Clinical trials: Chronic Spine Pain
Spine Injuries and Disorders, Pain, Chronic
Real-Time Accurate Pathology Inspection and Decompression Study
The primary objective is changes in spine and lower limb pain following a laser-assisted neural decompression (LAND) procedure for the treatment of lumbar, thoracic, or cervical spine and/or extremity pain.
- Conditions
- Spine Injuries and Disorders, Pain, Chronic, Pain, Back, Pain, Neck
- Trial name
- RAPID (NCT05347108)
- Testing
- laser-assisted neural decompression (LAND) procedure
- Where
- United States
- Sponsor
- KM Clinical Research Group
Postoperative Pain, Neuropathic Pain
Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement
Spinal surgery is associated with intense pain and associated to a history of preoperative chronic pain. Pregabalin is licensed to treat chronic neuropathic pain, particularly when high dose of opioid are required.
- Trial name
- PREGAB (NCT02866396)
- Testing
- Pregabalin, Naive patient
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Christophe Aveline, MD
Chronic Pain
Monopolar Dielectric Diathermy by Radiofrequency and Therapeutic Exercise in Patients With Chronic Low Back Pain.
A total of 60 people diagnosed with non-specific chronic low back pain of more than 3 months of evolution and who are not currently undergoing any type of treatment will be recruited, with ages between 30 and 65 years.
- Trial name
- NCT05149690
- Testing
- Experimental: monopolar dielectric diathermy and supervised therapeutic exercise, Active Comparator: Supervised therapeutic exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Almeria
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Opioid Dependence, Chronic Pain
Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery
The goal of this study is to determine whether comprehensive perioperative administration of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine can increase postoperative pain tolerance and reduce opiate consumption in…
- Trial name
- NCT04220489
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jacques E. Chelly
Chronic Low Back Pain, Physiotherapy
Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 2)
The purpose of this study is to investigate the effect on QoL, PI and the AROM° in patients with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain, Physiotherapy, Quality of Life, Range of Motion
- Trial name
- CLBP (NCT03309540)
- Testing
- Physioterapy intervention
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Musculoskeletal Pain
Returning to Work. Efficacy of "Tailored Physical Activity or" "Chronic Pain Self-management Program" in Sicklisted Citizens With Chronic Musculoskeletal Pain
TEst the effect of "Tailored Physical Activity" or "Chronic Pain Self-management Program" on Returning to Work in Sicklisted Citizens With Chronic Pain Related to the Spine or Upper Body
- Trial name
- NCT01356784
- Testing
- Tailored Physical Activity, "Chronic Pain Self-management Programme", Health counselling
- Where
- Denmark
- Volunteers
- 141 people
- Sponsor
- University of Southern Denmark
Low Back Pain
Non Pain Contingent Spine Rehabilitation Therapy in Chronic Low Back Pain
The aim of study is to determine effects of non pain contingent spine rehabilitation in chronic low back pain.A Randomized controlled trial will be conducted at Railway general hospital.
- Trial name
- NCT04619134
- Testing
- NCSR Program, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Whiplash Injury of Cervical Spine, Osteopathia
The Effectiveness of Osteopathic Treatment in Cervical Whiplash.
Introduction. Whiplash is common after road traffic accidents and affects millions of people worldwide; 50% develop chronic symptoms and 15% have their ability to work compromised.
- Conditions
- Whiplash Injury of Cervical Spine, Osteopathia, Quality of Life, Chronic Pain Syndrome
- Trial name
- NCT06334978
- Testing
- Osteopathic intervention
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Back Pain, Neck Pain
Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain
HYPTHOTHESIS: The researchers hypothesize that application of active magnetic therapy vs. sham utilized while individuals sleep can reduce neuropathic pain in the spine and improve the quality of sleep.
- Conditions
- Back Pain, Neck Pain, Sleep Initiation and Maintenance Disorders
- Trial name
- SLEEP/MAG (NCT00445133)
- Testing
- Magnetic Sleep Pad
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Chronic Back Pain
Assessing Spinal Pain With an Artificial Intelligence-assisted Whole Body Electrical Stimulation Device
The goal of this observational study is to investigate the correlation between self-reported pain and the measurements obtained using an artificial intelligence-assisted whole-body electrical stimulation device (StimaWELL 120MTRS…
- Trial name
- NCT07244237
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Amasya University
Low Back Pain, Musculoskeletal Pain
Regional Manual Therapy and Motor Control Exercise for Chronic Low Back Pain
Purpose: The primary purpose of this study is to determine whether or not the addition of thoracic, pelvic, and hip manual therapy to a standard physical therapy (PT) approach consisting of motor control exercises and lumbar…
- Trial name
- NCT02170753
- Testing
- Regional manual therapy, Standard physical therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Texas Southwestern Medical Center
Degenerative Lumbar Spine Disease
Combination Therapy With Atelocollagen in Epidural Nerve Block
"In this study, the investigators plan to evaluate muscle mass and pain relief 4 weeks after performing epidural nerve block and Type I porcine atelocollagen injection into multifidus muscle in patients with chronic low back pain…
- Trial name
- NCT05014945
- Testing
- (atelocollagen group)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Gangnam Severance Hospital
Low Back Pain, Low Back Ache
Measuring Reliability of Spine Mobilization in Low Back Pain
This observational study aims to learn how to measure joint motion and tissue response when pressure is applied to the back and examine how the nervous system responds to the applied pressure.
- Conditions
- Low Back Pain, Low Back Ache, Low Back Pain, Mechanical, Low Back Pain, Posterior Compartment
- Trial name
- NCT07582705
- Testing
- Spinal mobilization
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Back Pain With Radiation, Pain, Postoperative
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT03546738
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- St. Olavs Hospital
Whiplash Injuries
Maastricht Neck Study: Cervical Range of Motion in Whiplash Patients
Rationale: Neck complaints are often caused by motor vehicle accidents and particular after rear-end collision. Patients complain about neck pain after a whiplash trauma, which lead to mobility restrictions of the cervical spine.
- Trial name
- MaNeS (NCT00952510)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University Medical Center
Musculoskeletal Pain, TMJ Pain
Association of Jaw Dysfunction With Neck Disability in Subjects With Chronic Cervical Spine Disorders
Since TMJ and cervical pain incidence are rising and both structures are highly interrelated anatomically and functionally. And yet no standard protocol for TMD therapy The objective of this study is to state if there is a…
- Conditions
- Musculoskeletal Pain, TMJ Pain, Cervical Pain
- Trial name
- NCT04849442
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Chronic Spinal Pain
Turkish Validation of the 9-Item Tampa Scale of Kinesiophobia
This observational methodological study aims to evaluate the validity and reliability of the Turkish version of the 9-item Tampa Scale of Kinesiophobia (TSK-9) in individuals with chronic spinal pain.
- Trial name
- NCT07673159
- Testing
- Questionnaire-based assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Akdeniz University
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Back Pain, Neck Pain
Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain
Implementing workplace strategies to manage symptoms in office workers with chronic nonspecific spinal pain (CNSP) may improve both health- and work-related outcomes, as adherence to these interventions is more feasible in this…
- Conditions
- Back Pain, Neck Pain, Low Back Pain
- Trial name
- NCT07251959
- Testing
- Exercise therapy, Manual Therapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Catholic University of Murcia