Clinical trials: Chronic Post-thoracotomy Pain
Neuropathic Pain, Thoracic Surgery, Video Assisted
Chronic Pain After Thoracotomy (Video Assisted Thoracic Surgery - VATS)
This is an explorative study investigating potential nerve injury after VATS.
- Conditions
- Neuropathic Pain, Thoracic Surgery, Video Assisted, Chronic Pain
- Trial name
- NCT01068457
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-operative Intercostal Neuralgia
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain.
- Trial name
- NCT01314482
- Testing
- Minocycline
- Where
- Australia
- Volunteers
- 116 people
- Sponsor
- University of Adelaide
Acute Pain, Chronic Pain
Acute and Chronic Pain, Especially Neuropathic Pain, After Thoracotomy and Continuous Application of Ketamine.
Chronic Pain, especially neuropathic pain, are adverse events after posterolateral thoracotomy for lung resection. The continuous application of ketamine may have a prophylactic effect and helps to prevent chronic pain.
- Conditions
- Acute Pain, Chronic Pain, Neuropathic Pain
- Trial name
- NCT03105765
- Testing
- Ketamine
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Chronic Pain
Pregabalin and Post-thoracotomy Pain
With Institutional Ethics Board approval and signed informed consent, a pilot investigation was conducted in which 15 adult patients scheduled to undergo a thoractomy were randomly assigned to receive 1) 150 mg pregabalin 1 hour…
- Trial name
- NCT00663962
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Queen's University
Thoracotomy, Chronic Pain
Chronic Pain After Thoracotomy, an Incidence Study in a Single Surgical Center
Investigation of chronic pain frequency after thoracotomy for lung cancer. Risk factors for development of chronic pain are investigated. Questionnaire survey.
- Trial name
- NCT00834769
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hopital Foch
Anesthesia, Thoracic Diseases
The Effectiveness of ThOracic Epidural and Paravertebral Blockade In Reducing Chronic Post- Thoracotomy Pain: 2
An estimated 7200 thoracotomies (surgical incision into the chest wall) are performed annually in the UK, most commonly to treat lung cancer.
- Trial name
- TOPIC-2 (NCT03677856)
- Testing
- Paravertebral blockade, Thoracic epidural block
- Where
- United Kingdom
- Volunteers
- 1,026 people
- Sponsor
- University of Birmingham
Chronic Postoperative Pain
Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention
This study will test the null hypothesis that low-dose ketamine given peri-operatively will have no effect on the development of chronic post-surgical pain, in patients undergoing thoracotomy or video assisted thoracic surgery…
- Trial name
- NCT01296347
- Testing
- Ketamine
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Imperial College Healthcare NHS Trust
Chronic Pain, Thoracic
Chronic Pain After Cardiothoracic Surgery
This is a prospective cohort study to estimate prevalence of chronic pain after cardiothoracic surgery
- Conditions
- Chronic Pain, Thoracic, Chronic Pain Syndrome
- Trial name
- NCT05702125
- Volunteers
- 96 people
- Sponsor
- Universitas Indonesia
Postoperative Pain, Chronic Pain
Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE).
To assess the effects of prolonged preoperative gabapentin treatment (10 days) on chronic pain after thoracotomy.
- Trial name
- GABATHOMIE (NCT03158376)
- Testing
- Gabapentin
- Where
- France
- Volunteers
- 201 people
- Sponsor
- University Hospital, Lille
Atrial Fibrillation, Neuropathic Pain
Atrial Fibrillation and Neuropathic Pain After Thoracotomy and Continuous Application of Magnesium Sulphate.
Atrial fibrillation and chronic neuropathic pain are adverse events occurring after posterolateral thoracotomy for lung resection. The continuous application of magnesium sulphate may have a prophylactic effect.
