Clinical trials: Chronic Pain, completed
Chronic Shoulder Pain
Central Sensitization and Functional Outcomes in Chronic Shoulder Pain
This prospective observational cohort study aims to investigate whether baseline central sensitization and psychological factors predict functional outcomes following rehabilitation in individuals with chronic shoulder pain.
- Trial name
- SHOULDER-CS (NCT07654023)
- Testing
- Physiotherapy Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Ayşenur Yılmaz
Low Back Pain
Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain
The primary objective is to assess the efficacy of oxycodone/naloxone (OXN) for the management of opioid-induced constipation (OIC) compared to oxycodone controlled-release tablets (OXY) in subjects with moderate to severe low…
- Trial name
- NCT01427270
- Testing
- Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release
- Where
- 194 sites in United States, Czechia and 2 more
- Volunteers
- 455 people
- Sponsor
- Purdue Pharma LP
Sub-acute Back Pain
Effect of L-dopa In Subacute Back Pain Population
This study aims to determine if early treatment with Carbidopa/Levodopa and Naproxen in individuals with sub-acute back pain (SBP) is associated with changes in blocking transition to chronic back pain (CBP).
- Trial name
- NCT01951105
- Testing
- Naproxen, Carbidopa/Levodopa
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Northwestern University
Neck Pain, Work-related Injury
Clinical Outcomes, Viscoelastic Properties and Central Pain Mechanisms After Eccentric Training in Neck/Shoulder Pain
Objectives: The aims are to 1) evaluate the clinical impact of eccentric training in female computer users with chronic NSP, 2) compare pressure hyperalgesia, temporal summation of pain (TSP), and conditioned pain modulation…
- Conditions
- Neck Pain, Work-related Injury, Shoulder Pain
- Trial name
- NCT03474705
- Testing
- Eccentric Training Protocol
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Seville
Postoperative Pain, Back Pain Lower Back Chronic
Magnesium Sulfate Infusion on Postoperative Pain in Lumbar Surgery
Effective postoperative analgesia after lumbar spine surgery (e.g., laminectomy, vertebroplasty, lumbar stabilization) is associated with faster recovery and shorter hospital stay.
- Trial name
- NCT07418580
- Testing
- Magnesium sulfate, normal saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Analgesia, CYP2D6 Polymorphism
Cytochrome P450's Pharmacogenomics in Chronic Pain Patients
The use of titrated drugs is at the base of a successful antalgic treatment in order to provide both an adequate relief and a satisfactory tolerability profile.
- Conditions
- Analgesia, CYP2D6 Polymorphism, Opioid Use, Chronic Pain
- Trial name
- FACIDOCRO (NCT03411759)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bologna
Cervical Pain
Instrument-assisted Soft Tissue Mobilization and Kinesiotape Application in Individuals With Chronic Neck Pain.
Chronic neck pain causes errors in joint position sense. There are studies in the literature suggesting that instrument-assisted soft tissue mobilization and Kinesiotape applications improve the joint position sense.
