Clinical trials: Chronic Rhinosinusitis (Diagnosis)
Chronic Sinusitis
Photodynamic Therapy for the Treatment of Chronic Rhinosinusitis
The purpose of this study is to determine whether the use of light and a topically applied photosensitizer can relieve symptoms and clinically improve patients with chronic rhinosinusitis.
- Trial name
- NCT01854619
- Testing
- Photodisinfection (antimicrobial photodynamic therapy, aPDT), Saline irrigation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Ondine Biomedical Inc.
Chronic Rhinosinusitis
Surgery Checklist and Process Improvement Surrounding Endoscopic Sinus Surgery
The purpose of this clinical trial is to evaluate the effectiveness of a new surgical checklist in the setting of sinus surgery for patients with chronic rhinosinusitis (CRS) and to measure the frequency of compliance by surgical…
- Trial name
- NCT01499719
- Testing
- Checklist introduction / Pause
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Rhino Sinusitis
Analysis of Hemostatic Agents Compared to Physiologic Hemostasis
This study is a prospective comparison between absorbable hemostatic agents as a group and the body's natural hemostatic ability without aid of therapy in patients undergoing bilateral sinus surgery with or without septoplasty.
- Trial name
- NCT03068728
- Testing
- Arista, Nexfoam, Nasopore
- Volunteers
- 62 people
- Sponsor
- St. Louis University
Sinusitis
Comparing the Use of Saline or Saline Plus Gentamycin in Nasal Irrigation to Treat Chronic Sinusitis in Children
Healthy children may develop symptoms of chronic sinusitis such as chronic cough, chronic runny nose, nasal congestion, even headaches.
- Trial name
- NCT00465530
- Testing
- Saline, Gentamycin
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Julie Wei, MD
Asthma, Chronic Rhinosinusitis
Analysis of Inflammation and Microbiome in Patients With Sinusitis and Asthma
This is a cross-sectional, non-interventional study, consisting of three study arms, (1) Full Characterization (AIMS-Full), (2) Surgery Arm (AIMS-OR), and (3) Mucus Collection (AIMS-M).
- Trial name
- AIMS (NCT02548598)
- Testing
- Endoscopic sinus surgery
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Chronic Rhinosinusitis (Diagnosis)
Use of Budesonide Diluted to Maximum Clinical Treatment of Patients With Chronic Rhinosinusitis With Polyoposis.
This is a double-blind, randomized, double-blind, randomized, double-blind, randomized block design with two intervention groups of 30 patients each.
- Trial name
- CRS (NCT05541419)
- Testing
- Budesonide Nasal
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Estadual de Londrina
Nasal Polyps, Chronic Rhinosinusitis
An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps
The overall purpose of this study is to evaluate the safety, efficacy, and durability of response of omalizumab in an open-label setting in adult participants with chronic rhinosinusitis with nasal polyps who completed the…
- Trial name
- NCT03478930
- Testing
- Omalizumab
- Where
- 79 sites in United States, Belgium and 12 more
- Volunteers
- 249 people
- Sponsor
- Hoffmann-La Roche
Chronic Sinusitis, Nasal Polyposis
FESS With or Without Intranasal Desmopressin in Chronic Rhinosinusitis With Nasal Polyps
Chronic rhinosinusitis with nasal polyps is a condition that causes long-lasting inflammation and swelling in the nose and sinuses and may lead to nasal blockage, nasal discharge, facial pressure, and reduced sense of smell.
- Trial name
- NCT07855315
- Testing
- Desmopressin Acetate Nasal, 10 μg/0.1 ml per spray, Functional Endoscopic Sinus Surgery
- Volunteers
- 174 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Chronic Rhinosinusitis (Diagnosis)
Botulium Toxin Type A In Non Infectious Chronic Rhinosinusitis
The present work aims to assess the effectiveness and safety of topical application of BTX - A compared with its intra turbinate injection in controlling the symptoms in non infectious chronic rhinosinusitis patients
- Trial name
- NCT04572516
- Testing
- BTX A Topical, BTX A Injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University