Clinical trials: Chronic Schizophrenia
Schizoaffective Disorder, Bipolar Type, Bipolar Disorder
Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues
Psychoneuromentalism Disorder is a disorder arising in the mind; that is related to the mental and emotional state of a person. It is the science of mental life. The body has a natural design to heal itself.
- Conditions
- Schizoaffective Disorder, Bipolar Type, Bipolar Disorder, ADHD - Combined Type, Dissociative Disorder
- Trial name
- PNMD (NCT06235177)
- Testing
- Decompartmentalization Framework, Liquid Herbal TInctures, Mental Imagery
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Essence of Integrative Health and Medicine Practice
Schizophrenia, Chronic Psychiatric Disorder
Mental Healthcare in Older Adults With Schizophrenia
As in the general population, there is a gradual and steady increase in life expectancy of patients with schizophrenia. But this increase is at a smaller scale, with a rate of premature death that is still 2 to 3 times higher…
- Trial name
- CSA (NCT02884739)
- Testing
- Data collection
- Where
- France
- Volunteers
- 685 people
- Sponsor
- CHU de Reims
Schizophrenia, Alcohol Abuse
Bone Density in Patients With Schizophrenia
People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis. To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol…
- Trial name
- NCT00540267
- Testing
- No Intervention
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Inje University
Schizophrenia
Pentoxifylline as an Adjunctive in Treatment of Negative Symptoms in Chronic Schizophrenia
The aim of this study to evaluate the efficacy and safety of pentoxifylline, the novel phosphodiesterase inhibitor, as an adjunctive to risperidone in alleviating the negative symptoms of schizophrenia.
- Trial name
- NCT04094207
- Testing
- Pentoxifylline
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sadat City University
Schizophrenia
Pharmacodynamic/Pharmacokinetic Study of AQW051 in Schizophrenia
Part 1 of the study will assess the enhancement of task-related brain activation (BOLD response) in key brain areas in schizophrenia during the performance of working memory, episodic memory and visual activation tasks as…
- Trial name
- NCT00825539
- Testing
- AQW051
- Where
- 7 sites in United States
- Volunteers
- 68 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Schizophrenia
An Open-Label Investigation of the Adjuvant Therapeutic Effects of Galantamine in Patients With Chronic Schizophrenia and Persistent Deficit Symptoms
The purpose of this study is to see if galantamine is an effective agent for the treatment of the cognitive abnormalities, negative symptoms, and /or behavioral impairments seen in schizophrenia.
- Trial name
- NCT00161044
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia
The Effect of Paliperidone Palmitate in Schizophrenia
The purpose of this study is the evaluation of effectiveness of paliperidone palmitate within three different group of schizophrenia patients.
- Trial name
- sustenna (NCT01860781)
- Testing
- paliperidone palmitate
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Chronic Schizophrenia
Memantine for the Treatment of Cognitive Dysfunction and Negative Symptoms in Patients With Chronic Schizophrenia
The purpose of this study is to evaluate the efficacy and safety of 24 weeks memantine add-on treatment to risperidone for the treatment of negative symptomatology and cognitive impairment in patients with chronic schizophrenia.
- Trial name
- NCT00148616
- Testing
- Memantine
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- M. Schaefer, MD
Schizophrenia
A Study to Evaluate the Effects of Once Daily Doses of AQW051 on Cognition, in Stable Schizophrenia Patients
This is a study in chronic stable Schizophrenia with the purpose to answer the question of whether agonism of the nicotinic alpha7 receptor is capable of enhancing cognition in a well defined chronic stable patient population…
- Trial name
- NCT01730768
- Testing
- AQW051
- Where
- 13 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novartis Pharmaceuticals
Schizophrenia, Central Nervous System Diseases
Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia
This study is being conducted to determine the safety and effect on cognitive function of two different doses of an investigational medication, EVP-6124, in individuals with schizophrenia who are on chronic stable atypical…
- Conditions
- Schizophrenia, Central Nervous System Diseases, Cognition
- Trial name
- NCT00968851
- Testing
- EVP-6124
- Where
- 31 sites in United States, Russia and 2 more
- Volunteers
- 317 people
- Sponsor
- FORUM Pharmaceuticals Inc
Chronic Schizophrenia
The Effect of Transcranial Direct Current Stimulation on Human Brains: A Neuroimaging Study
The purpose of this project is to examine brain function before, during, and after the administration of tDCS (Transcranial Direct Current Stimulation). The brain can perform its job well or poorly depending on many things.
- Trial name
- NCT02421146
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Schizophrenia
Bexarotene Augmentation of Antipsychotic Treatment for Chronic Schizophrenia
Background: Bexarotene (Targretin) is a synthetic retinoid mainly used for treatment of patients suffer from oncological or dermatological diseases.
- Trial name
- NCT00535574
- Testing
- Bexarotene (Targretin LGD1069), bexarotene
- Where
- 3 sites in Israel
- Volunteers
- 90 people
- Sponsor
- Beersheva Mental Health Center
Patients With Chronic Schizophrenia
The Effectiveness of Lower Extremity Strength Training
The increase in chronic schizophrenia patients with sarcopenia is currently an important healthcare issue in Taiwan and requires enhanced prevention and progress.
- Trial name
- LEST-CSchizo (NCT07183969)
- Testing
- lower limb muscle strength training program
- Where
- Taiwan
- Volunteers
- 78 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Schizophrenias, Psychoses
Sarcosine or D-Serine Add-on Treatment for Chronic Schizophrenia
Both GlyT-1 inhibitors and NMDA-glycine site agonists have been demonstrated to be beneficial for chronic schizophrenia patients.
- Conditions
- Schizophrenias, Psychoses, Psychotic Disorders, Schizophrenic Disorders
- Trial name
- NCT00491569
- Testing
- Sarcosine and D-serine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Chronic Disease, Mental Disorder
Reducing Cardiovascular Risk in Adults With Serious Mental Illness
This purpose of this study is to adapt, implement and test the ability of a sophisticated point-of-care electronic health record-based clinical decision support that identifies and prioritizes all available evidence-based…
- Conditions
- Chronic Disease, Mental Disorder, Health Behavior, Bipolar Disorder
- Trial name
- SMIWizard (NCT02451670)
- Testing
- Prioritized Clinical Decision Support
- Where
- 3 sites in United States
- Volunteers
- 10,347 people
- Sponsor
- HealthPartners Institute
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Schizophrenia
Efficacy of Chronic Disease Self-management Program in People With Schizophrenia
This was a randomized controlled behavioral intervention trial to assess the efficacy of investigating program of chronic disease self-management program in people on schizophrenia patients conditions of depression, activities of…
- Trial name
- NCT04503954
- Testing
- Chronic disease self-management program, General psychiatric intervention
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Smoking Behavior in Schizophrenia
Quetiapine Decreases Smoking in Patients With Chronic Schizophrenia
A single-blind switching study in which forty subjects currently being treated with risperidone will be randomly assigned to either stay on risperidone or switched to quetiapine.
- Trial name
- NCT00231101
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Arthur P. Noyes Research Foundation
Schizophrenia
High Frequency rTMS Treatment for Cognitive Impairments in Chronic Schizophrenia Patients
A randomized, double-blind sham-controlled trial of high frequency rTMS treatment for cognitive impairments in 120 chronic schizophrenia patients
- Trial name
- NCT03774927
- Testing
- 10 Hz treatment group, 20 Hz treatment group, Control Group
- Volunteers
- 120 people
- Sponsor
- Beijing HuiLongGuan Hospital