Clinical trials: Chronic TMD Pain
Temporomandibular Disorders
Shamanic Healing for Women With Temporomandibular Joint Disorders (TMDs)
This is a Phase I study to examine the feasibility and safety of shamanic (spiritual) healing for treating temporomandibular joint disorders (TMDs).
- Trial name
- NCT00071474
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
TMD/Orofacial Pain, Fibromyalgia (FM)
Diagnostic and Prognostic Salivary Biomarkers in Chronic Muscle Pain
A large proportion of the adult population worldwide currently lives with chronic muscle pain, with more than half of those affected experiencing pain localized to the face and jaw.
- Trial name
- NCT06994156
- Where
- Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders
Erenumab-aooe for Temporomandibular Disorders Management: TMD Cgrp Antibody RElief (TMD CARE)
Evaluate erenumab- aooe efficacy as a therapeutic approach, for the management of painful chronic temporomandibular disorders (TMD).
- Trial name
- TMD CARE (NCT05162027)
- Testing
- Erenumab-Aooe 70 MG in 1 mL Prefilled Syringe
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Maryland, Baltimore
Chronic TMD Pain, Temporomandibular Disorder
R01_Pilot Jaw Muscle Phenotypes
The proposed study will assess the effect of local heat therapy on jaw pain and jaw fatigue secondary to a teeth clenching task in chronic TMD pain cases.
- Trial name
- NCT07153107
- Testing
- Local Heat Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Temporomandibular Disorders
Effects of Mandibular Exercises Effect on Pain Perception and Sensitivity in Mandibular Myofascial Pain
The effectiveness of mandibular exercises as a treatment of muscular Orofacial Pain is yet unknown. This study hypothesized that training exercises can be an effective therapy improving pain perception.
- Trial name
- NCT03339739
- Testing
- Isometric mandibular exercises, Isotonic mandibular exercises, Counseling group
- Volunteers
- 45 people
- Sponsor
- Universidad Nacional Andres Bello
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Facial Pain, Temporomandibular Joint Disorder
Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic Facial Pain
This study provides a mechanism for evaluating patients for possible participation in NIDCR clinical research studies. NIDCR studies involve three major areas-pain, neurosensory mechanisms, and pain-relieving drugs-all of which…
- Trial name
- NCT00001600
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Temporomandibular Disorders
Additional Effect of Pain Neuroscience Education to Orofacial and Neck Exercises in Temporomandibular Disorders
The objective of this study will be to verify the additional effect of Pain Neuroscience Education program to orofacial manual therapy and orofacial and neck motor control exercises for pain intensity and disability and for the…
- Trial name
- NCT03926767
- Testing
- Pain Neuroscience Education (PNE), Orofacial Manual Therapy, Orofacial Exercises
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- University of Sao Paulo
Temporomandibular Disorders, Psychological Distress
How Dentists' Personality Traits Affect Communication and Treatment Outcomes in TMD Patients
This prospective, longitudinal study investigates the influence of dentists' personality traits on patient-reported outcomes among individuals with temporomandibular disorders (TMDs) undergoing splint therapy.
- Conditions
- Temporomandibular Disorders, Psychological Distress, Chronic Orofacial Pain
- Trial name
- TMD (NCT07074366)
- Testing
- Splint Therapy with Structured Communication
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Temporomandibular Disorder
K23- Physical Self Regulation vs Placebo
This study will use a between-person design. Participants will be treatment-seeking patients with chronic masticatory muscle pain.
- Trial name
- NCT06357702
- Testing
- Physical Self Regulation Telehealth, Psycho-education Telehealth
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Ian Boggero, PhD
Temporomandibular Joint Disorders, Orofacial Pain
Individualized Assessment and Treatment for TMD
Temporomandibular/orofacial pain disorders (TMD) are a group of painful conditions with multiple determinants.This proposal has two main goals: 1) to test a highly individualized, adaptive treatment for TMD that has potential to…
- Trial name
- TMD3c (NCT04376333)
- Testing
- Cognitive-Behavioral Treatment, Individualized Assessment and Treatment Program, Standard Conservative Care
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- UConn Health
TMD
Pain Neuroscience Education, Motor Imagery and Action Observation in Patients With Chronic Temporomandibular Disorders.
The objective of this study will be to verify the additional effect of Pain Neuroscience Education, Motor Imagery and Action Observation on primary outcomes pain intensity and craniofacial pain and disability in patients with…
- Trial name
- NCT05003349
- Testing
- Occlusal Splint (OS)., Pain Neuroscience Education (PNE)., Motor Imagery (MI).
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- University of Gran Rosario
Temporomandibular Disorder (TMD), Chronic Pain
Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls
Occlusal sensitivity refers to the ability to detect fine objects placed between opposing teeth during biting or in maximum intercuspation.
- Trial name
- SENFOIL (NCT07163494)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Neck Pain Musculoskeletal, Chronic Neck Pain
Effects of Neck Stabilizers Retraining on Chronic Neck Pain
The present study aims to evaluate the effects of deep neck stabilizers retraining with pressure biofeedback on cervical range of motion, pain, and temporomandibular dysfunction in patients with chronic neck pain.
- Trial name
- PBU (NCT07266610)
- Testing
- Biofeedback-assisted deep neck flexor retraining, Conventional exercises
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Temporomandibular Dysfunction (TMD)
Effect of Noninvasive Neuromodulation on Chronic Pain
1. BACKGROUND: Temporomandibular Dysfunction (TMD) is a disease characterized by a set of signs and symptoms that may include joint noise, pain in the mastication muscles, limitation of mandibular movements, facial pain, joint…
- Trial name
- NCT03285685
- Testing
- active tDCS
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Federal University of Paraíba
Myofascial Pain Syndrome, Temporomandibular Disorder
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Participants with chronic orofacial pain caused by masticatory and neck muscles will be distributed in two groups, both followed with the same occlusal and self-care treatment.
- Trial name
- TrP-TMD (NCT03619889)
- Testing
- Manual pressure release technique on trigger points.
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Complutense de Madrid
Temporomandibular Joint Disorders
Acute Effects of Alcohol Use on Chronic Orofacial Pain
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions…
- Trial name
- NCT04019093
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Florida
Neck Pain, Central Nervous System Sensitization
Central Sensitization and Clinical Parameters in Chronic Neck Pain
This study is a retrospective, cross-sectional observational study that assesses the correlations among central sensitization, pain, psychosocial factors, and temporomandibular function in patients with chronic neck pain.
- Conditions
- Neck Pain, Central Nervous System Sensitization, Temporomandibular Joint Dysfunction Syndrome, Chronic Pain
- Trial name
- NCT07462416
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Turkoglu Dr. Kemal Beyazit State Hospital
Temporomandibular Joint Disorders
Efficacy of Repetitive Transcranial Magnetic Stimulation in Temporomandibular Disorders.
Temporomandibular disorder (TMD) refers to a group of musculoskeletal conditions that affect the temporomandibular joint (TMJ), the masticatory muscles, and the associated structures.
- Trial name
- NCT06813040
- Testing
- Active rTMS
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- University of Coimbra
Neck Disability, Temporomandibular Disorders (TMD)
Neck Disability and Temporomandibular Disorders
This cross-sectional study investigates neck-related disability in individuals with chronic neck pain by examining the combined influence of temporomandibular disorders, sleep quality, and cervical sensorimotor function within a…
- Trial name
- NCT07444944
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital