Clinical trials: Chronic Pain, Postoperative
Adolescent Idiopathic Scoliosis, Cerebral Palsy
Pain Assessment in Children Undergoing Spine Surgery
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain conditions have a major impact on the daily lives.
- Trial name
- NCT04244760
- Testing
- Pain assessment for verbal patients, Pain assessment for non-verbal patients
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Catherine Ferland
Cerebral Palsy
Managing Post-operative Pain in Children With Cerebral Palsy Using a Pain Pump
The purpose of this study is to determine which pain management strategy continuous analgesic pump or orally-should be used in the management of children with cerebral palsy.
- Trial name
- NCT00884650
- Testing
- oral analgesic, intravenous analgesic per pump
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Colorado, Denver
Serratus Plane Block, Postoperative Hyperalgesia
Effect of Liposome Bupivacaine Serratus Plane Block on Postoperative Hyperalgesia and Chronic Post-surgical Pain in Patients Undergoing Radical Mastectomy
Radical mastectomy is currently the mainstream surgical treatment for breast cancer. Patients often experience significant postoperative pain, and some may develop chronic pain.
- Conditions
- Serratus Plane Block, Postoperative Hyperalgesia, Chronic Post-surgical Pain, Liposomal Bupivacaine
- Trial name
- NCT07289178
- Testing
- Serratus Plane block (single injection)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Residual Limb Pain, Post-Traumatic Limb Pain
Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma
Combat-related extremity trauma frequently results in persistent pain, including neuropathic, residual limb, and phantom limb pain.
- Conditions
- Residual Limb Pain, Post-Traumatic Limb Pain, Extremity Trauma, Combat-Related Limb Injury
- Trial name
- KIN-LIMB (NCT07432685)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Postoperative Chronic Pain
Effect of Esketamine and Lidocaine on Postoperative Chronic Pain and Long-term Survival in Patients Undergoing Hepatectomy
This study is a further observation and follow-up of the patients enrolled in the registration number ChiCTR230007164430 to further evaluate the effect of long-term infusion of esketamine and lidocaine on postoperative chronic…
- Trial name
- NCT06778460
- Testing
- Esketamine-lidocaine group
- Where
- China
- Volunteers
- 304 people
- Sponsor
- West China Hospital
Breast Cancer, Breast Cancer Lymphedema
The Recovery of Reaching Movement in Breast Cancer Survivors: Two Different Rehabilitative Protocols in Comparison
This study emphasizes the importance of rehabilitation in breast cancer survivors after mastectomy, even during the course of radiotherapy and chemotherapy, both for good efficacy in reducing pain and for functional recovery of…
- Conditions
- Breast Cancer, Breast Cancer Lymphedema, Pain, Pain, Postoperative
- Trial name
- NCT04166279
- Testing
- Single rehabilitative treatment, Group rehabilitative treatment
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Back Pain, Spinal Stenosis
Perioperative ACT for Preventing CPSP
The present study aims to adapt and modify a brief perioperative Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Back Pain, Spinal Stenosis, Spondylosis, Spondylolisthesis
- Trial name
- PREPS (NCT06750874)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Samantha Meints
Post-operative Intercostal Neuralgia
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain.
- Trial name
- NCT01314482
- Testing
- Minocycline
- Where
- Australia
- Volunteers
- 116 people
- Sponsor
- University of Adelaide
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Breast Cancer Female, Postoperative Pain
Study of Lipid Mediators in Chronic Postoperative Pain - LICP
This interventional prospective study aims firstly to investigate variations in lipid levels in blood samples and their potential relationship with the duration and/or intensity of post-operative pain.
- Trial name
- LICP (NCT06907810)
- Testing
- Blood sample + questionnaire
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Université Catholique de Louvain
Chronic Postoperative Pain
euCPSP: European Observational Study on Chronic Post Surgical Pain,PAIN-OUT Study
This project a European observational study on the incidence and characteristics of chronic post surgical pain (CPSP). Research Questions What is the incidence of chronic post surgical pain (CPSP) in Europe? What are the risk…
- Trial name
- PAIN-OUT (NCT01467102)
- Where
- 24 sites in Belgium, France and 9 more
- Volunteers
- 3,618 people, healthy volunteers welcome
- Sponsor
- European Society of Anaesthesiology
Chronic Pain, Post-operative Pain
Minocycline to Reduce Pain After Carpal Tunnel Release
The investigators are looking at whether peri-operative minocycline will reduce the duration of pain after minor hand surgery: carpal tunnel release and trigger finger release.
- Trial name
- NCT02051296
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Pain, Postoperative
Observational Study of an Automatic Detection of Patients at Risk of Chronic Postoperative Pain ("Alerte Douleur")
Following surgery, some but not all patients develop persistent (or chronic) postoperative pain CPSP. Several risk factors for this persistent pain have been confirmed in previous studies, but neither surgeons nor…
- Trial name
- ALDO (NCT03164954)
- Testing
- automatic risk detection
- Where
- Switzerland
- Volunteers
- 355 people
- Sponsor
- Benno Rehberg-Klug
Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain
Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery
SPRINT PNS System will be offered to patients with postoperative knee pain following primary unilateral total knee arthroplasty (TKA) who meet eligibility criteria and consistent with established coverage policy.
- Conditions
- Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery
- Trial name
- NCT04670042
- Testing
- SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)
- Where
- United States
- Sponsor
- Stanford University
Chronic Postoperative Pain
Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention
This study will test the null hypothesis that low-dose ketamine given peri-operatively will have no effect on the development of chronic post-surgical pain, in patients undergoing thoracotomy or video assisted thoracic surgery…
- Trial name
- NCT01296347
- Testing
- Ketamine
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Imperial College Healthcare NHS Trust