Clinical trials: Chronic Pulmonary Disease
Asthma
Clinical Assessment of Acupuncture for the Treatment of Chronic Asthma
The purpose of this study is to assess whether acupuncture is effective in the treatment of chronic asthma.
- Trial name
- NCT01931696
- Testing
- Verum acupuncture
- Where
- 12 sites in China
- Volunteers
- 200 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease, HIV
Longitudinal Evaluation of HIV-associated Lung Disease Phenotypes
The overall hypotheses of this proposal are that discrete phenotypes of HIV Chronic Obstructive Pulmonary disease (COPD) differ in their trajectories, biomarkers, and risk factors and that persistent viral infection including…
- Conditions
- Chronic Obstructive Pulmonary Disease, HIV, Emphysema
- Trial name
- LEAP (NCT02238327)
- Testing
- blood draw, questionnaires, Lung function testing
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Pittsburgh
Respiratory Disease, Asthma
Digital App for Telerehabilitation in Respiratory Diseases
The purpose of this study is to evaluate the feasibility and the mid-term effects of a pulmonary rehabilitation intervention, delivered by digital App, on quality of life of patients affected by respiratory diseases.
- Conditions
- Respiratory Disease, Asthma, Long COVID, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05572346
- Testing
- Home-based telerehabilitation program delivered through digital devices
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- MedicAir Healthcare S.r.l.
Hepatopulmonary Syndrome (HPS)
Analysis of Clinical Features of Chronic Liver Disease Complicated With Hepatopulmonary Syndrome
Hepatopulmonary syndrome (HPS) has unknown pathogenesis, limited treatment and poor prognosis. The onset of HPS is insidious and easy to be ignored.
- Trial name
- NCT05932927
- Testing
- Proteomic sequencing
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Sun Jie
Chronic Obstructive Pulmonary Disease
Metformin in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine the effect of a tablet medication, called metformin, in flare-ups (exacerbations) of chronic obstructive pulmonary disease.
- Trial name
- NCT01247870
- Testing
- Metformin
- Where
- 9 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- St George's, University of London
Chronic Obstructive Pulmonary Disease (COPD)
Investigation of the Acute Effects of Traditional and Functional IMT on Muscle Oxygenation in COPD
This study aims to compare the effects of functional and conventional inspiratory muscle training (IMT) on post-exercise muscle deoxygenation in individuals with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT07267923
- Testing
- Traditional inspiratory muscle training, Functional inspiratory muscle training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Saglik Bilimleri Universitesi
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Bioequivalence Study of Budesonide/Formoterol Inhalation Powder in Healthy Participants
The goal of this study is to learn if a new formulation of Budesonide/Formoterol Inhalation Powder (160μg/4.5μg), manufactured by Shanghai New Huanghe Pharmaceutical Co., Ltd., works the same as the already approved reference…
- Trial name
- BF-BE (NCT07804303)
- Testing
- Budesonide and Formoterol Fumarate Powder for Inhalation (II) (Test), Budesonide and Formoterol Fumarate Powder for Inhalation (II) (Reference)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Xin Huanghe Pharmaceutical Co., Ltd.
COPD
The Effects of Atorvastatin Treatment in COPD Patients
Rationale: Retrospective studies suggest that statins improve outcomes in COPD patients possibly as a result of an anti-inflammatory effect.
- Trial name
- NCT01748279
- Testing
- Atorvastatin, Formoterol, Lactose tablet
- Where
- Poland
- Volunteers
- 18 people
- Sponsor
- Medical University of Bialystok
Spinal Cord Injuries, Tetraplegia, Unspecified, Incomplete, Chronic
Improving Hand Recovery With Neuromodulation in Tetraplegia
This study will examine a form of non-invasive brain stimulation applied with intensive therapy of the arm and hand. The goal of the study is to determine if arm and hand function can be improved in people with incomplete…
- Trial name
- IGNITE (NCT03954496)
- Testing
- transcranial direct current stimulation, Intensive upper extremity motor training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Sara Shahid Salles
Lung Neoplasms, Pulmonary Disease, Chronic Obstructive
A Study of Smoking Cessation Patterns in Participants Undergoing Lung Surgery
The purpose of this study is to assess the current smoking status and smoking cessation attempts among smokers or recent smoking quitters during the perioperative period, to describe postoperative pulmonary complications (PPCs)…
- Trial name
- CHAMPION (NCT04313361)
- Testing
- No intervention
- Where
- 3 sites in China
- Volunteers
- 290 people
- Sponsor
- Johnson & Johnson (China) Investment Ltd.
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether there is a statistical association between changes in sputum serial levels of two cytokines, interleukin (IL)-17 and IL-6, during the treatment course of a severe acute…
- Trial name
- NCT00281242
- Testing
- blood draw
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Michigan
Bronchiolitis Obliterans Syndrome
A Retrospective Chart Review Study of Patients With CLAD-BOS Post Lung Transplantation
The Primary Objective of this study was to evaluate the FEV1 trajectory of patients diagnosed with CLAD-BOS. The Secondary Objectives of this study were: To describe demographics of patients diagnosed with CLAD-BOS To describe…
- Trial name
- NCT06503770
- Where
- 6 sites in United States, Belgium and 1 more
- Volunteers
- 284 people
- Sponsor
- Zambon SpA
Hypogonadism, Chronic Obstructive Pulmonary Disease
Efficacy and Safety of Fispemifene in the Treatment of Hypogonadal Men With Chronic Obstructive Pulmonary Disease That Are on Oral Glucocorticoid Therapy
The objective of the study is to assess and compare the preliminary efficacy, safety and tolerability of fispemifene 300 mg and placebo given once daily for 4 weeks in the treatment of hypogonadal men with chronic obstructive…
- Trial name
- NCT01061970
- Testing
- Fispemifene
- Volunteers
- 15 people
- Sponsor
- QuatRx Pharmaceuticals Company
Pulmonary Disease, Chronic Obstructive
Sustaining Training Effects Through Physical Activity
This randomized control trial will investigate whether the implementation of a telecoaching program, initiated during pulmonary rehabilitation, is able to increase and maintain physical activity and general benefits until six…
- Trial name
- STEP (NCT02702791)
- Testing
- Telecoaching, pulmonary rehabilitation
- Where
- Belgium
- Volunteers
- 73 people
- Sponsor
- KU Leuven
COPD Exacerbation, Chronic Obstructive Pulmonary Disease Exacerbation
Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation
Chronic obstructive pulmonary disease (COPD) is a common disorder that affects approximately 400,000 Danish citizens. About 3,000-3,500 Danes die yearly because of the disorder, and the costs associated with hospital admissions…
- Trial name
- O2flow-COPD (NCT04223050)
- Testing
- Oxygen gas
- Where
- 4 sites in Denmark
- Volunteers
- 23 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
COPD
Assessment of Severity and Prognosis in Elderly Patients With COPD and Complex Chronic Comorbidities
Cigarette smoking, the major risk factor for Chronic Obstructive Pulmonary Disease (COPD), causes systemic effects, such as systemic cellular and humoral inflammation, that could substantially contribute to the development of…
- Trial name
- NCT01893918
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Allogeneic Hematopoietic Cell Transplant Recipients
Prospective Phase II Study for Assessment of Regulatory Immune Cell Populations After Allogeneic HSCT
Allogeneic hematopoietic cell transplantation offers high cure rates for patients with hematological and oncological diseases. Graft-versus-host disease (attack of donor's white blood cells on patient's tissues) is a serious…
- Trial name
- NCT00587574
- Where
- 2 sites in Austria, Czechia
- Volunteers
- 150 people
- Sponsor
- Medical University of Vienna
Chronic Hepatitis C
High-dose Ribavirin in Treatment of Chronic Hepatitis C Genotype 1 or 4
Optimal ribavirin dosages are essential in achieving SVR (sustained virological response). Several studies have shown higher SVR rates in patients receiving higher doses of ribavirin.
- Trial name
- VIRID (NCT00662220)
- Testing
- ribavirin
- Where
- 27 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Foundation for Liver Research
Chronic Obstructive Pulmonary Disease
Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this interventional, randomized, double-blind, monocentric, cross-over study is to quantify the possible deleterious effect on the cardiac autonomic nervous system control of two long-acting anticholinergic…
- Trial name
- LAB-Card (NCT02872090)
- Testing
- Indacaterol, Glycopyrronium, Tiotropium
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Disease, Diabetes
Pragmatic Randomized Control Trial of Telehealth vs Standard Care in Follow-up of Patients With Chronic Conditions
The Norwegian health authorities has initiated a three-year trial of telehealth solutions as part of the treatment of patients with chronic illness in the period 2018-2021.
- Conditions
- Chronic Disease, Diabetes, Vascular Diseases, Chronic Lung Disease
- Trial name
- MAO (NCT04142710)
- Testing
- Telemedicine: tablet and possibly tools to perform measurements
- Where
- 9 sites in Norway
- Volunteers
- 732 people
- Sponsor
- University of Oslo
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