- Trial name
- NCT04765670
- Testing
- Instrument Assisted Soft Tissue Mobilization, Kinesiotape Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Trigger Points
Instrument Assisted Soft Tissue Mobilization Versus Trigger Points Release on Upper Trapezius Trigger Points
Study will be randomized clinical trial. Data will be collected from non probability consecutive sampling technique. Total 30 participants from Ganga Ram Hospital and Care medical centre will be selected and randomly allocated to…
- Trial name
- NCT05249660
- Testing
- Soft tissue release technique, Comparator: Instrument assisted soft tissue mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Pain
Medication Review Improves Pain Management and Quality of Life in Chronic Pain
The goal of this parallel-group, single-blinded, randomized study is to conduct Medication Review (MR) Type III in chronic non-cancer pain patients to optimize drug therapy and measure it's influence on Pain Intensity and Quality…
- Trial name
- NCT06997861
- Testing
- Medication Review Type III, Usual Care
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Polytechnic Institute of Porto
Chronic Apical Periodontitis
Adjunctive Oral Probiotics in Endodontic Retreatment: Effects on Postoperative Pain and RANKL/OPG Levels
This study aimed to evaluate the effect of oral administration of probiotics as an adjunctive treatment to local intracanal medicaments, namely propolis and calcium hydroxide or empty canal, on the levels of receptor activator of…
- Trial name
- RANKL/OPG (NCT07683520)
- Testing
- Linex Adult®, Ca(OH)2 as intracanal medicament, propolis intracanal medication
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Meralgia Paresthetica, Chronic Low-back Pain (cLBP)
Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain
This study is designed to compare the effectiveness of two physiotherapy techniques-Dry Needling and the Cyriax Technique-in people suffering from chronic low back pain (CLBP) that radiates to the outer thigh, a condition…
- Trial name
- NCT07089472
- Testing
- Dry Needling Therapy, Cyriax Technique
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
Lumbar Disc Herniation
Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation
The aim of this study is to investigate the effectiveness of pulse magnetic field therapy on pain, functional status, and quality of life in patients with chronic radicular pain due to lumbar disc herniation.
- Trial name
- NCT04049812
- Testing
- PEMF, Hot pack, TENS
- Volunteers
- 50 people
- Sponsor
- Birkan Sonel Tur
Neck Pain
Instrumental Soft Tissue Mobilization in Patients With Chronic Neck Pain
In this study, it was planned to investigate the effectiveness of instrument-assisted soft tissue mobilisation (IASTM) in patients with chronic neck pain.
- Trial name
- NCT04789265
- Testing
- instrumented- assisted soft tissue mobilization (IASTM)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ayşegül BOSTAN
Chronic Pain, Low Back Pain
Embodiment in Virtual Reality as a Telemedicine Digital Therapeutic for the Treatment of Chronic Shoulder Pain
Chronic shoulder pain is a common musculoskeletal pain condition that can have a profound impact on a sufferer's life and a large socioeconomic healthcare burden to society.
- Conditions
- Chronic Pain, Low Back Pain, Shoulder Pain
- Trial name
- NCT05375500
- Testing
- telemedicine digital therapeutic
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Chronic Pain
Animal-assisted Therapy for Children and Adolescents With Chronic Pain
Chronic pain is highly prevalent in children and adolescents, up to one in four children will develop pain that persists or recurs for three or more months.
- Trial name
- NCT04171336
- Testing
- Animal-assisted therapy
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- University Hospital, Basel, Switzerland
Knee Injuries and Disorders, Hip Injuries and Disorders
Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery
The purpose of this study is to evaluate the use of post-operative opioid use after two different educational interventions. The investigators will compare changes in pain, disability and sleep between groups 6 months after…
- Conditions
- Knee Injuries and Disorders, Hip Injuries and Disorders, Opiate Addiction
- Trial name
- OpiateLEO (NCT02997644)
- Testing
- Video Education, Usual Care Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Pain, Chronic
An Evaluation of a Public Health Campaign in a High School Setting Targeting Pain Related Knowledge and Beliefs
The beliefs held by students lead to behaviours in response to their pain which can be both helpful or a hindrance to how they manage their pain.
- Trial name
- NCT05636345
- Testing
- pain science education
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Teesside University
Neuropathic Pain
Exploring the Role of the GABAergic Modulation in Pain Transmission in Human
Neuropathic pain affects about 7% of the general population in European countries. Meta-analyses indicate that only a minority of neuropathic pain patients has adequate response to drug therapy and management of neuropathic pain…
- Trial name
- NDMC-101 (NCT03375034)
- Testing
- NDMC 20mg, NDMC60mg, Clonazepam 1.5mg
- Where
- Switzerland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Neuralgia, Complex Regional Pain Syndromes
Novel Treatment Option for Neuropathic Pain
The purpose of this study is to determine whether the EGFR-inhibitor cetuximab is better than placebo for the treatment of neuropathic pain.
- Trial name
- NoTOPain (NCT02490436)
- Testing
- Cetuximab
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Sorlandet Hospital HF
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