Clinical trials: Chronic Pain Syndrome
Migraine Disorders, Facial Pain Disorder, Cluster Headache, Trigeminal Neuralgia, Trigeminal Autonomic Cephalalgias
Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes
Purpose of the Study: This study aims to evaluate the clinical effectiveness and long-term outcomes of "Sphenopalatine Ganglion (SPG) Pulsed Radiofrequency (PRF)" treatment in patients with chronic headaches and facial pain.
- Trial name
- SPG-PRF (NCT07370142)
- Testing
- Pulsed Radiofrequency of the Sphenopalatine Ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
Fibromyalgia Syndrome
Effect of Soundscapes on Emotional Distress in Fibromyalgia: a 4×4 Crossover Trial
This study tests whether different types of sounds can help reduce emotional distress in people with fibromyalgia. Fibromyalgia is a condition that causes widespread muscle and joint pain and makes people extra sensitive to…
- Trial name
- FMSounDistress (NCT07231289)
- Testing
- Natural soundscape exposure, Urban soundscape exposure, Broadband sound active control
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Universidad de Granada
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071962
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Cystitis, Interstitial, Painful Bladder Syndrome
- Trial name
- NCT04275297
- Testing
- Psychosocial Treatment, Attention Control
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Vanderbilt University Medical Center
Scapulocostal Syndrome
Comparative Effects of Muscle Energy Technique and Modified Active Release Technique in Scapulocostal Syndrome.
The study was conducted to determine the comparative effects of Muscle Energy Technique and Modified Active Release Technique on Pain, Chest expansion and Functional disability in patients with Scapulocostal Syndrome.
- Trial name
- NCT07403227
- Testing
- Muscle Energy Technique, Modified Active Release Technique, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Chronic Pancreatitis, Pain Syndrome
Personalized Education and Pain Response in Chronic Pancreatitis
Pain mechanisms in chronic pancreatitis (CP) are heterogeneous and includes nociception, pancreatic neuropathy and central neuropathy/neuroplasty.
- Conditions
- Chronic Pancreatitis, Pain Syndrome, Depression, Anxiety
- Trial name
- PEPCP (NCT04654377)
- Testing
- Personalised education
- Where
- India
- Volunteers
- 114 people
- Sponsor
- Asian Institute of Gastroenterology, India
Hypermobile Ehlers-Danlos Syndrome, Pain Assessment
Oxytocin for Hypermobile Ehlers-Danlos Syndrome
The purpose of this pilot study is to evaluate effect of IV oxytocin on chronic pain in patients with Hypermobile Ehlers Danlos syndrome.
- Trial name
- EDS-OXY (NCT05405257)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Baylor College of Medicine
Complex Regional Pain Syndromes, Chronic Pain
Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up
Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features.
- Trial name
- TORNADO (NCT04597866)
- Testing
- Multimodal rehabilitation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
The Effectiveness of Temporomandibular Joint Mobilization and Exercise in Individuals With Chronic Neck Pain
To examine the effects of temporomandibular joint mobilization and exercises added to the conventional physiotherapy program on posture, functionality and muscular endurance in individuals with chronic neck pain.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Neck Pain, Chronic Pain
- Trial name
- NCT06005922
- Testing
- physiotherapy, TMJ exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Uskudar University
Tendinopathy
Shock Wave Therapy for Sural Myofascial Pain Associated to Chronic Heel Pain
The aim of this randomized controlled study in to investigate if a shock wave treatment extended to the gastrocnemius-soleus trigger points (TrP) is more effective than a standard treatment exclusively targeted at the plantar…
- Trial name
- NCT04385329
- Testing
- Shock wave therapy on plantar fascia extended to the gastrocnemius-soleus trigger points, Shock wave therapy on plantar fascia only
- Volunteers
- 55 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Fibromyalgia
FIbromyalgia anD GenetIcs Subgroups (FIDGIS)
Fibromyalgia syndrome (FS) is characterized by widespread pain and affect 0.5 to 5 % of the general population, with a higher prevalence in women.
- Trial name
- FIDGIS (NCT04624581)
- Testing
- Electrophysiological measurement of reflex nociceptive flexion threshold (RIII reflex) using Nicolet Vicking device
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Post COVID Condition, Chronic Pain
Effect of Non-Invasive Neuromodulation on Primary Chronic Pain, Including Post-COVID-19
The aim of this study is to analyse whether there is an advantage in adding low-intensity electrical stimulations to the vagus nerve with electrodes in the outer ear to control pain and fatigue in people with primary chronic…
- Conditions
- Post COVID Condition, Chronic Pain, Healthy
- Trial name
- NCT06689345
- Testing
- taVNS - transauricular vagal nerve stimulation, rPMS - repetitive peripheric magnetic stimulation, rTMS - repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Federal University of ABC
Fibromyalgia, Irritable Bowel Syndrome
Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders
Objectives : To investigate the analgesic effects of repeated sessions of unilateral rTMS in patients with chronic pain syndrome due to fibromyalgia, IBS or burning mouth syndrome. Primary outcome will be numerical pain scores.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Burning Mouth Syndrome
- Trial name
- NCT00374673
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
Chronic Pain
Physical Exercise, Motor Activity and Post-mastectomy Pain Syndrome.
Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.
- Trial name
- NCT05713786
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Coronary Disease, Acute Coronary Syndrome
European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease (EUROASPIRE VI)
The goal of this observational study is to provide a unique European picture of preventive action by cardiologists, other specialists and primary care physicians looking after patients with coronary heart disease (CHD)…
- Conditions
- Coronary Disease, Acute Coronary Syndrome, Unstable Angina, ST Elevation Myocardial Infarction
- Trial name
- EUROASPIRE VI (NCT06495177)
- Where
- Turkey (Türkiye)
- Volunteers
- 8,000 people
- Sponsor
- European Society of Cardiology
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Chronic Pelvic Pain Syndrome
Combined Sono-electro-magnetic Therapy for Treatment of Refractory Chronic Pelvic Pain Syndrome
Treatment of chronic pelvic pain syndrome (CPPS) is challenging for patients and physicians once conventional therapies fail. We hypothesize that combined sono-electro-magnetic therapy can improve refractory CPPS in men.
- Trial name
- NCT00688506
- Testing
- combined sono-electro-magnetic therapy (Sonodyn Medico Star)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Low Back Pain (Non-specific, Uncomplicated)
Evaluation of the Effectiveness and Safety of Mesotherapy in the Treatment of Chronic Low Back Pain Syndrome
The aim of this study is to evaluate the effectiveness of collagen mesotherapy in the treatment of chronic low back pain (CLBP) in the lumbosacral spine.
- Trial name
- NCT07675304
- Testing
- Tropocollagen type I, Lignocaine 1% concentration solution
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Chronic Low-back Pain
The Effectiveness of Kinesio Taping in Patients With Chronic Low Back Pain
The objective of this study is to determine the effectiveness of Kinesio taping (KT) with Conventional Physical therapy (CPT) - Transcutaneous Electrical Nerve Stimulation (TENS) and Supervised Exercise therapy and CPT in the…
- Trial name
- NCT05173948
- Testing
- Kinesio taping, Conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- University of Tabuk