Clinical trials: Chronic Pain, completed
Chronic Pain
Exploring the Link Between Pain and Distress in Adolescent Patients with Chronic Pain
The primary aim is to explore what it is about the experience of chronic pain that may cause emotional distress in some young people but not in others, and how particular individual characteristics, as well as family factors may…
- Trial name
- NCT04261114
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- University of Oxford
Chronic Low Back Pain, Chronic Neck Pain
Effect of Combined Morphine and Duloxetine on Chronic Pain
A double-blind, randomized, and placebo-controlled clinical study examining whether duloxetine, a serotonin and norepinephrine reuptake inhibitor (SNRI), could enhance opioid analgesia and reduce overall opioid use.
- Trial name
- Duloxetine (NCT03249558)
- Testing
- Morphine, Duloxetine
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Massachusetts General Hospital
Neck Pain, Sleep
Evaluation of Sleep Quality in Patients With Chronic Neck Pain
This study aimed to investigate the effect of chronic neck pain on sleep quality and to determine the factors that may be related to sleep disturbance.
- Trial name
- NCT03314285
- Testing
- Sleep Quality
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Alper Mengi
Chronic Low Back Pain, Gait
Complexity & Distraction in LBP
Motor control, notably expressed through the complexity of the variability of the locomotor pattern, is disturbed at the central level by an apprehension of pain and movement, more than pain itself (or by biomechanical /…
- Conditions
- Chronic Low Back Pain, Gait, Motor Activity
- Trial name
- CoDiLoBP (NCT03633578)
- Testing
- walk test
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Opioid-induced Constipation
Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation
The purpose of this study is to evaluate the efficacy and safety of naldemedine in the treatment of opioid-induced constipation (OIC) in adults with non-malignant chronic pain who are not using laxatives.
- Trial name
- NCT01965158
- Testing
- Naldemedine
- Where
- 65 sites in United States, Austria and 5 more
- Volunteers
- 547 people
- Sponsor
- Shionogi
Central Sensitisation, Cervical Spine Stenosis
Comparison of Pain, Sensitisation, Function and Quality of Life According to Stenosis Degree in Chronic Neck Pain
The cervical spine is a structure that bears the weight of the head and has important functions, but is susceptible to mechanical stress and degenerative processes.
- Trial name
- NCT06967415
- Testing
- Pain, central sensitization,functional status and quality of life.
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Postoperative Pain, Chronic Pain
A Clinical Trial of a Psycho-educational Intervention to Improve Pain Management After Day Surgery
Evidence indicates that postoperative pain after day surgery is inadequately controlled. Patients have different experiences and knowledge about how to deal with pain, and the need for information and clarification may vary.
- Trial name
- NCT01595035
- Testing
- psychoeducational
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo Metropolitan University
Chronic, Non Malignant Pain
Open Label, Safety Study of EN3270 in Patients With Moderate to Severe Non-malignant, Chronic Pain
Two stage study looking at different titration schedules in patients with moderate to severe non-malignant chronic pain. Up to 80 patients at approximately 15 centers in the US to be enrolled.
- Trial name
- NCT00485225
- Testing
- EN3270
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Durect
Chronic Pain
Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study
This is a prospective, multi-center, randomized, single-blind, cross-over, non-significant risk IDE research study to evaluate the in-clinic performance of a closed-loop algorithm in Spinal Cord Stimulation (SCS) therapy with an…
- Trial name
- ECHO-MAC (NCT04765735)
- Testing
- Open-loop testing, Closed-loop testing - External Spinal Cord Stimulator (SCS)
- Where
- 9 sites in United States
- Volunteers
- 52 people
- Sponsor
- MedtronicNeuro
Chronic Pain
Internet-delivered ACT for Chronic Pain
The overall aim of the present study is to evaluate an internet-delivered Acceptance and Commitment therapy treatment (iACT) for patients with chronic pain.
