Clinical trials: Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients.
Background: Chronic obstructive pulmonary disease (COPD) is a common lung disease causing restricted airflow and breathing problems. It is sometimes called emphysema or chronic bronchitis.
- Trial name
- NCT07805330
- Testing
- Resistance Exercise without tourniquet, Blood flow restriction resistance exercise
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rashid Latif Medical College
Pulmonary Emphysema
Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)
The purpose of this study is to demonstrate the safety and efficacy of AeriSeal System treatment plus optimal medical therapy compared in patients with advanced upper lobe predominant (ULP) heterogeneous emphysema.
- Trial name
- ASPIRE (NCT01449292)
- Testing
- Treatment plus Optimal Medical Therapy, Optimal Medical Therapy
- Where
- 40 sites in United States, France and 5 more
- Volunteers
- 300 people
- Sponsor
- Aeris Therapeutics
COPD
A Trial to Evaluate the Efficacy and Safety of Formoterol Fumarate in the Treatment of Patients With COPD
The purpose of this study is to determine the safety and efficacy of the investigational drug in comparison with a placebo.
- Trial name
- NCT00215436
- Testing
- Formoterol Fumarate
- Where
- 44 sites in United States
- Volunteers
- 345 people
- Sponsor
- Dey
Chronic Obstructive Pulmonary Disease
Safety, Preliminary Pharmacokinetics and Bronchodilator Properties of V0162
Pulmonary administered anticholinergic agents have shown their importance in the chronic obstructive pulmonary disease (COPD) management to reduce morbidity, disability and mortality.
- Trial name
- NCT01348555
- Testing
- Bronchodilatator
- Where
- 2 sites in Belgium, France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Medicament
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Oxygen Supplementation on Cerebral Oxygenation, Symptoms and Performance During STST in COPD Patients
It is a randomised, single-blind trial of the effect of acute oxygen supplementation on cerebral oxygenation during the 30 sec Sit-To-Stand Test (STST) in chronic obstructive pulmonary disease patients, without resting hypoxemia.
- Trial name
- NCT07024914
- Testing
- Oxygen, medical air
- Where
- Greece
- Volunteers
- 25 people
- Sponsor
- George Papanicolaou Hospital
COPD, Cancer
Patient-centred Integrated Palliative Care Pathways in Advanced Cancer and Chronic Disease
Rationale: Palliative care integration in treatment pathways, palliative care networks and institutional collaborations in health services delivery seems a promising approach reducing fragmentation and discontinuity.
- Conditions
- COPD, Cancer, Heart Failure
- Trial name
- InSup-C (NCT02175147)
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 576 people
- Sponsor
- Radboud University Medical Center
Pulmonary Disease, Chronic Obstructive
Effect of Spiriva® on Health-related Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients Who Stopped Smoking During Treatment.
Post marketing Surveillance to gain insights into the effects of therapy with Spiriva® (tiotropium bromide) on health-related quality of life in COPD patients who stopped smoking during treatment and to obtain safety data…
- Trial name
- NCT02172547
- Testing
- Spiriva
- Volunteers
- 10,821 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
The Effect of Statins in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a condition of the lungs which results in breathing difficulties due to the lungs becoming inflamed and the airways narrowed.
- Trial name
- NCT01151306
- Testing
- Simvastatin, Lactose tablet
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Nottingham
Emphysema, COPD
Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT)
This is a prospective, open-label, multi-center, single-arm study to be conducted at up to 20 investigational sites. The Study plans to enroll up to 140 subjects with severe emphysema and collateral ventilation in the target…
- Conditions
- Emphysema, COPD, Severe Emphysema
- Trial name
- CONVERT (NCT04559464)
- Testing
- AeriSeal, Zephyr Valves
- Where
- 14 sites in Australia, France and 5 more
- Volunteers
- 102 people
- Sponsor
- Pulmonx Corporation
COPD, Pulmonary Hypertension
The Safety and Efficiency of Sildenafil in the Treatment of Severe Post-capillary Pulmonary Hypertension Caused by COPD
Over half of chronic obstructive pulmonary disease (COPD) patients develop pulmonary hypertension. The current therapy focuses only on the basic disease and there are a lot of controversies about the use of PAH target therapy in…
- Trial name
- NCT03185364
- Testing
- Sildenafil Citrate
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
COPD Exacerbation, Trauma
FreeO2 PreHospital - Automated Oxygen Titration vs Manual Titration According to the BLS-PCS
Evaluation of automated oxygen titration in comparison with manual adjustment oxygen in the out-of-hospital setting by paramedics.
