Clinical trials: Chronic Pulmonary Obstruction
Chronic Obstructive Pulmonary Disease
An Evaluation of Web Based Pulmonary Rehabilitation
The purpose of this pilot study is to compare a six week web-based pulmonary rehabilitation programme with traditional hospital-based pulmonary rehabilitation classes for people affected by COPD.
- Trial name
- webbasedPR (NCT02404831)
- Testing
- Web-based PR, Hospital-based PR
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Glasgow
Chronic Obstructive Pulmonary Disease (COPD)
Phase IV O2 Consumption Study in COPD Patients.
A Phase IV study evaluating changes in oxygen consumption and cardiac function in Subjects with Chronic obstructive pulmonary disease (COPD) with resting hyperinflation after administration of Symbicort pMDI 160/4.5 μg.
- Trial name
- NCT02533505
- Testing
- Budesonide 160 mcg and formoterol fumarate dihydrate 4.5 mcg Inhalation aerosol
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease, Takotsubo Cardiomyopathy
Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital
The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these…
- Conditions
- Chronic Obstructive Pulmonary Disease, Takotsubo Cardiomyopathy, Acute Heart Failure
- Trial name
- CATCH (NCT06597331)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Sahlgrenska University Hospital
Pulmonary Disease, Chronic Obstructive
Combivent® HFA-propelled Compared to CFC-propelled Metered Dose Inhaler in Patients With COPD (Chronic Obstructive Pulmonary Disease)
Study to evaluate the safety of combivent delivered in two different formulations (hydrofluoroalkane (HFA) or chlorofluorocarbon (CFC)) from a metered dose inhaler (MDI), using a cumulative dose response model in patients with…
- Trial name
- NCT02182869
- Testing
- Combivent® HFA inhalation aerosol, Combivent® CFC inhalation aerosol
- Volunteers
- 7 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
Osteoprotegerin (OPG) in Induced Chronic Obstructive Pulmonary Disease (COPD) Sputum
Evaluation of OPG level as disease markers has also been reported. It has been showed that patients with coronary artery disease had higher serum OPG levels than healthy volunteers.
- Trial name
- NCT00655954
- Testing
- Induced sputum
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Chronic Obstructive Pulmonary Disease
A Pilot Study to Evaluate a Telepharmacy Intervention to Improve Inhaler Adherence in Veterans With COPD
Hypothesis: Can a counseling intervention, delivered by a pharmacist, increase inhaler adherence in veterans with COPD who have demonstrated poor inhaler adherence through pharmacy refill records? Veterans who receive who receive…
- Trial name
- NCT01270594
- Testing
- COPD Inhaler Counseling, Usual Pharmacy Care
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Wisconsin, Madison
Chronic Obstructive Pulmonary Disease
COPD Breathing Record Study 2
The aim of this study is to collect capnometric (tidal breathing CO2) data using TidalSense's N-Tidal C Data Collector Device. The data collected will be examined for correlation with currently accepted assessment techniques for…
- Trial name
- CBRS2 (NCT03615365)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- TidalSense
Chronic Obstructive Pulmonary Disease
The Oxidative Stress, Inflammatory Markers, and Metabolomics Response to Exercise in Patients With COPD
The effect of different physical exercise protocols on inflammatory markers, antioxidant balance, and metabolomics has not been fully elucidated.
- Trial name
- NCT04117412
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Hacettepe University
Copd, Obese
COPD in Obese Patients
The study included 176 patients with COPD. The first group included 88 normal weight patients with COPD: 71 men and 17 women, mean age 62.40 ± 8.83 years.
- Conditions
- Copd, Obese, Obesity, Abdominal
- Trial name
- NCT04105075
- Where
- Russia
- Volunteers
- 176 people
- Sponsor
- Voronezh N.N. Burdenko State Medical Academy
Chronic Obstructive Pulmonary Disease
Inhaled Corticosteroids (ICS) on Pulmonary Endothelial Function in COPD
The study objective is to determine whether an ICS added for 4 weeks to a baseline treatment with a Long-Acting Beta-adrenergic Agonist (LABA) and Long-Acting Muscarinic Antagonist (LAMA) combination improves pulmonary vascular…
- Trial name
- NCT05607719
- Testing
- Bevespi, Bretzri
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Miami
COPD
Effect of Aclidinium/Formoterol on Nighttime Lung Function and Morning Symptoms in Chronic Obstructive Pulmonary Disease
A number of studies have documented poor sleep quality and troublesome symptoms (breathlessness, cough and sputum production) upon awakening in patients with COPD.
