Clinical trials: Chronic Pain Patients
Chronic Pain, Covid19
Effects of COVID-19 in Chronic Pain
The aim of this study is to evaluate the effects of the COVID-19 pandemic on pain, stress, sleep and quality of life in patients with chronic musculoskeletal pain and the relationships between them.
- Trial name
- NCT04878900
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Chronic Pain
Efficacy of Genicular Nerve Radiofrequency
In patients with knee pain, local anesthetics and radiofrequency applications to superolateral, superomedial and inferomedial genicular nerves that innervate the knee joint are also preferred methods besides analgesic and…
- Trial name
- NCT04100707
- Testing
- Genicular block was applied
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Chronic Low Back Pain, Chronic Sciatica
A Zhineng Qigong Intervention for Patients With Chronic Low Back Pain and/or Leg Pain
The purpose of this study is to evaluate a Zhineng Qigong intervention for patients with chronic low back pain and/or leg pain, and to test feasibility aspects.
- Conditions
- Chronic Low Back Pain, Chronic Sciatica, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- NCT04520334
- Testing
- Zhineng Qigong intervention
- Where
- 9 sites in Sweden
- Volunteers
- 55 people
- Sponsor
- Lund University
Low Back Pain, Chronic Pain
Preparatory Lifestyle Program Before Functional Restoration for Chronic Low Back Pain
Chronic low back pain is a major public health issue worldwide, affecting hundreds of millions of people. Intensive multidisciplinary rehabilitation programs, such as the Functional Restoration Program (FRP), are effective in…
- Trial name
- PFRP-FRP (NCT07649707)
- Testing
- 12-week preparatory lifestyle-based physical activity program, 4-week intensive Functional Restoration Program
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University of Artois
Refractory Angina Pectoris
Extracorporeal Shockwave Therapy for the Treatment of Refractory Chronic Angina Pectoris
Low intensity shockwaves have been proven in animal studies to induce local growth of new blood vessels from existing ones. The hypothesis of this study is that shockwave therapy could improve the symptoms of patients with…
- Trial name
- NCT01567644
- Testing
- Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Medispec
Chronic Interstitial Cystitis
The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)
This study is to evaluate the efficacy of urine biomarker in patients with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT02331472
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Back Pain
Influence of Verbal Suggestion on the Therapeutic Effect of the Joint Manipulation
The aim of the study is to evaluate the influence of verbal suggestion on the therapeutic effect of the joint manipulation of the lumbar spine in patients with chronic non-specific low back pain in relation to the pain level…
- Trial name
- NCT06537739
- Testing
- Lumbar manipulation, Negative communication - nocebo, Neutral communication
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- John Paul II University in Biała Podlaska
Postoperative Delirium, Chronic Postsurgical Pain
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
Single-celled sequencing for evaluating differences in gene expression patterns in different cell types of the dynamics of a means of this research as a starting point, to study the postoperative delirium and chronic pain at the…
- Trial name
- NCT05572307
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Back Pain, Chronic Pain
Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts
This study will demonstrate that functional improvement measures over a 6-month period for chronic low back patients under the care of Primary Care Provider (PCP), using a therapeutic plan formulated initially by the Pain…
- Conditions
- Back Pain, Chronic Pain, Pain, Intractable
- Trial name
- NCT02484937
- Testing
- Group 2 (PCP Treatment), Group 1 (PMS Treatment)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Sleep Disordered Breathing, Chronic Pain
Sleep Health Program for Patients With Chronic Pain
This is a pilot, prospective, randomized controlled trial of a novel sleep health program versus no sleep intervention in chronic pain patients.
