Clinical trials: Chronic Stress, open to volunteers
Fibromyalgia, Fibromyalgia (FM)
The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients
The goal of this clinical trial is to learn if a traditional grape-based fermented drink called hardaliye helps treat fibromyalgia in adult women.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome, Primary
- Trial name
- NCT07403929
- Testing
- Medical Nutrition Therapy (MNT), Hardaliye (200 mL/day)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Chronic Pain, PTSD - Post Traumatic Stress Disorder
Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans
Veterans in Canada are twice as likely as the general population to experience chronic pain. This pain is often linked to post-traumatic stress disorder (PTSD), and both have a major impact on their quality of life.
- Conditions
- Chronic Pain, PTSD - Post Traumatic Stress Disorder, Quality of Life (QOL)
- Trial name
- VR & CN-NINM (NCT07137845)
- Testing
- Virtual reality, Cranial nerve non-invasive neuromodulation (CN-NINM)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Chronic Pelvic Pain Syndrome (CPPS), Radiation-Induced Disorder
Gene and Molecular Pathways of Ozone Treatment Response in Gynecological Tumor Patients With Chronic Pelvic Pain Secondary to Cancer Treatment
Gynecological cancers, including those affecting the ovaries, uterus, and cervix, represent a significant health burden for women.
- Conditions
- Chronic Pelvic Pain Syndrome (CPPS), Radiation-Induced Disorder, Radiotherapy Side Effects, Side Effect of Chemotherapy
- Trial name
- OzoGynEpigen (NCT06816095)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Bernardino Clavo, MD, PhD
Stress, Psychological
Functional Foods for Health
The gut plays an important role in supporting the immune system, and certain dietary components such as probiotics (beneficial bacteria) and prebiotics (fibres that feed beneficial bacteria) can help to maintain gut and immune…
- Trial name
- NCT07871682
- Testing
- Sodium alginate
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Chronic Migraine, Headache
Comprehensive Approach to Lifestyle Modification in Chronic Migraine
Migraine is a highly prevalent neurological disorder and one of the leading causes of disability worldwide, substantially affecting quality of life and individuals during their most productive years.
- Trial name
- CALM-Migraine (NCT07802860)
- Testing
- Comprehensive Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Pregnancy
Mitigating Response to Stressors in Pregnant Women
Stress-induced pregnancy complications are significant contributors to preterm labor as well as maternal and perinatal morbidity and mortality.
- Trial name
- NCT06718907
- Testing
- Simulated stimuli, Stress Management
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Chronic Kidney Diseases
miRNA in Chronic Kidney Diseases
Oxidative stress and endoplasmic reticulum (ER) stress play a key role in tubular damage in both acute kidney injury and chronic kidney disease (CKD).
- Trial name
- NCT06316284
- Where
- Croatia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
COPD (Chronic Obstructive Pulmonary Disease)
Effect of Silymarin as Add on Therapy on Oxidative Stress, Pulmonary Function and Quality of Life in Stable COPD Patients.
The goal of this clinical trial is to learn if Silymarin works to reduce oxidative stress, improve pulmoary function and quality of life in stable COPD patients. It will also learn about the safety of drug Silymarin.
- Trial name
- NCT07123922
- Testing
- Silymarin
- Where
- Bangladesh
- Volunteers
- 70 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Chronic Nausea, Anxiety
AROMA-NT: Essential Oils and Wearable TENS Device for Chronic Nausea
This study will investigate how two inhaled essential oil products (QueaseEASE and STILL) and a wearable transcutaneous electrical nerve stimulation (TENS) device (ReliefBand) affect chronic nausea and anxiety in adults with…
- Trial name
- AROMA-NT (NCT07720336)
- Testing
- Inhaled Essential Oils, Wearable TENS Device
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Ohio State University
Cerebral Palsy, Sleep Disorders
Sleep Quality, Caregiver Burden, Stress, and Self-Efficacy in Parents of Children With Spastic Diplegic Cerebral Palsy: A Comparison by Night Orthosis Use
This observational study aims to compare sleep quality, caregiver burden, stress, and self-efficacy between parents of children with spastic diplegic cerebral palsy who use night orthoses and those who do not.
- Conditions
- Cerebral Palsy, Sleep Disorders, Caregiver Burden
- Trial name
- NCT07846917
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Post Traumatic Stress Disorder, Diminished Pleasure
Psychotherapy Effects on Reward Processing in PTSD
The purpose of this study is to identify how trauma-focused psychotherapy changes the function of brain circuitry in posttraumatic stress disorder (PTSD) and how this mediates improvements in the diminished ability to experience…
- Conditions
- Post Traumatic Stress Disorder, Diminished Pleasure, Anhedonia, PTSD
- Trial name
- PERPP (NCT06096740)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Texas at Austin
Chronic Obstructive Pulmonary Disease
Cardiovascular Risk and Chronic Obstructive Pulmonary Disease
The principal objective of the study is to measure parameters of inflammation, oxidative stress, and vascular, respiratory, and peripheral muscle function parameters, and identify parameters indicative of evolving cardiovascular…
- Trial name
- ECO-COPD (NCT03014609)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Stress Disorders, Post-Traumatic, Pain, Chronic
Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain
Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that efficiently target both PTSD and CP are limited, and new interventions…
- Trial name
- NCT07725588
- Testing
- Mantram Repetition Program for PTSD + Pain, Health Education while Living with Pain
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Whiplash Associated Disorder (WAD)
Transauricular Vagus Nerve Stimulation for Chronic Whiplash Associated Disorders
Approximately 50% of people with chronic whiplash-associated disorders (WAD) continue to report the presence of symptoms 12 months post-injury.
- Trial name
- NCT07055373
- Testing
- Transauricular Vagal Nerve Stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Inflamation, COPD
Inflammation and Oxidative Stress in COPD
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide, characterized by persistent airflow limitation, chronic inflammation, and increased oxidative stress.
- Conditions
- Inflamation, COPD, Oxidative Stress, Pulmonary Rehabilitation
- Trial name
- NCT07376161
- Testing
- Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Esra Yazar
Caregiver Burden, Health Literacy
Burden of Care and Health Literacy of Caregivers in the Emergency Department
This study aims to investigate the relationship between caregiver burden and health literacy among primary caregivers of patients with chronic diseases presenting to the emergency department.
- Conditions
- Caregiver Burden, Health Literacy, Chronic Disease, Emergency Service Utilization
- Trial name
- NCT07666373
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Type 1 Diabetes, T1D
DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with…
- Conditions
- Type 1 Diabetes, T1D, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- DASH-Obesity (NCT07638345)
- Testing
- Adhera Caring Digital Program-Obesity (ACDP-O)
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute