Clinical trials: Chronic Periodontitis
Chronic Periodontitis
Relationship Between Chronic Periodontitis and Vitamin D and Calcium in Men
Objective: The objective was to evaluate whether serum vitamin D and calcium concentrations are associated with chronic periodontitis in Syrian men Methods: This study designed as "Matched Case-Control Study".200 males will be…
- Trial name
- NCT02127346
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Damascus University
Periodontitis, Adult, Periodontitis, Aggressive
Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis
The first step in the management of periodontal disease involves the non-surgical removal of the soft and hard bacterial deposits at all supra- and sub-gingival sites, especially into deep pockets, which can be carried on with…
- Trial name
- GBT2017 (NCT04264624)
- Testing
- Perioflow and Erythritol powder and ultrasonic debridement, Airflow and Erythritol powder and ultrasonic debridement
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Chronic Periodontitis
Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care
Chronic periodontitis is a common infectious disease characterized by progressive attachment loss and alveolar bone resorption eventually resulting in tooth loss.
- Trial name
- Listerine (NCT01195493)
- Testing
- Essential Oils solution, negative control solution
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Necrotic Pulp
Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis
Earlier, it was believed that successful regeneration cannot be achieved once tooth has become infected. However, recent studies suggest that regenerative endodontics may in fact be possible in teeth with pulpal necrosis and…
- Trial name
- NCT04606719
- Testing
- Advanced Platelet Rich fibrin
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis
CBD Effects on Periodontal Health of Patients With Chronic Periodontitis
The suppression of chronic periodontitis after application of dental gel and toothpaste containing cannabidiol (CBD) will be evaluated.
- Trial name
- Stoma-CBD (NCT05498012)
- Testing
- Cannabidiol dental gel, Cannabidiol toothpaste
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- Palacky University
Periodontal Diseases, Chronic Periodontitis
Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome
The purpose of this study was to demonstrate in patients with generalized chronic periodontitis that switching from cigarette smoking to using IQOS improves the response to periodontal therapy and the overall oral health status…
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Pocket, Tooth Mobility
- Trial name
- NCT03364751
- Testing
- IQOS, Cigarette
- Where
- 26 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Philip Morris Products S.A.
Periapical Periodontitis
The Importance of Prostaglandin and Nitric Oxide Synthesis in Apical Periodontitis
A total of 185 subjects were divided into three categories: AP group (n=85), CP group (n=50) and healthy control group (n=50). The AP group was divided into 3 subgroups according to abscess scoring (AS-PAI) based on the…
- Trial name
- NCT06023901
- Testing
- Apical periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Periodontitis, Type2 Diabetes
Serum Ferritin and Hepicidin Concentration in Chronic Periodontitis Patients With T2DM
serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease
- Trial name
- NCT03964428
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University
Periodontitis
L-PRF Plus Non Surgical Periodontal Treatment
Abstract: Background: Leucocyte and Platelet-Rich Fibrin (L-PRF) has shown to promote regenerative processes, even reporting antibacterial effect.
- Trial name
- NCT04520438
- Testing
- Leukocyte and platelet rich fibrin, Non-Surgical Periodontal treatment
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Periodontis, Aggressive Periodontitis
Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
The goal of this observational study is to investigate cellular heterogeneity and inflammatory microenvironment features in gingival tissues from patients with aggressive periodontitis compared to chronic periodontitis and…
- Trial name
- NCT07487272
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Periodontitis
Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.
Periodontal disease is an infectious disease resulting in inflammation within supporting tissues of the teeth, progressive attachment loss, and bone loss.
- Trial name
- NCT02121665
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 42 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Oxidative Stress, Chronic Apical Periodontitis
Effect of Different Root Canal Sealers on Oxidative Stress Markers
The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session.
- Trial name
- NCT07059481
- Testing
- Root Canal Treatment and Sample Collection, PAI Score Comparasion
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- bengi gülgü
Periodontitis, Laser
Clinical Evaluation of the Effect of LANAP as an Adjunct Treatment in Management of Patients With Chronic Periodontitis
this study evaluate the effect of LANAP (Laser Assisted New Attachment Procedure) as an Adjunct Treatment in Management of Patients With Chronic Periodontitis and assay the effect of LANAP on periodontal indexes like BOP, CAL…
- Trial name
- NCT03365167
- Testing
- LANAP (Laser Assisted New Attachment Procedure), LANAP off
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Apical Periodontitis, Healhty
Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis
Inflammation is a common factor in chronic periodontitis and systemic diseases. However, to date, there is no scientific evidence supporting a causal effect of inflammation caused by apical periodontitis on endothelial barrier…
- Trial name
- NCT07292363
- Testing
- Apical lesions cure
- Where
- 2 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Periodontitis
Effect Of Non-Surgical Periodontal Treatment On Lipoxin a4 Levels
The aim of this study was to evaluate the levels of lipoxin A4 (LXA4), prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in gingival crevicular fluid (GCF) and saliva in individuals with periodontal healthy and chronic…
- Trial name
- NCT04053660
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ordu University
Menopausal Patients, Chronic Periodontitis
Treatment of Periodontitis in Menopausal Patients
The goal of this clinical trial is to compare the effectiveness of polyunsaturated fatty acids (PUFAs) [omega-3] as an adjunctive treatment to scaling and root planing for menopausal women with periodontitis versus scaling and…
- Conditions
- Menopausal Patients, Chronic Periodontitis, Omega 3 Fatty Acids
- Trial name
- NCT06254118
- Testing
- Polyunsaturated Fatty Acids, olive oil
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Hadir F. El-Dessouky
Chronic Periodontitis, Depression
Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis
This study will evaluate whether use of antidepressants can reduce gingival inflammation in patients with periodontal (gum) disease.
- Trial name
- NCT03553095
- Testing
- Periodontal Surgery
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Inflammation
The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups
the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients
- Trial name
- NCT06140394
- Testing
- diode laser, non surgical scaling
- Where
- 2 sites in Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Chronic Periodontitis, Aggressive Periodontitis
Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System
In the present clinical study including chronic, aggressive periodontitis and healthy individuals, the investigators aimed to determine the RANKL, osteoprotegrin (OPG), Interleukin-1 (IL-1β), IL-10, IL-1β levels in gingival…
- Conditions
- Chronic Periodontitis, Aggressive Periodontitis, RANKL/OPG Ratio, Gingival Crevicular Fluid
- Trial name
- NCT02190773
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Periodontitis, Occlusal Trauma
Alterations in Subgingival Microbiota and Hypoxia in Occlusal Trauma
Present study suggests that excessive occlusal forces did not cause a significant change in hypoxia and vascular markers, however a slight alteration in subgingival microbiota was observed.
- Trial name
- NCT03621891
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University