- Trial name
- NCT02008747
- Testing
- Magnesium sulphate
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Thoracotomy, Chronic Pain
Sensory Changes From Chest Drains
Does chest drains contribute to the post thoracotomy pain syndrome
- Trial name
- NCT01274871
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Postthoracotomy Pain, Chronic Postthoracotomy Pain
The Effect of Paravertebral Block Using a Multi-orifice Catheter on Preventing Acute and Chronic Post-thoracotomy Pain
This study aims to evaluate the effect of the paravertebral block using a multi-lumen catheter on the incidence and severity of acute and chronic postthoracotomy pain compared to the thoracic epidural block.
- Conditions
- Acute Postthoracotomy Pain, Chronic Postthoracotomy Pain, Hypotension After Bolus Dose
- Trial name
- NCT01039870
- Testing
- paravertebral block, thoracic epidural analgesia
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Lung Cancer
Evaluation of Chronic Pain After Nerve Section During Thoracotomy
The purpose of this study is to investigate if controlled nerve section reduces chronic pain after thoracotomy.
- Trial name
- NCT00653367
- Testing
- Nerve section
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Pain, Dexamethasone
Dexamethasone for Reduction of Post Thoracotomy Pain Syndrome
Post thoracotomy pain syndrome still affects 50% of patients after a thoracic surgery. Pathogenesis is unclear but there is growing evidence that neuro inflammation may play a significant role.
- Conditions
- Chronic Pain, Dexamethasone, Thoracic Surgery, Cytokines
- Trial name
- NCT02112864
- Testing
- Dexamethasone, Normal Saline
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Pain, Postoperative, Intrathoracic Procedure
Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy
The researchers will compare the common methods of post-surgical pain control, such as epidural or intercostal nerve block with a newer method called cryoablation.
- Trial name
- NCT06384664
- Testing
- Atricure's crysoSPHERE probe, Standard of Care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain
Intraoperative Cryoanalgesia for Extended Pain Management Following Thoracotomy
The ICE Study study will compare standard therapy (thoracic epidural) versus a novel approach (Cryoanalgesia combined with thoracic epidural) in subjects undergoing unilateral thoracotomy.
- Conditions
- Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain, Post-thoracotomy Pain Syndrome
- Trial name
- ICE (NCT03538340)
- Testing
- Thoracic Epidural, Intercostal Cryoanalgesia
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of Maryland, Baltimore
Lung Transplantation
Chronic Pain After Lung Transplantation, an Incidence Study
This is an investigation on the frequency of chronic pain amongst recipients after lung transplantation. Factors relating to the development of chronic pain are investigated.
- Trial name
- NCT00745654
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-thoracotomy Pain Syndrome
Erector Spinae Plane Block for Post-thoracotomy Pain Control
The thoracic epidural block (TEB) and thoracic paravertebral block (TPVB) are the most commonly used techniques for analgesia after thoracic surgery.Recently, erector spinae plane block (ESPB) was reported as a treatment for…
- Trial name
- NCT04531553
- Testing
- Thoracic epidural analgesia, ESPB with levobupivacaine and dexmedetomedine, ESPB with levobupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Neuropathic Pain, Thoracotomy
Sensory Perception After Thoracotomy
The study will investigate characteristics of chronic pain after thoracotomy
- Conditions
- Neuropathic Pain, Thoracotomy, Chronic Pain
- Trial name
- NCT00910949
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thoracic Neoplasm, Chronic Pain Post-Procedural
Preoperative Paravertebral Block in Cancer Surgery of the Lung
The investigators aim to determine whether ultrasound-guided preemptive paravertebral blockade (PVB) local anaesthetic (pre-PVB LA), administered in addition to the post-operative PVB (post-PVB) local anaesthetic (LA) infusion…
- Conditions
- Thoracic Neoplasm, Chronic Pain Post-Procedural, Acute Post-thoracotomy Pain, Anesthesia, Local
- Trial name
- ParaSOL (NCT04209868)
- Testing
- Levo-Bupivacaine Hydrochloride (HCl) 0.5 % in 20mL Injection, 0.9% Sodium Chloride 20mL Injection
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust