Clinical trials: Chronic Rhinitis, active
Allergic Rhinitis, Chronic Rhinitis
Laser Posterior Nasal Nerve Neurolysis
This clinical trial aims to learn if laser posterior nasal nerve neurolysis can treat chronic rhinitis in adults. It will also learn about the safety of laser posterior nasal nerve neurolysis.
- Conditions
- Allergic Rhinitis, Chronic Rhinitis, Rhinorrhea, Sneezing
- Trial name
- LPN3 (NCT07050992)
- Testing
- Laser posterior nasal nerve neurolysis
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chiayi Christian Hospital
Chronic Rhinitis
NEUROMARK Registry Study
The NEUROMARK Registry Study is a prospective, multicenter, single-arm, post-market, interventional registry study to collect real-world evidence of the NEUROMARK System in subjects with chronic rhinitis.
- Trial name
- NCT05937308
- Testing
- NEUROMARK System
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- Neurent Medical
Chronic Sinusitis, Acute Sinusitis
Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis:
This double-blind, randomized controlled trial (BEE-SONIC) aims to evaluate the efficacy of bee venom phonophoresis in the treatment of chronic sinusitis.
- Conditions
- Chronic Sinusitis, Acute Sinusitis, Rhinosinusitis
- Trial name
- BEE-SONIC (NCT07151313)
- Testing
- Bee Venom Phonophoresis, Standard Care (oral decongestants + saline nasal irrigation)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sinai University
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Nasal Obstruction
Nasal Obstruction With Oxymetazoline and Corticosteroids
This study aims to examine the efficacy and safety of commination oxymetazoline/intranasal steroids for long-term management of chronic nasal obstruction that is recalcitrant to the current standard of care.
- Trial name
- NORTOC (NCT06830109)
- Testing
- Oxymetazoline Nasal Spray, Budesonide nasal spray
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Washington University School of Medicine
Chronic Rhinitis
A Study to Evaluate Treating Watery Noses With Cryotherapy in the Clinic Setting. This is Cold Therapy, Freezing the Issues at the Back of the Nose to Ease Symptoms.
Adult patients presenting with rhinitis who have persistent rhinitis despite appropriate medical treatment will receive a session of cryotherapy for the nose.
- Trial name
- Cryotherapy (NCT07917091)
- Testing
- Cryotherapy alone
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- East and North Hertfordshire NHS Trust
Chronic Rhinitis, Non-allergic Rhinitis
A Randomized Controlled Trial Comparing Posterior Nasal Nerve Ablation Procedures for Chronic Rhinitis
The goal of this clinical trial is to learn which procedural intervention most effectively reduces symptoms of chronic rhinitis (non-allergic rhinitis) in adult patients (18 years and older).
- Trial name
- NCT07706595
- Testing
- RhinAer, Neuromark, Clarifix
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Type 1 Diabetes, Asthma
EmoTIChealth: Promoting Adolescent Health Through a Serious Game.
The intervention program targets adolescents between 12 and 16 years of age. The intervention program is designed for adolescents during a critical developmental stage marked by significant life transitions, where building strong…
- Conditions
- Type 1 Diabetes, Asthma, Allergic Rhinitis, Food Allergy
- Trial name
- NCT07212530
- Testing
- EmoTIChealth
- Where
- Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Chronic Allergic Rhinitis
Safety and Tolerability of Fluticasone Propionate 10% Nasal Insert in Participants With Chronic Allergic Rhinitis
Phase 1 study designed to evaluate the safety, tolerability and Pharmacokinetic (PK) of a fluticasone propionate (FP) 10% nasal insert in adults suffering from persistent allergic rhinitis.
- Trial name
- NCT07918404
- Testing
- Fluticasone Propionate (FP) 10% Nasal Insert
- Volunteers
- 25 people
- Sponsor
- Dianosic
Chronic Rhinitis
The Epidemiological and Intrinsic Characteristics of Chronic Rhinitis
Chronic rhinitis affects 10-40% of China's population, or over 300 million people, and can lead to respiratory and psychological issues.
- Trial name
- NCT06370468
- Testing
- Epidemiological investigation
- Where
- China
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Zheng Liu ENT
Chronic Rhinitis
Characteristic Transcriptomic, Proteomic and Metabolomic Molecular Studies of Nasal Secretions From Chronic Rhinitis
Chronic rhinitis is a common chronic nasal mucosal inflammatory disease. Its clinical symptoms and severity are diverse, mainly including allergic rhinitis, local allergic rhinitis, non-allergic rhinitis with hypereosinophilia…
- Trial name
- NCT06678334
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Allergic Rhinitis
Facilitating Surgical Choice in Patient With Chronic Hypertrophic Rhinitis Using a Patient Decision Aid
This study is a prospective randomized controlled trial that aims to enroll 158 patients diagnosed with chronic hypertrophic rhinitis who are candidates for inferior turbinate surgery.
- Trial name
- NCT07435714
- Testing
- Patient decision aid
- Where
- Taiwan
- Volunteers
- 158 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS)
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
- Conditions
- Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS), Rhinitis, Vasomotor, Thyroid Nodules
- Trial name
- NCT07299474
- Testing
- Lavender Aromatherapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Chronic Rhinosinusitis With Nasal Polyps
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
The main objective of this study is to evaluate treatment outcomes of tezepelumab among participants with physician-determined surgery-eligible CRSwNP, with or without asthma. Study details include: 1.
- Trial name
- ESSENCE (NCT06706817)
- Testing
- Tezepelumab
- Where
- 41 sites in United States, Bulgaria and 7 more
- Volunteers
- 181 people
- Sponsor
- AstraZeneca
URTI, Bronchiolitis
Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms
The purpose of this post-market clinical investigation is to assess in a real-life setting, the effectiveness, usage, tolerance, safety and satisfaction of 4 isotonic and hypertonic seawater-based CE-marked nasal sprays.
- Conditions
- URTI, Bronchiolitis, COVID - 19, Allergic Rhinitis
- Trial name
- SeaBridge (NCT07262450)
- Testing
- Respimer® Hygiene-Prevention -Baby, kids, adults, Respimer® Hygiene-Prevention Kids, adults, Respimer® Decongestion Baby, kids, adults
- Where
- 32 sites in France
- Volunteers
- 1,065 people
- Sponsor
- Laboratoire de la Mer
Rhinosinusitis
Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis
The purpose of this study is to determine if acquired (partial) Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) deficiency contributes substantially to the pathogenic mechanisms underlying Chronic Rhinosinusitis (CRS)…
- Trial name
- NCT02038166
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Nasal Obstruction, Chronic Rhinitis
Traditional vs. Posterior Nasal Radiofrequency Ablation for Chronic Rhinitis
This study is a prospective, single-center, single-blinded randomized controlled trial designed to compare the clinical effectiveness of traditional radiofrequency ablation of the anterior inferior turbinate alone versus expanded…
- Conditions
- Nasal Obstruction, Chronic Rhinitis, Nonallergic Rhinitis, Rhinorrhea
- Trial name
- NCT07323888
- Testing
- Traditional Radiofrequency Ablation of Inferior Turbinates With Posterior Nasal Radiofrequency Ablation, Traditional Radiofrequency Ablation of Inferior Turbinates
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chien Yu Huang
Chronic Rhinitis
Study on the Optimization of the Diagnostic Process for Chronic Rhinitis Using Nasal Allergen Provocation Test
Chronic rhinitis (CR) is one of the most prevalent global diseases, with studies estimating that up to 30% of the worldwide population is affected.
- Trial name
- NCT06999044
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Chronic Rhinosinusitis With Nasal Polyps, Allergic Rhinitis
Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps
During this project, the investigators want to explore in vitro changes in basal cells and the crosstalk with residing immune cells as potential pathogenic mechanisms in CRSwNP vs healthy controls by using surgically resected…
- Trial name
- NCT06129552
- Testing
- Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Rhinitis
Evaluation of Pulsed Field Ablation of the Posterior Nasal Nerve for Chronic Rhinitis
Evaluation of safety, effectiveness and tolerability of the Aventix Medical Device used for the treatment of chronic rhinitis
- Trial name
- NCT06598319
- Testing
- NOVOCLEAR™ Device
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Aventix Medical Inc.