Clinical trials: Chronic Pain Management
Low Back Pain
The Quality of Physiotherapy in Low Back Pain Patients in Central Finland
Chronic low back pain is one of the most common musculoskeletal disorders. In the Finnish Health 2000 survey the incidence of low back pain was 10% in men and 11% in women.
- Trial name
- NCT04034186
- Volunteers
- 100 people
- Sponsor
- Juhani Multanen
Chronic Insomnia, Chronic Pain
Lemborexant vs Clonidine vs Sedatives to Treat Insomnia in Chronic Pain Patients
Prospective observational crossover study of 250 adults undergoing chronic pain management. For insomnia treatment, patients alternate their usual prescribed sedative versus Lemborexant or Clonidine; on alternate nights.
- Conditions
- Chronic Insomnia, Chronic Pain, Restless Leg Syndrome (RLS), Substance Abuse
- Trial name
- NCT05618002
- Testing
- Lemborexant
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Salem Anaesthesia Pain Clinic
Chronic Pain Syndrome, Chronic Pain
Supporting Self-management of Chronic Pain
Does the Navigator Tool Intervention improve communication regarding self-management during consultations between healthcare professionals and people with chronic pain? As there is usually no cure for chronic pain, healthcare…
- Conditions
- Chronic Pain Syndrome, Chronic Pain, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- NCT03119896
- Testing
- The Navigator Tool Intervention
- Where
- 5 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Pain Concern
Chronic Pain, Opioids
I-COPE Study: Opioid Use and Pain Management in Older Adults
Adults over 65 years of age are at higher risk of experiencing chronic pain and adverse events from opioids and opioid use disorder (OUD).
- Conditions
- Chronic Pain, Opioids, Opioid-use Disorder
- Trial name
- I-COPE (NCT04878562)
- Testing
- I-COPE
- Where
- 2 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- University of Chicago
Acute Postoperative Pain, Chronic Postoperative Pain
Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to learn whether intravenous buprenorphine administered via a patient-controlled analgesia (PCA) system provides effective and safer postoperative pain control than intravenous oxycodone PCA in…
- Conditions
- Acute Postoperative Pain, Chronic Postoperative Pain, Toracosurgery, Video-assisted Thoracis Surgery (VATS)
- Trial name
- NCT07434427
- Testing
- Group B (Buprenorphine), Group O (Oxycodone)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Silesia
Chronic Pain
iACT With Pain: an ICT-delivered Intervention for Self-management of Chronic Pain
This project aims to test the effectiveness of an ICT-based delivery of an evidencebased psychological intervention for Chronic Pain (CP) - iACTwithPain.
- Trial name
- iACT (NCT04200183)
- Testing
- iACTwithPain (ACT+compassion), ACT-only intervention
- Volunteers
- 246 people
- Sponsor
- University of Coimbra
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Knee Pain Chronic, Osteoarthritis
Cryoneurolysis for TKA - a Pilot Study
Total Knee Arthroplasty (TKA) is also known as a knee replacement. It is one of the most common orthopaedic (bone) surgeries performed and is usually very successful, but some people who have had a knee replacement feel pain that…
- Trial name
- NCT05286996
- Testing
- Iovera - Cryoneurolysis, Local anesthetic
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Fibromyalgia
Elucidating the Central Mechanisms of Action for Green Light Therapy in Managing Chronic Pain
Investigators have previously shown that specific colors of light can alter nociception. Green light emitting diode exposure (GLED) provides long-lasting antinociception in rodents, through the visual system.
- Trial name
- NCT05569486
- Testing
- Green Light
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Arizona
Chronic Pain, PTSD - Post Traumatic Stress Disorder
Virtual Reality and Cranial Nerve Neuromodulation to Manage Chronic Pain
In Canada, veterans suffer from chronic pain at twice the rate of the general population. This pain is often linked to post-traumatic stress disorder (PTSD), and both have a major impact on their quality of life.