- Trial name
- NCT02429765
- Testing
- ACL/FOR
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Queen's University
Lung Cancer Prevention
Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease
RATIONALE: Chemoprevention is the use of certain substances to keep cancer from forming, growing, or coming back. The use of green tea or polyphenon E may prevent cancer from forming in former smokers with chronic obstructive…
- Trial name
- NCT00363805
- Testing
- green tea, Polyphenon E
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Sherry Chow
Chronic Obstructive Pulmonary Disease
Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial
Background: Informative and supportive nursing care is essential to reduce complications and improve outcomes in Chronic Obstructive Pulmonary Disease (COPD) patients treated with Non-Invasive Ventilation (NIV).
- Trial name
- NCT04834037
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Chronic Obstructive Pulmonary Disease Exacerbation
The CATALINA Study
The CATALINA study is a prospective cohort study embedded within CICERO (Collaboration In COPD ExaceRbatiOns, a European Respiratory Society supported Clinical Research Collaboration), designed to collect standardised…
- Trial name
- NCT05008081
- Where
- 22 sites in Austria, Belgium and 9 more
- Volunteers
- 1,000 people
- Sponsor
- Wim Janssens
Chronic Obstructive Pulmonary Disease (COPD)
An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.
This is a research study to evaluate the efficacy and safety of the investigational drug Mitiperstat (AZD4831) in adult patients with chronic obstructive pulmonary disease.
- Trial name
- CRESCENDO (NCT05492877)
- Testing
- Mitiperstat (AZD4831)
- Where
- 101 sites in United States, Argentina and 12 more
- Volunteers
- 381 people
- Sponsor
- AstraZeneca
COPD
Study to Assess the Safety and Efficacy of PT010, PT003, and PT009 in Japanese Subjects With COPD Compared With Symbicort® Turbohaler®
A Randomized, Double-Blind, Parallel Group, 28-Week Chronic Dosing, Multi-Center Long-term Extension Study to Assess the Safety and Efficacy in Japanese Subjects with Moderate to Very Severe Chronic Obstructive Pulmonary Disease…
- Trial name
- NCT03262012
- Testing
- BGF MDI (PT010), GFF MDI (PT003), BFF MDI (PT009)
- Where
- 79 sites in Japan
- Volunteers
- 416 people
- Sponsor
- Pearl Therapeutics, Inc.
Chronic Obstructive Pulmonary Disease, Emphysema
Home-based Health Management of Chronic Obstructive Lung Disease (COPD) Patients
Regular physical activity has been found to be important in maintaining health and well-being in people with COPD. The purpose of this study is to test new technology and health coaching aimed to help people with COPD become more…
- Conditions
- Chronic Obstructive Pulmonary Disease, Emphysema, Pulmonary Rehabilitation
- Trial name
- NCT02999685
- Testing
- Home-base Pulmonary Rehab with Health Coaching
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Mayo Clinic
Chronic Obstructive Pulmonary Disease
Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease
REVASC is a randomized, double-blind, placebo-controlled study which will involve 150 patients with chronic bronchitis and COPD diagnosed cardiovascular disease.
- Trial name
- REVASC (NCT01595750)
- Testing
- Roflumilast 500
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Spanish Research Center for Respiratory Diseases
Chronic Obstructive Pulmonary Disease
Real-life Effectiveness and Cost-effectiveness of Qvar Versus FP and BDP in the Management of COPD
The objective of this study is to compare the effectiveness, cost-effectiveness and direct healthcare costs of managing chronic obstructive pulmonary disease (COPD) in primary care patients with evidence of COPD who either…
- Trial name
- QvarCOPD (NCT01141452)
- Testing
- Extra-fine hydrofluoroalkane beclomethasone MDI, Chlorofluorocarbon beclomethasone metered dose inhaler, Fluticasone propionate metred dose inhaler
- Where
- United Kingdom
- Volunteers
- 815,377 people
- Sponsor
- Research in Real-Life Ltd
Respiratory System Disease, Chronic Obstructive Pulmonary Disease
The Study for Evaluating the Clinical Effectiveness and Safety of Respiratory Rehabilitation Software 'Redpill Breath'(COPD, Asthma, Lung Cancer, Etc.)
The purpose of the study is to prove the clinical superiority of respiratory rehabilitation software "Redpill Breath" and evaluate the clinical improvement effect by 6-minute walk test of the software, compared to the manual…
- Conditions
- Respiratory System Disease, Chronic Obstructive Pulmonary Disease, Asthma Copd, Lung Cancer
- Trial name
- NCT05299385
- Testing
- Conventional rehabilition treatment(e.g leaflet) educated by hospital, Digital treatment based on Respiratory Rehabilitation Software
- Where
- 3 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Lifesemantics Corp.
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