- Trial name
- NCT03696563
- Testing
- Automated oxygen administration - FreeO2, Standard administration of oxygen flow
- Volunteers
- 100 people
- Sponsor
- François Lellouche
Asthma,, Chronic Obstructive Pulmonary Disease
Observational Study to Evaluate the Correctness of the Use of Inhaler Device in Patients With Asthma or Chronic Obstruct
The correct use of inhalation devices is an inclusion criterion for all studies comparing inhaled treatments. In real life, however, patients may make many errors with their usual inhalation device, which may negate the benefits…
- Trial name
- NCT01426893
- Where
- 5 sites in Serbia
- Volunteers
- 310 people
- Sponsor
- AstraZeneca
Asthma-COPD Overlap Syndrome, Vitamin D Deficiency
Impact of Vitamin D3 Administration on Cardiac Autonomic Tone in Asthma Chronic Obstructive Pulmonary Disease(COPD) Overlap Patients
Title:Impact of vitamin D administration on cardiac autonomic tone in Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap patients: A blinded randomized control trial.
- Conditions
- Asthma-COPD Overlap Syndrome, Vitamin D Deficiency, Cardiac Autonomic Tone
- Trial name
- COPD (NCT03773809)
- Testing
- Vitamin D capsule
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Pulmonary Disease, Chronic Obstructive
Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in COPD
Non-inferiority of lung function response to Tiotropium inhalation solution compared to Spiriva HandiHaler
- Trial name
- NCT00239447
- Testing
- Tiotropium, HandiHaler, Respimat SMI
- Where
- 11 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Boehringer Ingelheim
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Cough, Asthma
Azithromycin and Oesophageal Function in Respiratory Disease
Symptoms such as cough, wheeze, and breathlessness are among the most common reasons for general practitioner or emergency department visits in the UK.
- Conditions
- Cough, Asthma, Copd, ILD
- Trial name
- NCT05469555
- Testing
- High Resolution Oesophageal Manometry
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
COPD, COPD Bronchitis
NBMI - Clinical Study on COPD
A pilot study to explore safety of the treatment with the antioxidant and metal chelator NBMI in COPD patients. Investigational product: NBMI ((N1,N3-bis(2-mercaptoethyl) isophthalamide), INN: Emeramide Indication: Mild, moderate…
- Trial name
- Emera003COPD (NCT03123692)
- Testing
- Emeramide
- Volunteers
- 12 people
- Sponsor
- EmeraMed
Pulmonary Disease, Chronic Obstructive
Treatment Of Partial Reversible Chronic Obstructive Pulmonary Disease
Relatively little information is available about the effects of salmeterol/fluticasone combination and fluticasone alone in COPD patients with a partial reversible pulmonary obstruction.
- Trial name
- NCT00549146
- Testing
- fluticasone propionate/salmeterol 250/50 DISKUS combination product, fluticasone propionate DISKUS 500mcg
- Where
- 17 sites in Netherlands
- Volunteers
- 290 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Modulation of Dyspnea Perception During Exercise in COPD Patients Using Attentional Distraction
Chronic obstructive pulmonary disease (COPD) is a major health problem whose prevalence is increasing rapidly. The gradual decrease in exercise tolerance is one of the usual consequences of COPD that affects the functional…
- Trial name
- DVD (NCT01902927)
- Testing
- Attentional distraction using IAPS protocol (standardized images)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease (COPD)
Translating The GOLD COPD Guidelines Into Primary Care Practice
This project will evaluate the translation of the Gold (the Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease) COPD guidelines into primary care practice.
- Trial name
- LungAge (NCT01237561)
- Testing
- provider support tools plus spirometer
- Where
- United States
- Volunteers
- 3,593 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.