- Conditions
- Sleep Disordered Breathing, Chronic Pain, Sleep
- Trial name
- NCT04299100
- Testing
- Sleep Health Program for Participants with No/Mild Sleep Apnea, Sleep Health Program for Participants with Moderate/Severe Sleep Apnea
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Moderate-to-severe Chronic Low Back Pain
Efficacy and Safety of Egalet-002 in Patients With Moderate-to-Severe Chronic Low Back Pain
The purpose of this study is to determine the analgesic efficacy of Egalet-002 twice daily (BID) in patients with moderate-to-severe chronic low back pain
- Trial name
- NCT02716857
- Testing
- Oxycodone extended-release
- Where
- 74 sites in United States
- Volunteers
- 549 people
- Sponsor
- Egalet Ltd
Chronic Calcific Pancreatitis
Intraoperative Coeliac Plexus Alcohol Neurolysis Along With Frey's Procedure for a Better Pain Relief
To study the effect of Intra operative Coeliac plexus alcohol neurolysis combined with Frey's procedure for effective pain relief in patients with Chronic Calcific Pancreatitis in a single centre setting with a Randomized…
- Trial name
- INFARCT (NCT02735330)
- Testing
- celiac plexus neurolysis using absolute alcohol, Frey's procedure
- Volunteers
- 136 people
- Sponsor
- Madras Medical College
Chronic Pain
Peculiarities of Pain in Patients With Gunshot Wounds Depending on the Localization of the Wound at the Stages of Treatment
Chronic pain, in turn, is associated with a whole cohort of mutually aggravating factors - this can lead to the development of extremely serious long-term consequences.
- Trial name
- PPPGWDL (NCT05489029)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 1,555 people
- Sponsor
- Bogomolets National Medical University
Pain
The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
Multimodal analgesia may be important for optimal postoperative pain treatment and facilitation of early mobilization and recovery.
- Trial name
- NCT01168531
- Testing
- Pregabalin, dexamethasone
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Lumbosacral Radicular Syndrome
PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management
The purpose of the study is to evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic lumbosacral radicular syndrome (LRS).
- Trial name
- NCT00991237
- Testing
- Pulsed Radiofrequency
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Postoperative Pain, Chronic Pain
The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients
Patients with a daily use of opioids may develop higher postoperative pain levels, often need high doses of morphine and therefore their pain may be difficult to treat.
- Conditions
- Postoperative Pain, Chronic Pain, Analgesics
- Trial name
- NCT02085577
- Testing
- (S)-(+)-Ketamine Hydrochloride Solution 25 mg/ml, Isotonic sodium chloride 0.9 percent, Paracetamol 1 g
- Where
- Denmark
- Volunteers
- 147 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Cervical Radicular Pain
Electrophysiological Predictors of Cervical DRG Pulsed Radiofrequency Outcomes
This observational study aims to determine whether electromyography and nerve conduction study findings can help predict the response to cervical dorsal root ganglion pulsed radiofrequency treatment in patients with chronic…
- Trial name
- NCT07776431
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Low Back Pain
A Single Ascending Dose Study of Safety and Tolerability of STA363 Compared to Placebo in 15 Patients With Chronic Discogenic Low Back Pain
A phase I, randomized, double-blinded, placebo-controlled, single ascending dose study to investigate the safety, local tolerability and transformation of nucleus pulposus following intradiscal injection of STA363 or placebo in…
- Trial name
- NCT03055845
- Testing
- STA363
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Stayble Therapeutics
Chronic Low-back Pain
COgNitive FuncTional Therapy+ for Chronic Low Back paIn
This study is a patient-blinded 2-arm randomized controlled trial (RCT) assessing the effectiveness (in the short and long term) as well as total healthcare costs of a CFT+ (a combined physiotherapist/psychologist intervention)…
- Trial name
- CONFeTTI (NCT04399772)
- Testing
- Cognitive Functional Therapy+ pathway, Interdisciplinary pain management pathway
- Where
- Denmark
- Volunteers
- 133 people
- Sponsor
- Odense University Hospital
Hysterectomy, Chronic Pain
Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy
Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete…
- Conditions
- Hysterectomy, Chronic Pain, Central Sensitisation, Anxiety Depression
- Trial name
- EPOCH (NCT04014829)
- Testing
- Pain-Pressure Threshold, Mechanical Temporal Summation, Hospital Anxiety and Depression Scale
- Where
- Singapore
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital