Clinical trials: Chronic Pulmonary Obstruction
COPD, Emphysema
Anti-Platelets in Chronic Obstructive Pulmonary Disease
This is a 6 week crossover study in current and former smokers with and without COPD to evaluate whether 2 weeks of dual antiplatelet therapy (aspirin 81mg and clopidogrel 75mg) improves pulmonary perfusion (i.e.
- Conditions
- COPD, Emphysema, Emphysema or COPD
- Trial name
- NCT05567562
- Testing
- dual anti-platelet therapy
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training and COPD
Subjects with chronic obstructive pulmonary disease (COPD) frequently develop considerable deterioration in exercise capacity in association with weakness and deconditioning of the respiratory muscles, which can be corrected with…
- Trial name
- NCT04415788
- Testing
- Test of Incremental Respiratory Endurance - IMT, Threshold - IMT
- Where
- Czechia
- Volunteers
- 48 people
- Sponsor
- Brno University Hospital
Chronic Obstructive Pulmonary Disease
Supine Daoyin in the Treatment of AECOPD
The purpose of this study was to evaluate the clinical efficacy and safety of supine daoyin in the treatment of AECOPD.
- Trial name
- NCT04913961
- Testing
- Supine Daoyin, western medicine conventional therapy
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Cardiovascular Diseases, Cardiovascular Risk Factor
Physical Activity Intervention and Cardiovascular Risk Markers in COPD
The Aim of this study is to examine the feasibility of a future trial comparing the impact of a physical activity intervention and a standard pulmonary rehabilitation programme upon cardiovascular risk and symptoms in COPD.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, COPD
- Trial name
- PARC (NCT03869112)
- Testing
- Physical activity intervention, Pulmonary rehabilitation group
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University Hospitals, Leicester
COPD, Obstructive Pulmonary Disease
A Study to Evaluate the Effect of Yoga Exercises and Meditation on Lung Function and Quality of Life in COPD Patients.
The Investigator would like to study the effect of yoga exercises and meditation on lung volume, respiratory impedance, 6-minute walk distance and quality of life in COPD patients.
- Trial name
- NCT04020081
- Testing
- Yoga breathing exercises and Meditation
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Chest Research Foundation, India
Chronic Obstructive Pulmonary Disease
COPD Rehabilitation in Primary and Secondary Health Care
Pulmonary rehabilitation of COPD patients are implemented in a non-randomized manner in two settings: primary and secondary health care. The effect on quality of life and hospitalizations will be evaluated
- Trial name
- NCT00320333
- Testing
- pulmonary rehabilitation programme
- Where
- 2 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Chronic Obstructive Pulmonary Disease
COPE With COPD Trial
The overall objective of this study is to evaluate a collaborative self-management intervention in patients with moderate to severe COPD in a primary care population.
- Trial name
- NCT02343055
- Testing
- Case Management and Self-Management Education
- Where
- 4 sites in Canada
- Volunteers
- 182 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Obstructive Pulmonary Disease
Airway Inflammation, Symptoms and Lung Function in COPD
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease with high prevalence worldwide and with relevant impact on patient-related quality of life, morbidity and mortality.
- Trial name
- NCT01216592
- Testing
- COPD treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Ferrara
Tuberculosis, Chronic Obstructive Pulmonary Disease
Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium Tuberculosis
Identify a biologic (molecular) basis for the increased susceptibility of cigarette smokers to pulmonary TB (Mtb) by testing the hypothesis that smoking reprograms AM polarization towards a distinct phenotype associated with…
- Trial name
- NCT02021747
- Where
- Qatar
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Multiple Organ Failure, End Stage Cardiac Failure
Timing of Acute Palliative Care Consultation in Critically Ill Patients
A prospective randomized controlled trial studying the ordering of palliative care consultations in the emergency department (Ig) versus later palliative care consultations in the hospital--ICU or hospital ward(Cg).
- Conditions
- Multiple Organ Failure, End Stage Cardiac Failure, End Stage Chronic Obstructive Airways Disease, Chronic Kidney Disease Stage 5
- Trial name
- NCT02858778
- Testing
- Early order of palliative care consultation
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Chronic Obstructive Pulmonary Disease, Multiple Comorbidity
Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities
Many patients with chronic obstructive pulmonary disease (COPD) also have other diseases referred to as comorbidities. Often these patients require health care by a variety of health care professionals from services linked to…
- Trial name
- PICCOPD+ (NCT01648621)
- Testing
- 40 minute standardized education session, Individualized action plan, Individualized care plan
- Where
- 2 sites in Canada
- Volunteers
- 470 people
- Sponsor
- Michael Garron Hospital
Chronic Pulmonary Obstruction
Thread-Embedding Acupuncture for Functional and QoL Improvement in COPD Patients
The goal of this clinical trial is to learn if thread-embedding acupuncture (TEA) can improve functional capacity and quality of life of chronic pulmonary disease (COPD) patients.
- Trial name
- NCT06948578
- Testing
- Thread embedding-acupuncture
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Indonesia
Chronic Obstructive Pulmonary Disease
Personalized Variable Versus Fixed Dose Glucocorticoid Therapy in AECOPD
The hypothesis is that in acute exacerbated Chronic Obstructive Pulmonary Disease (AECOPD), personalized variable dose glucocorticoid treatment will result in superior clinical outcome when compared to fixed dose therapy.
- Trial name
- NCT02147015
- Testing
- Glucocorticoids, Antibiotics, Inhaled corticosteroid (ICS)
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Pulmonary Disease, Chronic Obstructive
A Comparison of 18g of Tiotropium Inhalation Capsules Once Daily and Atrovent Metered Dose Inhaler (2 Puffs of 20g, 4 Times Daily) in a Double-Blind, Double-Dummy, Efficacy and Safety Study in Adults With Chronic Obstructive Pulmonary Disease (COPD)
The objective of this study is to compare the bronchodilator efficacy and safety of once daily dosing of tiotropium inhalation capsules (18 ?g) and Atrovent? MDI (2 puffs of ipratropium bromide 20 ?g four times daily) in patients…
- Trial name
- NCT00239434
- Testing
- tiotropium inhalation powder capsule, ipratropium bromide Metered Dose Inhaler
- Where
- 6 sites in China
- Volunteers
- 200 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease, Community-acquired Pneumonia
A Pre-post Intervention Study Evaluating Home-based Management of Patients With COPD or CAP
Risk of rehospitalization within 30 days of discharge is higher than 20% in patients with chronic obstructive pulmonary disease (COPD) and up to 20% for patients with community acquired pneumonia (CAP).
- Trial name
- NCT05009485
- Testing
- Current Health platform
- Sponsor
- Current Health
Chronic Obstructive Pulmonary Disease
Electronic Cigarette-derived Oxidants and Cardiopulmonary Effects
This is a pilot study on the impact of switching from cigarettes to Electronic Cigarettes (EC) on disease-related clinical symptoms and biomarkers of harm in smokers with preexisting Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT05239793
- Testing
- NJOY e-cigarette
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
Chronic Obstructive Pulmonary Disease
Safety Study to Evaluate MN-221 in Chronic Obstructive Pulmonary Disease (COPD) Patients
In MediciNova's clinical development plan for MN-221, it was recognized that treatment of COPD exacerbations may necessitate more than one single i.v.
- Trial name
- NCT01551316
- Testing
- MN-221
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- MediciNova
Chronic Obstructive Pulmonary Disease Severe, Muscle Weakness
Additional Manual Therapy Over Inspiratory Muscle Training in COPD
The benefits of inspiratory muscle training(IMT) in patients with chronic obstructive pulmonary disease(COPD) were reported.But in severe COPD patients, benefit from IMT may be limited.There is need for further research in new…
- Trial name
- NCT04533516
- Testing
- Manual therapy technics, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
COPD
Effect of Exercise Training on Salivary Immunoglobulin A in Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether whole body exercise training alters the immunity in the lungs of people with COPD and reduces the incidence of chest infections over the longer term.
- Trial name
- NCT04604717
- Testing
- Pulmonary rehabilitation
- Where
- 2 sites in Australia
- Volunteers
- 35 people
- Sponsor
- Bayside Health
Chronic Obstr Lung Disease
Serum Interleukin 6 in Chronic Obstructive Pulmonary Disease
The aim of this study is to estimate level of IL 6 in COPD patients and its relation to COPD severity and acute exacerbation.
- Trial name
- NCT05214508
- Testing
- interleukin 6
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
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