- Trial name
- iACT (NCT03105908)
- Testing
- Internet delivered Acceptance and Commitment therapy, Waiting list control condition
- Where
- Sweden
- Volunteers
- 113 people
- Sponsor
- Rikard Wicksell
Pain, Chronic, Pain, Postoperative
Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study)
Through this quantitative, multivariate factorial experimental parallel randomized clinical trial, the investigators analyzed the effectiveness of pre-anesthetic assessment and pain neuroscience education in reducing anxiety…
- Conditions
- Pain, Chronic, Pain, Postoperative, Anesthesia, Surgery
- Trial name
- NCT05435508
- Testing
- Pain Neuroscience Education, Usual care
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Instituto Neurociencia Del Dolor
Low Back Pain
Low Back Pain Patient Education Evaluation
Back pain is one of the most common of all symptoms. It is also a great cause of days lost from work and visits to health care providers.
- Trial name
- NCT00000408
- Testing
- Patient education evaluation
- Where
- United States
- Volunteers
- 580 people
- Sponsor
- Stanford University
Chronic Pain
Pain and Loneliness
Loneliness-feeling socially isolated-is a stressor that is associated with chronic pain. The investigators will first conduct a small trial of Cognitive Behavioral Therapy for Loneliness (CBT-L)in Veterans with chronic pain…
- Trial name
- NCT05455476
- Testing
- CBT for Loneliness, CBT for Chronic Pain
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Metatarsalgia
Physiotherapy for Chronic Metatarsalgia
The pilot study was conducted in the form of an open prospective single-arm observational study with 28 patients who received physiotherapy at the Spiraldynamik® Med Center in Zurich.
- Trial name
- NCT02578615
- Testing
- physiotherapy
- Volunteers
- 28 people
- Sponsor
- Spiraldynamik AG
Tennis Elbow
ITU Treatment for Chronic Epicondylitis Musculoskeletal Pain Reduction
This study evaluates the effectiveness, safety and patient tolerance for the use of Intense Therapeutic Ultrasound (ITU) for chronic, subcutaneous lateral Epicondylitis musculoskeletal tissue pain reduction began in July 2015 and…
- Trial name
- ITU (NCT03255733)
- Testing
- Intense Therapeutic Ultrasound Treatment
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Guided Therapy Systems
Peptic Ulcer
Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450658
- Testing
- HZT-501, Ibuprofen
- Volunteers
- 627 people
- Sponsor
- Amgen
Low Back Pain
Therapeutic Effects of Horticulture on Anterior Cingulate Cortex Activation in People With Chronic Low Back Pain
Chronic low back leads to a significant socio-economic burden. It is associated with physical and psychosocial deconditioning. Even a short "nature experience" has positive effects on the affective and cognitive factors involved…
- Trial name
- HORTICARE (NCT04656158)
- Testing
- Physical activity involving exposure to nature: Therapeutic horticulture
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Severe Chronic Pain
A Study to Explore the Influence of Two Opioid Pain Medications on Bacterial Composition in the Gut and Other Gastrointestinal Aspects
The study is intended to explore changes in the composition and quantity of gut bacteria subject to treatment with strong pain medication. Two pain medications will be compared (OXN PR and OxyPR).
- Trial name
- NCT01915147
- Testing
- OXN PR followed by OxyPR tablets, OxyPR followed by OXN PR tablets
- Where
- 2 sites in Germany
- Volunteers
- 108 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Chronic Pain
Evaluation of Attachment, Self-compassion and Coping Strategies in Chronic Pain Patients
Compare the self-compassionate score by type of attachment, "safe" or "insecure", in chronic pain patients.
- Trial name
- attachpain (NCT03845816)
- Testing
- Self-Compassion Scale (SCS) questionnaire
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Fatigue, Nausea and Vomiting
Nurse-Provided Care or Standard Care in Treating Patients With Pancreatic Cancer
RATIONALE: Meeting with a nurse to assess symptoms and quality of life may be more effective than standard care in treating patients with pancreatic cancer.
- Conditions
- Fatigue, Nausea and Vomiting, Pain, Pancreatic Cancer
- Trial name
- NCT00902733
- Testing
- medical chart review, questionnaire administration, fatigue assessment and management
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- City of Hope Medical Center
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