Clinical trials: Chronic Post-operative Pain
Chronic Post-cesarean Pain
Evaluation of the Incidence of Chronic Post-cesarean Pain as Part of an Enhanced Recovery After Surgery (ERAS) Protocol.
Enhanced Rehabilitation After Surgery (ERAS), developed in the 1990s, is a program encompassing a set of measures before, during and after surgery aimed at improving management by promoting the early recovery of the patient's…
- Trial name
- ChroCéRAAC (NCT04919408)
- Testing
- telephone survey
- Where
- 2 sites in France
- Volunteers
- 283 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Acute Pain, Postoperative, Chronic Pain
Effect of Rebound Pain on Chronic Postsurgical Pain After Total Knee Arthroplasty
This prospective observational study aims to evaluate whether rebound pain after peripheral nerve block is associated with the development of chronic postsurgical pain following elective total knee arthroplasty.
- Conditions
- Acute Pain, Postoperative, Chronic Pain, Arthroplasty, Replacement, Knee
- Trial name
- NCT07511985
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Konya City Hospital
Postoperative Pain, Chronic Pain
A Clinical Trial of a Psycho-educational Intervention to Improve Pain Management After Day Surgery
Evidence indicates that postoperative pain after day surgery is inadequately controlled. Patients have different experiences and knowledge about how to deal with pain, and the need for information and clarification may vary.
- Trial name
- NCT01595035
- Testing
- psychoeducational
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo Metropolitan University
Pain, Chronic Post-Surgical
PERIoperative Holistic RIsk Factor SCreening in the Prevention of Persistent Pain
Assessment and management for improved wellbeing after elective surgery (PERISCOP³E-Care) Diagnostic assessment tool evaluation and cut-off determination for participation in a transmural perioperative care program
- Trial name
- PERISCOPEcare (NCT05526976)
- Testing
- PERISCOPE-care
- Where
- 2 sites in Belgium
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Post-Operative Pain, Chronic, Necrotic Pulp
Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide.
- Trial name
- NCT04983524
- Testing
- propolis, Calcium Hydroxide
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Intercostal Neuralgia
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain.
- Trial name
- NCT01314482
- Testing
- Minocycline
- Where
- Australia
- Volunteers
- 116 people
- Sponsor
- University of Adelaide
Postoperative Pain, Postherniotomy Pain
Neurophysiological Characterization of Postherniotomy Pain
Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome.
- Conditions
- Postoperative Pain, Postherniotomy Pain, Neuropathic Pain
- Trial name
- NCT00719368
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Inguinal Hernia, Adult
Comparison of Self Fixating Mesh to Mesh Fixation With Metallic Tacks in Laparoscopic Inguinal Hernia Repair
This study compares the use of self-fixating mesh to mesh fixation with tackers in the management of inguinal hernia by laparoscopic method.
- Trial name
- SELFITAC (NCT03564535)
- Testing
- Self fixating group, Tacker fixation group
- Where
- India
- Volunteers
- 112 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Social Support, Coping Behavior
Impact of Social Support and Coping Strategies on Post-Surgical Pain
The purpose of the study is to evaluate the impact of social support and pain coping strategies in the development and evolution of post-surgical pain.
- Conditions
- Social Support, Coping Behavior, Post-Surgical Pain, Chronic
- Trial name
- POPQUEST (NCT05009316)
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 368 people
- Sponsor
- Université Catholique de Louvain
Chronic Pain
Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
The goal of this research proposal is to determine if the intraoperative administrative of Ketamine and Magnesium during laparoscopic gynecologic surgery improves postoperative pain in patients on chronic opioid therapy for…
- Trial name
- NCT02940509
- Testing
- Ketamine plus Magnesium sulfate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Acute Post-operative Pain, Chronic Post Operative Pain
Duloxetine Impact on Postoperative Pain Control and Outcomes
1. Evaluate differences between patients taking Duloxetine or placebo following lateral lumbar interbody fusion for postoperative narcotic consumption. 2.
