Clinical trials: Chronic Post-operative Pain
Chronic Postoperative Pain
Data Collection for Prediction of Postoperative Chronic Pain for a Software
Postoperative Persistent Pain (PPP) is reported with a high incidence in adults 11.5-47%. This high incidence effects quality of life of patients causes social-economical problems and arises medico-legal issues.
- Trial name
- NCT02190682
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 733 people
- Sponsor
- Istanbul University
Total Knee Replacement, Post-operative Pain
Tapentadol vs Tramadol in Total Knee Arthroplasty
Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).
- Conditions
- Total Knee Replacement, Post-operative Pain, Chronic Pain
- Trial name
- NCT06269770
- Testing
- Tapentadol, Tramadol
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Thessaly
Chronic Pain, Post-operative Pain
Minocycline to Reduce Pain After Carpal Tunnel Release
The investigators are looking at whether peri-operative minocycline will reduce the duration of pain after minor hand surgery: carpal tunnel release and trigger finger release.
- Trial name
- NCT02051296
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Postoperative Pain
Effect of Intercostal Nerve Block With Ropivacaine Combined With Mecobalamine on Chronic Pain After Thoracic Surgery
This project intends to investigate the effects of intercostal nerve block with ropivacaine combined with mecobalamin on chronic post-surgical pain (CPSP) in thoracic postoperative patients.
- Trial name
- NCT04217213
- Testing
- Intercostal nerve block
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Xuzhou Medical University
Pain
Selective Neurectomy and Mesh Removal for Chronic Postherniotomy Pain
Chronic postherniotomy pain affects every day activities in 5-8% of patients. However, no established treatment for this pain syndrome exists and previous reports on the effect of surgical intervention suffer from methodological…
- Trial name
- NCT00627289
- Where
- 2 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-Surgical Pain, Chronic, Post-traumatic Pain, Chronic
Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation
This research aims to uncover the Mechanisms of pain relief through the FDA-cleared peripheral transcutaneous magnetic stimulation (pTMS) device by MagVenture.
- Trial name
- NCT07199361
- Testing
- Peripheral Transcutaneous Magnetic Stimulation from MagVenture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida International University
Chronic Pain, Acute Pain
Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs
The aim of this study is to evaluate the impact of intravenous lidocaine on acute and chronic post surgical pain on patients undergoing video assisted thoracoscopic surgery(VATS).
- Conditions
- Chronic Pain, Acute Pain, Neuralgia
- Trial name
- NCT02862769
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postsurgical Pain, Abdominal Pain
The Analgesic Efficacy of Δ9-THC (Namisol®) in Patients With Persistent Postsurgical Abdominal Pain
Persistent postsurgical abdominal pain (PPAP) is a very difficult to treat pain. This pain can persist for months or even years and significantly diminishes quality of life.
- Conditions
- Postsurgical Pain, Abdominal Pain, Chronic Pain
- Trial name
- NCT01562483
- Testing
- Tetrahydrocannabinol
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Radboud University Medical Center
Chronic Pain
Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
The purpose of this study is to learn whether or not certain risk factors and patient characteristics are linked with and possibly can predict the development of chronic pain after lumbar spine surgery.
- Trial name
- NCT03444168
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Postoperative Pain, Chronic Pain
The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients
Patients with a daily use of opioids may develop higher postoperative pain levels, often need high doses of morphine and therefore their pain may be difficult to treat.
- Conditions
- Postoperative Pain, Chronic Pain, Analgesics
- Trial name
- NCT02085577
- Testing
- (S)-(+)-Ketamine Hydrochloride Solution 25 mg/ml, Isotonic sodium chloride 0.9 percent, Paracetamol 1 g
- Where
- Denmark
- Volunteers
- 147 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Inguinal Hernia, Postoperative Pain
Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal hernia repair is one of the most frequently performed operations in young men. Persistent pain after inguinal surgery represents a significant cause of disability, occurring in between 15%-35% of cases.
- Trial name
- NCT00825344
- Testing
- Etanercept, Saline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Pain, Chronic, Pain, Postoperative
Evaluation of Dermatomal Distribution in the Erector Spinae Plane (ESP) Block
Interventional study that evaluate dermatomal distribution and its demographic determinants in patients who underwent to Erector Spinae Plane (ESP) block
- Trial name
- NCT03831581
- Testing
- Erector Spinae Plane Block
- Where
- Colombia
- Volunteers
- 16 people
- Sponsor
- Universidad de Antioquia
Chronic Postoperative Pain
Dexmedetomidine for Prevention of Chronic Postoperative Pain
Chronic postoperative pain (CPSP) is common symptom in patients after surgery, seriously affected the quality of life. Accumulating evidences have demonstrated dexmedetomidine can improve chronic pain.
- Trial name
- NCT03275207
- Testing
- saline, dexmedetomidine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhongda Hospital
Phantom Limb Pain
Virtual Mirror Therapy for Relief of Chronic Phantom Limb Pain
The purpose of this project is to further investigate the use of Virtual Mirror therapy for alleviating symptoms of chronic phantom limb pain.
- Trial name
- NCT05194800
- Testing
- Virtual Mirror Therapy
- Sponsor
- University of Alabama at Birmingham
Postoperative Pain, Opioid Use
SPSIP Block Versus ESP Block for Chronic Pain After Unilateral Breast Surgery
This prospective, randomized, assessor-blinded study will compare serratus posterior superior intercostal plane block and erector spinae plane block in adult female patients undergoing unilateral breast surgery.
- Trial name
- SPES-CPSP (NCT07674836)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Ultrasound-guided Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Engin Çetin
Failed Back Surgery Syndrome, Limb Ischemia
Evaluation of Online Tool (E-TOOL SCS) in Spinal Cord Stimulaion
This observational multicenter study aims to evaluate the reliability and validity of the e-tool for selecting patients eligible for SCS for chronic pain caused by one of the four etiologies listed above in the experience of…
- Conditions
- Failed Back Surgery Syndrome, Limb Ischemia, Neuropathic Pain, Complex Regional Pain Syndromes
- Trial name
- E-TOOLSCS (NCT06229015)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Post Operative Pain
Combined Supraclavicular Block and General Anesthesia in Pediatric Patients With Chronic Kidney Disease
compare the safety and efficacy of ultrasound-guided supraclavicular block in addition to general anesthesia in pediatric patients undergoing upper limb superficialization of arteriovenous fistula for hemodialysis.
- Trial name
- NCT05580094
- Testing
- general anesthesia only., general anesthesia plus supraclavicular block.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Acute Postoperative Pain
Effects of tDCS and VNS on Postoperative Analgesia
This study seeks to evaluate the efficacy of transcranial direct current stimulation (tDCS) and Afferent Vagus nerve simulation (VNS) in treating acute postoperative pain of patients in the post-anesthesia care unit after general…
- Trial name
- NCT06554067
- Testing
- Active transcranial direct current stimulation, Active vagus nerve stimulation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Columbia University
Chronic Pain, Other Functional Disturbances Following Cardiac Surgery
Functional and Anatomical MRI of the Spinal Cord and Peri-spinal Tissues
The current study is an amendment to a previously approved blinded randomized controlled trial (NCT02697812) which examines the rate at which the sternal retraction maneuver is performed during cardiac surgery (standard over 30…
- Trial name
- NCT02925364
- Testing
- magnetic resonance imaging (MRI)
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Dr. Tarit Saha