
- NCT04142957
- Testing
- COPD Pal
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Hywel Dda Health Board
Asthma
Montelukast Asthmatic Smoker Study (0476-332)(COMPLETED)
This is a multicenter study to evaluate the efficacy and safety of MK0476 versus placebo in participants with chronic asthma who actively smoke cigarettes.
- Trial name
- NCT00284856
- Testing
- montelukast sodium, Comparator: fluticasone
- Volunteers
- 1,640 people
- Sponsor
- Organon and Co
Chronic Obstructive Pulmonary Disease
Short Chain Fatty Acid Metabolism in COPD
The short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare the SCFA metabolism in COPD patients to healthy matched controls.
- Trial name
- SCFA (NCT03327181)
- Testing
- short chain fatty acid tracers
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Asthma, Reactive Airway Disease
Comparison of Asthma Programs for Schools
The purpose was to evaluate effectiveness and impact of an academic and counseling asthma health education program (SHARP) for fourth- and fifth-grade students diagnosed with asthma.
- Trial name
- CAPS (NCT01625364)
- Testing
- SHARP program, Open Airways for Schools
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Pulmonary Disease, COPD
The Virtual Reality Therapy as a Pulmonary Rehabilitation Supporting Method
This study evaluates the effectiveness of virtual reality (VR) therapy in the treatment of depression and anxiety symptoms in patients undergoing the pulmonary rehabilitation.
- Conditions
- Pulmonary Disease, COPD, Anxiety State, Stress
- Trial name
- NCT04601545
- Testing
- Pulmonary rehabilitation, Virtual therapeutic support
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Pulmonary Disease, Chronic Obstructive
Prevalence of Different Haptoglobin Phenotypes in Patients With COPD- Frequent Exacerbators Versus Non Exacerbators
Chronic obstructive pulmonary disease (COPD) is a common disease in smokers. COPD has a slowly deteriorating course, punctuated by exacerbations- acute events characterized by increasing shortness of breath and putrid sputum.
- Trial name
- NCT01745419
- Where
- Israel
- Volunteers
- 105 people
- Sponsor
- Carmel Medical Center
COPD
Study to Evaluate the Efficacy and Safety of Glycopyrronium or Indacaterol Maleate and Glycopyrronium Bromide Fixed-dose Combination Regarding Symptoms and Health Status in Patients With Moderate COPD Switching From Treatment With Any Standard COPD Regimen
The main goal of this study is to evaluate the efficacy and safety of glycopyrronium bromide and indacaterol maleate and glycopyrronium bromide fixed dose combination (FDC) in patients with moderate COPD who switch from their…
- Trial name
- NCT01985334
- Testing
- Glycopyrronium, SABA, LABA
- Where
- 542 sites in Austria, Belgium and 21 more
- Volunteers
- 4,389 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Effects of Breathing Retraining in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Conventional pulmonary rehabilitation programs improve exercise tolerance, peripheral muscle strength, and health related quality of live but not pulmonary function in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT01175265
- Testing
- respiratory biofeedback
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital, Essen
COPD, Chronic Obstructive Pulmonary Disease
GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary Disease) Screening?
This is a multicenter observational prospective study in smokers or ex-smokers with cumulative exposure ≥ 10 a / p (years / pack) with respiratory symptoms and presenting a normal spirometry.
- Trial name
- NCT05016466
- Testing
- Standard Care, Standard Care plus oxidative stress study plus inflammation biomarkers study
- Where
- Spain
- Volunteers
- 236 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
COPD Exacerbation
Stratified TreAtment to Reduce Risk in COPD
To evaluate the efficacy of blood-eosinophil directed corticosteroid therapy using near-patient testing, compared to current standard practice during an exacerbation of COPD in a multi-centre randomised placebo controlled trial.
- Trial name
- STARR2 (NCT04458636)
- Testing
- Prednisolone
- Where
- United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Oxford
Chronic Obstructive Pulmonary Disease
Education Impact on Rehabilitation of Hospitalized Patients with Chronic Obstructive Pulmonary Disease.
The planned research will enable the assessment of rehabilitation's effects using two pulmonary rehabilitation models: conventional and supplemented with an education program for patients hospitalized due to chronic obstructive…
- Trial name
- NCT06028711
- Testing
- Education program, Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Rzeszow
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