- Conditions
- Acute Post-operative Pain, Chronic Post Operative Pain, Narcotic Use, Opioid Use
- Trial name
- NCT05611749
- Testing
- Duloxetine 60 MG
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Pain, Acute, Pain, Chronic
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
This study is a single-center, phase II, randomized, placebo-controlled, Bayesian-designed, double-blinded trial Goal and Questions: The primary goal is to evaluate if a combination of taurine and butyrate can reduce chronic…
- Conditions
- Pain, Acute, Pain, Chronic, Chronic Post Operative Pain
- Trial name
- NCT07144033
- Testing
- Butyrate and Taurine
- Where
- Hong Kong
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Pain, Postoperative
Personalized Prediction of Persistent Postsurgical Pain
P5 is planned as a prospective observational study, collecting evidence-based perioperative data on patient history and demographics, physical function, cognitive measures, psychological, and biological markers associated with…
- Trial name
- P5 (NCT04864275)
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Washington University School of Medicine
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Exploring the effects of repeated transcranial magnetic stimulation (rTMS) during the perioperative period on the incidence of postoperative delirium, postoperative cognitive dysfunction, and chronic postoperative pain in elderly…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Chronic Post-surgical Pain
- Trial name
- NCT06392919
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Affiliated Hospital of Nantong University
Cesarean Section Complications, Cesarean Section
Persistent Pain After Cesarean Delivery - A Danish Multicenter Cohort Study
In Denmark, around 12,700 patients undergo Cesarean delivery (CD) annually, constituting approximately 20% of all childbirths in the country.
- Conditions
- Cesarean Section Complications, Cesarean Section, Cesarean Delivery, Persistent Pain
- Trial name
- NCT06247852
- Where
- Denmark
- Volunteers
- 477 people
- Sponsor
- Nordsjaellands Hospital
Postoperative Pain, Chronic Pain Post-Proceduraal
QLB and Laparoscopic Nephrectomy, Postoperative Pain and Recovery
There are ca 900 new cases of kidney cancer in Finland/year. The curative therapy for kidney cancer is partial or total nephrectomy depending on the localization and the size of tumor. Main of these operations are laparoscopic.
- Conditions
- Postoperative Pain, Chronic Pain Post-Proceduraal, Nausea and Vomiting, Postoperative
- Trial name
- NCT03339284
- Testing
- Dexamethasone sodium phosphate, Ropivacaine Hydrocloride, Sodium Chloride 9mg/mL
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Tampere University Hospital
Brain Tumor
Brain Tumor Surgery and Postoperative Delirium
1. To explore whether the combined administration of dexmedetomidine during and after surgery in patients undergoing brain tumor resection is an effective and safe modality to prevent postoperative delirium and improve sleep…
- Trial name
- NCT06863064
- Testing
- Dexmedetomidine, Normal Saline
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Chronic Apical Periodontitis
Evaluation of Post-Operative Pain Following the Use of Nano-Calcium Hydroxide
The goal of this clinical trial is to evaluate the effect of different intracanal medicaments-conventional calcium hydroxide (CH) and nano-sized calcium hydroxide (NCH)-on the intensity of postoperative pain following root canal…
- Trial name
- NCT07057336
- Testing
- Conventional Calcium Hydroxide (CH), Nanocalcium Hydroxide (NCH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cukurova University
Chronic Pain, Postoperative, Sternotomy Pain
Early Screening of Chronic Post-sternotomy Pain Using the DN4-i Questionnaire
Chronic post-sternotomy pain (CPSP) is a common complication after cardiac surgery, with a reported prevalence between 30% and 50%.
- Trial name
- DEPDN4i (NCT07603271)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institute Arnault Tzanck, France
Knee Arthroplasty, Total, Partial Knee Arthroplasty
Opioid Reduction and Enhanced Recovery in Orthopaedic Surgery (OREOS)-Knee
Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery.
- Conditions
- Knee Arthroplasty, Total, Partial Knee Arthroplasty, Chronic Pain, Postoperative, Osteoarthritis (OA) of the Knee
- Trial name
- OREOS-K (NCT07895472)
- Testing
- Standard care, Multicomponent opioid reduction and pain management pathway
- Volunteers
- 170 people
- Sponsor
- McMaster University