Clinical trials: Chronic Pulmonary Obstruction
Moderate to Severe Chronic Obstructive Pulmonary Disease
A Continuation Study of Tilrekimig in Adults With Moderate-to-Severe Long-Term Breathing Difficulty, Known by the Medical Term of Chronic Obstructive Pulmonary Disease (COPD) to Learn About This Medicine When Used for a Long Period of Time
A Continuation Study of Tilrekimig in Adults with Moderate-to-Severe Long-Term Breathing Difficulty, Known by the Medical Term of Chronic Obstructive Pulmonary Disease (COPD) to Learn About this Medicine when Used for a Long…
- Trial name
- NCT07839884
- Testing
- Tilrekimig
- Volunteers
- 1,360 people
- Sponsor
- Pfizer
Chronic Obstructive Pulmonary Disease
To Assess the Efficacy and Safety of PT010 Compared to PT009 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
This is a 12-week chronic-dosing study to assess the efficacy and safety of BGF MDI compared to BFF MDI in subjects with moderate to very severe COPD.
- Trial name
- NCT03081247
- Testing
- BGF 320/14.4/9.6 µg MDI, BFF 320/9.6 µg
- Sponsor
- Pearl Therapeutics, Inc.
Chronic Obstructive Pulmonary Disease
Influence of the VitaBreath on Exercise Tolerance in COPD
People with COPD have more air in their lungs than other people (this problem with high lung volumes is called "hyperinflation").
- Trial name
- NCT03068026
- Testing
- VitaBreath, Pursed Lip Breathing technique
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- North Tyneside General Hospital
Chronic Obstructive Pulmonary Disease
Use of MonitorMe in COPD
MonitorMe is a telephone device intended for the non-critical monitoring of vital signs in a domestic environment with the ability to automatically transmit data to a remote location via basic telephone connectivity.
- Trial name
- NCT04108143
- Testing
- MonitorMe
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Lincoln
CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ASTHMA
Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)
Patients with chronic obstructive pulmonary disease (COPD) experience breathing difficulties because the airways deep in their lungs become narrowed. COPD patients use inhaler drugs to provide relief from breathlessness.
- Conditions
- CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ASTHMA, HEALTHY SUBJECTS
- Trial name
- NCT01721291
- Testing
- SALBUTAMOL
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obstructive Chronic Bronchitis With Acute Exacerbation
Respiratory Therapy in COPD Exacerbations
The purpose of this study is to determine effectiveness, feasibility and safety/tolerance of Respiratory Therapy in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease.
- Trial name
- TRESEPOCAS (NCT02125747)
- Testing
- No Respiratory Therapy, Respiratory Therapy
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Parc de Salut Mar
Obesity, Chronic Obstructive Pulmonary Disease
Ventilator Settings and Comfort
No studies have been done to examine whether patients with obstructive lung disease and obesity are more comfortable on some ventilator settings than on others.
- Trial name
- NCT01131390
- Testing
- Ventilator setting changes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Bridgeport Hospital
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease
The aim of the present study was to evaluate if the analysis of NT-proBNP might be used as an initial step for the diagnosis of chronic heart failure in patients with COPD in primary health care, and to select patients for a…
- Trial name
- NT-proBNP (NCT01801722)
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Lund University
Chronic Obstructive Pulmonary Disease
Education-Based İntervention Program for Persons With Chronic Obstructive Pulmonary Disease (EBIPCOPD)
Obstructive Pulmonary Disease(COPD) treatment, leading to the role of nurses to become more and more important. An Education-Based Intervention Program(EBIP) consists of several steps that aim to achieve better health outcomes…
- Trial name
- NCT04260178
- Testing
- An Education-Based Intervention Program and handbook (EBIP, hospital and home), PFT, BMI, BDI, SCMP-G
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gönül GÖKÇAY
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Mometasone Furoate/Formoterol Combination Versus Formoterol and Mometasone Furoate Alone in COPD (Study P04229AM4)(COMPLETED)
This is a randomized, placebo-controlled, parallel-group, multi-site, double-blind study evaluating the efficacy of mometasone furoate/formoterol fumarate (MF/F) metered dose inhaler (MDI) 400/10 mcg twice daily (BID) and MF/F…
- Trial name
- NCT00383435
- Testing
- Mometasone furoate/formoterol (MF/F) combination, Mometasone furoate MDI (MF MDI), Formoterol MDI
- Volunteers
- 1,055 people
- Sponsor
- Organon and Co
Chronic Obstructive Pulmonary Disease, Healthy
Biosensor and Environmental Sensor Development Within the REMEDIA Project
The aim of this proof-of-concept study is to obtain data that will contribute to the development of sensor devices (biosensor and environmental sensor) for patients with lung diseases (e.g. COPD).
- Trial name
- NCT06035276
- Testing
- Exposure to clean air, Exposure to urban air
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Chronic Respiratory Diseases
Intestinal Microbiota in COPD and Asthma
The composition of the intestinal microbiota, the level of lipopolysaccharides, TMAO in the blood, and other parameters of patients with COPD (n=50), asthma (n=50) and the control (n=40) will be assessed as factors associated…
- Trial name
- MicrObAs (NCT04802317)
- Testing
- Identification of the composition of the intestinal microbiota
- Where
- Russia
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Chronic Obstructive Pulmonary Disease
Effect of Oral Feeding on Patients With Chronic Obstructive Pulmonary Disease
This is a prospective, randomized controlled clinical trail that involved patients with Chronic Obstructive Pulmonary Disease.The goal of this clinical trial is to compare the clinical effect of Oral Tubes vs Nasogastric Tubes in…
- Trial name
- NCT06505876
- Testing
- Basic treatment, Oral Tube Feeding, Nasogastric Tube Feeding
- Volunteers
- 80 people
- Sponsor
- Chao Phya Abhaibhubejhr Hospital
Chronic Obstructive Pulmonary Disease
Identifying Inflammatory Biomarkers of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a condition that is characterized by airway obstruction due to inflammation. Levels of inflammatory proteins may be linked to when and to what extent COPD develops.
- Trial name
- NCT00394940
- Where
- United States
- Volunteers
- 2,085 people
- Sponsor
- University of Arizona
COPD (Chronic Obstructive Pulmonary Disease)
Respiratory Rehabilitation and Sleep Quality in COPD Patients
COPD affects 5 to 8% of the population in France. The disease consists of inflammation of the large and small airways causing permanent obstruction of the airways and symptoms such as dyspnea, cough and sputum that worsens over…
- Trial name
- REARSOM/BPCO (NCT06677268)
- Testing
- Rehabilitation
- Where
- 4 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Rouen
Pulmonary Disease, Chronic Obstructive
A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to Inhale
To demonstrate the efficacy of inhaled tiotropium + olodaterol via Respimat® on lung function in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD) with optimal and sub-optimal Peak Inspiratory Flow…
- Trial name
- NCT04223843
- Testing
- Tiotropium + olodaterol
- Where
- 26 sites in United States, Germany
- Volunteers
- 213 people
- Sponsor
- Boehringer Ingelheim
Lung Diseases, Obstructive, Bronchitis
Medication Adherence in COPD--A Self-Regulation Study
To test the effectiveness of a self-management program for chronic obstructive disease (COPD) patients. The program to improve adherence could be conducted by nurses or other clinic staff in settings where comprehensive…
- Conditions
- Lung Diseases, Obstructive, Bronchitis, Emphysema, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005717
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
COPD
A Safety, Tolerability and Efficacy Study in Chronic Obstructive Pulmonary Disease (COPD) Patients With QBM076.
This was a 2 Part study. Part 1 was a safety and tolerability study in GOLD I-III COPD patients. Part 2 was an efficacy study in GOLD I-III COPD patients.
- Trial name
- NCT01972776
- Testing
- QBM076
- Where
- 7 sites in United States, Germany and 2 more
- Volunteers
- 48 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Treatment of Chronic Obstructive Pulmonary Disease (COPD) With Diffusion Capacity Defect by REGEND001 Cell Therapy
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide with the characterization of obstructed airflow.
- Trial name
- NCT05638776
- Testing
- REGEND001 cell therapy
- Where
- 8 sites in China
- Volunteers
- 58 people
- Sponsor
- Regend Therapeutics
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.