Clinical trials: Chronic Obstructive Pulmonary Disease (COPD)
Mechanical Power
Mechanical Power As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients :Prospective Cohort Study.
The primary objective is to evaluate the mechanical power as a predictor of weaning of mechanical ventilation in COPD patients hospitalized in the respiratory intensive care unit of Assiut University Hospital The secondary…
- Trial name
- NCT06493929
- Testing
- Chest ultrasound, Calculation of Mechanical Power on the first day of intubation and before First trial of weaning:
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
COPD
Peak Inspiratory Flow Rates in Patients With COPD
Recent studies have reported that some Chronic Obstructive Pulmonary Disease (COPD) patients may have a suboptimal ability to generate a sufficient inspiratory effort to achieve adequate lung delivery of inhaled medications…
- Trial name
- NCT04168775
- Testing
- Home PIFR monitoring with InCheck Dial
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma, COPD
Bioequivalence Study to Assess Systemic Exposure of FP and SAL FDC From Different DPIs
This is a crossover study to assess the systemic pharmacokinetics of fluticasone propionate (FP) and salmeterol (SAL). Study medication will be administered as fixed dose combinations (250 µg FP and 50 µg SAL) from the Advair®…
- Trial name
- NCT02215122
- Testing
- MGR001, Advair® Diskus®, Seretide™ Accuhaler™
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mylan Pharma UK Ltd.
Chronic Obstructive Pulmonary Disease
Characterization of Variable MARrcha's Diary Variables as a Useful Measure
Validate a simple clinical tool to evaluate physical activity (the question "How many minutes does it walk per day?" Or equivalent), compared to the rest of the collected physical activity data (PROactive questionnaire and…
- Trial name
- NCT03942302
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Ferran Morell
Chronic Obstructive Pulmonary Disease
A Scintigraphy Study of PT010 in COPD Patients
This study is a single treatment period, single dose gamma scintigraphy study investigating the deposition in the lungs of a Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dose Inhaler (BGF-MDI).
- Trial name
- RD708/34000 (NCT03906045)
- Testing
- BGF-MDI
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive (COPD)
Additional Effects of Box Breathing Technique With Short Term Pulmonary Rehabilitation on Dyspnea and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease is progressive and irreversible respiratory condition characterized by persistent airflow limitation leading to dyspnea and reduced functional capacity.
- Trial name
- NCT07518472
- Testing
- Short term Pulmonary Rehabilitation, Box breathing with short term pulmonary rehabilitation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Chronic Obstructive Pulmonary Disease, Exacerbation Copd
15-year Mortality After Hospitalization for Exacerbation of Chronic Obstructive Pulmonary Disease
The investigators examine the 15-year mortality after an admission for an exacerbation of Chronic Obstructive Pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Exacerbation Copd, Mortality
- Trial name
- MORTCOP (NCT02972775)
- Testing
- no interventions. observational study
- Where
- Netherlands
- Volunteers
- 845 people
- Sponsor
- Zuyderland Medisch Centrum
Pulmonary Disease, Chronic Obstructive
The Effect of Mobile Health Applications on Symptom Control, Self-efficacy and Chronic Disease Management in COPD
Name:The effect of the mobile application developed to provide symptom control in chronic obstructive pulmonary patients on self-efficacy and chronic disease management Aim:Considering the covid-19 pandemic seen all over the…
- Trial name
- NCT05295901
- Testing
- mKOAH application
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Chronic Obstructive Pulmonary Disease
Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD
Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest.
- Trial name
- NCT01173328
- Testing
- Pursed-lip breathing, Normal Breathing
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Rio de Janeiro
COPD
Monitoring Chronic Obstructive Pulmonary Disease Patients at Home by a Forced Oscillation Technique Device
Chronic obstructive pulmonary disease (COPD) is a pathological condition whose progression is characterized by stable periods broken up by intermittent acute exacerbations of the symptoms, during which a severe inflammatory…
- Trial name
- NCT01552031
- Where
- 5 sites in Australia, Italy
- Volunteers
- 80 people
- Sponsor
- Raffaele Dellaca
COPD
Study to Evaluate the Impact of the "PROactive Telecoaching Program" on Physical Activity in Patients With COPD.
This study will test two instruments to measure physical activity in COPD patients: A questionnaire and two small physical activity monitors .Patients will be randomized to either receive the telecoaching program in addition to…
- Trial name
- PROactive (NCT01992081)
- Testing
- Automated telehealth system, Usual care
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen.
The main purpose of this study is to determine the effect of Losmapimod on blood vessels in patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- EVOLUTION (NCT01541852)
- Testing
- Losmapimod
- Where
- 2 sites in United Kingdom
- Volunteers
- 72 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Chronic Obstructive Pulmonary Disease
Education With Inhalers in Patients With COPD Exacerbation
Chronic obstructive pulmonary disease (COPD) is a public health problem with great morbidity. The main therapeutic strategy is inhalers.
- Trial name
- NCT03337958
- Testing
- Ventilatory re-education
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Universidad de Granada
Copd, Smoking
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco.
- Conditions
- Copd, Smoking, Tobacco Use
- Trial name
- Pre-COPD Pilot (NCT04722835)
- Testing
- Bronchoscopy with Bronchoalveolar Lavage (BAL)
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Severe Asthma, COPD
Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease
In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with muco-obstructive pulmonary disease.
- Conditions
- Severe Asthma, COPD, Non-CF Bronchiectasis, Cystic Fibrosis (CF)
- Trial name
- NCT06985225
- Testing
- Hyperpolarized 129 Xenon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Kansas Medical Center
Chronic Obstructive Pulmonary Disease
The Chronic Obstructive Pulmonary Disease Fish Oil Pilot Trial
Chronic obstructive pulmonary disease (COPD) is currently the fourth leading cause of death in the United States. Unlike the other leading causes of death, no medical therapies currently available improve the course of disease or…
- Trial name
- COD-Fish (NCT00835289)
- Testing
- n-3 polyunsaturated fatty acids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
Reactive Airway Disease, Wheezing
Nasal Findings in Reactive Airway Diseases
Reactive airway diseases is a common respiratory diseases affecting 1-18% of the population in different countries. It carries a significant burden to children, their families, the healthcare system and the overall community.The…
- Trial name
- nasalfinding (NCT03131323)
- Testing
- • Flexible fiberopticnasopharyngoscope
- Volunteers
- 50 people
- Sponsor
- Assiut University
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Early Warning System
The study will begin in 2013 whereby patients having an early warning system (EWS) alert will be randomized to be seen by the rapid response team (RRT) for triage versus usual care.
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cancer, Diabetes Mellitus
- Trial name
- NCT01741480
- Testing
- Early warning system monitoring., routine care
- Where
- United States
- Volunteers
- 571 people
- Sponsor
- Washington University School of Medicine
COPD, Chronic Obstructive Pulmonary Disease
Comparison of 3-Minute Step Test (3MStepT) and 6-Minute Walk Test (6MWT) in COPD Patients
The aim of this study is to compare oxygen desaturation during two tests: the 6 minute walk test and the 3 minute step test, for COPD patients.
- Trial name
- NCT02873780
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier des Pays de Morlaix
Chronic Obstructive Pulmonary Disease
Computed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in Chronic Obstructive Pulmonary Disease (COPD) Patients
In this study, 20 COPD patients will undergo a high-resolution/multi slice CT scan and lung function tests to obtain patient specific geometries of the central and peripheral small airways and patient specific boundary…
- Trial name
- NCT00966459
- Testing
- Computed Tomography
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.