- Trial name
- VR & CN-NINM (NCT07065396)
- Testing
- Virtual reality, Cranial nerve non-invasive neuromodulation (CN-NINM)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Université de Sherbrooke
Pain Management, Autism Spectrum Disorder (ASD)
Prospective Study to Determine the Prevalence of Signs of Central Sensitization in Adults With ASD Without Intellectual Developmental Disorders
Autism is a neurodevelopmental disorder (NDD) characterized by two key features: persistent deficits in communication and social interaction, and restricted, repetitive patterns of behavior, interests, and activities.
- Trial name
- Presca (NCT07495761)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Groupe Hospitalier Mutualiste de Grenoble
Endometriosis, Chronic Pain
Evaluation of Yoga and Conventional Physical Exercise for Pain and Quality of Life in Women With Endometriosis: A Randomized Clinical Trial
two-arm randomized parallel-group trial comparing an 8-week online yoga program versus a conventional physical exercise program.
- Conditions
- Endometriosis, Chronic Pain, Dysmenorrhea, Dyspareunia
- Trial name
- NCT07424859
- Testing
- YOGA, physical exercise
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Osteoarthritis
Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability
The purpose of this study is to investigate the feasibility, effectiveness, and duration of treatment response of periosteal electro-acupuncture (osteopuncture) for osteoarthritis (OA)-associated chronic knee pain.
- Trial name
- NCT00417313
- Testing
- periosteal electro-acupuncture (osteopuncture).
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Institute on Aging (NIA)
Chronic Musculoskeletal Pain
Evaluating Chronic Pain Management Program
This interventional study seeks to evaluate the overall outcomes of a novel, integrated yoga based intervention for people with chronic musculoskeletal pain and assess the experience of patient to the self care using yoga…
- Trial name
- NCT04313309
- Testing
- Integrative Yoga Therapy
- Volunteers
- 30 people
- Sponsor
- Aarogyam UK
Chronic Low-back Pain, Older Adults
Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults
Objectives: To develop an exercise program for older adults with low back pain. And,to develop a clinical prediction rule that could identify a subgroup of people with NSLBP Participants: 150 people aged between 40 to 80 with…
- Conditions
- Chronic Low-back Pain, Older Adults, Core Stabilization Exercise Therapy
- Trial name
- NCT06030128
- Testing
- core stabilization exercise
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The Hong Kong Polytechnic University
Post Herpetic Neuralgia (PHN)
Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia
The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous auricular vagus nerve stimulation (taVNS) in the treatment of patients with post-herpetic neuralgia (PHN).
- Trial name
- NCT07123987
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS), traditional medical treatment for PHN
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mohamed Hosny Ismail Easa
Chronic Low-back Pain
Online Physical Exercise for Chronic Low Back Pain
This study aims to evaluate the effects of technology-based interventions, specifically web-based platforms, on outcomes of patients with chronic low back pain.
- Trial name
- CLBPEO (NCT05895630)
- Testing
- Interactive physical exercise, Video physical exercise
- Where
- 2 sites in Canada
- Volunteers
- 57 people
- Sponsor
- Mathieu Roy
SC Disease, Pain, Chronic
Ketamine Sickle Cell Disease
Sickle cell disease (SCD) often results in acute vaso-occlusive crisis (VOC), an obstruction of blood vessels resulting in ischemic injury and pain.
- Trial name
- SCD (NCT03502421)
- Testing
- Ketamine
- Sponsor
- University of South Florida
Chronic Physical Health Conditions
MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace
The specific aim of the study is to evaluate the health benefits of a series of group workshops designed for workers with chronic physical health conditions.
- Trial name
- NCT01978392
- Testing
- Self-management group workshops
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Chronic Pain
Treatment, Pain, and Opioids
Background: Chronic pain and negative consequences of long-term opioid therapy are related public health concerns associated with significant functional impairment, high psychiatric comorbidity, and premature mortality…
- Trial name
- NCT05363176
- Testing
- Cognitive-Behavioral Therapy for Treatment Seeking, Pain treatment education
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development