Clinical trials: Chronic Spine Pain
Acute Low Back Pain, Chronic Low Back Pain (CLBP)
Exploring Multidimensional Trajectories in People With Low Back Pain
Low back pain (LBP) is a major health problem in Switzerland and worldwide. Globally, LBP remains the leading cause of years lived with disability and its incidence and associated socioeconomic consequences are predicted to…
- Trial name
- NCT07176845
- Testing
- Observational
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- Bern University of Applied Sciences
Chronic Spinal Pain
RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain
Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments.
- Trial name
- NCT05840354
- Testing
- Magstim Rapid2
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lumbar Degenerative Disc Disease, Lower Back Pain
Human Autograft Mesenchymal Stem Cell Mediated Stabilization of The Degenerative Lumbar Spine
Investigate the potential of tissue grafting that includes human mesenchymal stem cells in the repair and potential stabilization of the degenerative Lumbar disk and facet joint denovo and at the time of surgical reconstruction.
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Trial name
- NCT02529566
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
Low Back Pain
Assessment of All Spine Segments ın Individuals With Low Back Pain
The aim of the study is to evaluate the kinematics of all spine segments in 3 planes and compare them with asymptomatic controls using wearable technology while performing functional tasks that patients with chronic low back pain…
- Trial name
- NCT06276322
- Testing
- Low back pain group, Healthy group
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware
Chronic Pain
Effects of Electrotherapy on Pain, Anxiety, Motion and Disability in Adults With Neck or Upper Body Pain.
This will be a prospective randomized controlled trial with sixty adults, 20 to 40 years of age. There will be three groups as follows: the normal group, control group, and intervention group where subjects will receive…
- Trial name
- NCT05382039
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Back Pain
Influence of Verbal Suggestion on the Therapeutic Effect of the Joint Manipulation
The aim of the study is to evaluate the influence of verbal suggestion on the therapeutic effect of the joint manipulation of the lumbar spine in patients with chronic non-specific low back pain in relation to the pain level…
- Trial name
- NCT06537739
- Testing
- Lumbar manipulation, Negative communication - nocebo, Neutral communication
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- John Paul II University in Biała Podlaska
Chronic Low Back Pain
Stanford Spine Keeper - Managing Your Low Back Pain
Mobile health applications (mHealth apps) are transforming medical research and intervention by allowing constant, instantaneous and personalized access to patients.
- Trial name
- NCT05443503
- Testing
- Mobile health applications (mHealth apps) based intervention
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sacroiliac Joint Pain
Peripheral Nerve Stimulation for Treatment of Sacroiliac Joint Pain
Prospective randomized controlled study, primary objective: Pain reduction in patients with chronic Sacroiliac joint pain after therapy either with Peripheral Nerve Stimulation or with best medical treatment.
- Trial name
- SIlencing (NCT05357300)
- Testing
- Peripheral Nerve Stimulation
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- PD Dr. med. Simon Bayerl
Pain, Musculoskeletal Manipulations
Effects of a Protocol of Hip Flexor Stretching on Chronic Mechanical, Non-specific LBP.
The goal of this clinical trial is to compare the effectiveness of a stretching, exercise and education protocol versus usual care in improving pain, function and disability in patients with non-specific mechanical chronic low…
- Conditions
- Pain, Musculoskeletal Manipulations, Low Back Pain, Mechanical
- Trial name
- HipFlexinCLBP (NCT06975345)
- Testing
- Multicomponent intervention. Hip flexors stretching, Strengthening exercises and education and medical treatment (Medication and medical counselling), Medical treatment.
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Back Pain With Radiation, Pain, Postoperative
Burst Crossover Trial
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT05372822
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- St. Olavs Hospital
Physical Therapy, Chronic Low Back Pain
Effect of Physiotherapeutic Interventions on Quality of Life in Patients With Chronic Low Back Pain. (Study 1)
The purpose of this study is to investigate the effect on QoL, PI and the AROM° in patients with non-specific chronic low back pain.
- Conditions
- Physical Therapy, Chronic Low Back Pain, Quality of Life, Range of Motion
- Trial name
- CLBP (NCT03322956)
- Testing
- Physioterapy intervention
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Facet Syndrome of Lumbar Spine
Safety and Initial Feasibility of Using the Neurolyser XR Device for the Treatment of Axial Chronic Low Back Pain
Single arm pilot study to evaluate the safety and initial feasibility of the Neurolyser XR, a high intensity focused ultrasound device, for non-invasive treatment of axial chronic low back pain
- Trial name
- NCT04129034
- Testing
- Neurolyser XR
- Where
- 5 sites in Canada
- Volunteers
- 30 people
- Sponsor
- FUSMobile Inc.
Pain
Perioperative Pain Management In Spine Surgery Patients: Part I
The purpose of this study is a comparison of pain management in opioid-tolerant spine surgery patients using a perioperative dosing goal of 150% of patient's baseline oral morphine equivalent (OME), as compared to standard…
- Trial name
- NCT01447888
- Testing
- 150% Oral Morphine Equivalent (OME), Clinical Judgment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Allina Health System
Anesthesia, Analgesia
Pectoral Nerve Block II and Erector Spine Plane Block in Breast Cancer Surgery
This study evaluates the analgesic effects of pectoralis nerve block (PECS II) and erector spinae plane block (ESP) in patients having segmental mastectomy and sentinel lymph node biopsy (SLNB).
- Conditions
- Anesthesia, Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04135157
- Testing
- Pectoralis nerve block II, Erector spine plane block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ondokuz Mayıs University
Low Back Pain
Global Posture Reeducation (GPR) Compared To Isostretching in Chronic Low Back Pain Patients
The aim of this study was to investigate the changes in posture, flexibility, muscle strength, functional capacity, heart rate(HR), peripheral oxygen saturation, systolic blood pressure, diastolic blood pressure and intensity of…
- Trial name
- NCT01468298
- Testing
- Isostretching, Global Posture Reeducation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centro Universitario de Maringa
Postoperative Pain, Lumbar Surgery
Retrolaminar Analgesia for LuMbar Surgery
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine…
- Conditions
- Postoperative Pain, Lumbar Surgery, Back Pain Lower Back Chronic, Opioid Analgesia
- Trial name
- REALM (NCT07334288)
- Testing
- Ultrasound-Guided Retrolaminar Block, Standard Analgesia
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Universidad de los Andes, Chile
Chronic Ankle Injuries, Chronic Low-back Pain
Ankle Spine Syndrome "RAFFET Syndrome II
A case series aimed to describe a new clinical condition for the first time in the medical literature called Ankle Spine Syndrome or "RAFFET Syndrome II".
- Conditions
- Chronic Ankle Injuries, Chronic Low-back Pain, Lumbar Disc Herniation, Calf Muscle Weakness
- Trial name
- NCT06140862
- Testing
- calf muscle strengthening and streching
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Noha Khaled Shoukry
Chronic Low Back Pain
Lower Back Biomechanics in Veterans With Non-Specific Low Back Pain
Low back pain (LBP) is strongly associated with opioid consumption among Veterans, and improved clinical management of LBP is likely to reduce reliance on opioid among Veterans.
- Trial name
- NCT04249453
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Low Back Pain
Alleviating Trunk Low Back Pain, With an Active Medical Device Study (ATLAS)
The aim of the study is to evaluate the reduction of pain by wearing the ATLAS Medical Device in standardized daily activities for patients with Chronic Low Back Pain.
- Trial name
- ATLAS (NCT03801941)
- Testing
- wearing ATLAS device during evaluation at 4th day, wearing ATLAS device during evaluation at 5th day
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Lille