Clinical trials: Chronic TMD Pain
Temporomandibular Joint Dysfunction Syndrome, Chronic Pain
Restoring Masticatory Function to Treat Chronic Pain
The primary endpoint will be the average change in pain score from baseline to the three- and six-month assessments. Efficacy will be demonstrated by superior pain relief with the active treatment compared with the placebo.
- Trial name
- MAP (NCT02144233)
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 77 people
- Sponsor
- Urbano Santana Penin, MD, DDS, PhD
Chronic Pain, Temporomandibular Joint Disorders
Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders
This study addresses the timely problem of painful temporomandibular disorders (TMD), the most common cause of orofacial pain second only to tooth pain.
- Conditions
- Chronic Pain, Temporomandibular Joint Disorders, Temporomandibular Joint Pain
- Trial name
- NCT05068908
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders, Stress Psychological
Occlusal Splint and Counseling to Temporomandibular Disorder
The aim of this study was to evaluate the effectiveness of the splint occlusal associated with counseling in reducing pain in patients with temporomandibular disorders, under the assumption that the occlusal appliance offers the…
- Conditions
- Temporomandibular Disorders, Stress Psychological, Musculoskeletal Diseases
- Trial name
- NCT01544439
- Testing
- stabilizing appliance, Non-occluding splint, counseling
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Patra-cia Rocha Coelho
Chronic Pain, Temporomandibular Disorder
An Internet-based Multimodal Pain Program for Chronic Temporomandibular Disorder Pain
Background Chronic temporomandibular disorders (TMD) pain is an undertreated condition in Sweden despite the fact that national guidelines includes effective treatment options.
- Trial name
- NCT04363762
- Testing
- Internet-based multimodal pain program, Occlusal splint
- Volunteers
- 40 people
- Sponsor
- Malmö University
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
The Effectiveness of Temporomandibular Joint Mobilization and Exercise in Individuals With Chronic Neck Pain
To examine the effects of temporomandibular joint mobilization and exercises added to the conventional physiotherapy program on posture, functionality and muscular endurance in individuals with chronic neck pain.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Neck Pain, Chronic Pain
- Trial name
- NCT06005922
- Testing
- physiotherapy, TMJ exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Uskudar University
Temporomandibular Disorders, Temporomandibular Joint Pain
Neck Exercises in Patients With Temporomandibular Disorders
Musculoskeletal (MSK) pain is a common reason to seek medical treatment. Temporomandibular disorders (TMDs) are MSK disorders that affect the masticatory muscles, the temporomandibular joint, and related structures in the neck…
- Trial name
- NCT03403998
- Testing
- Exercises
- Where
- Canada
- Volunteers
- 113 people
- Sponsor
- University of Alberta
Temporomandibular Joint Dysfunction Syndrome
Additional Effects of Therapeutic Exercises Under a Behavioral Umbrella for Chronic Temporomandibular Disorders Treatment
Temporomandibular dysfunction (TMD) It's one of the main causes of oro-facial chronic pain. The psychological aspects of patients with TMD have a huge importance, affecting their ability to manage pain and interfering with the…
- Trial name
- NCT03596606
- Testing
- Manual Treatment, Myofunctional Motor control exercises
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Maxilofacial Institute Bara Gaseni
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Primary Headache Disorders, Tension Headache
Pericranial and General Sensitivity in Patients With Primary Headache
Primary headaches such as migraine and tension type headache are among the most common neurological disorders and frequently cause significant disability and reduced quality of life.
- Conditions
- Primary Headache Disorders, Tension Headache, Tension-type Headache, Migraine
- Trial name
- HEAD-TMD (NCT07514208)
- Testing
- Pericranial Tenderness Assessment, Pressure Pain Threshold Assessment, Temporomandibular Disorder Assessment
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Disorder, Chronic Low-back Pain
Effect of Chronic Low Back Pain Treatment on Temporomandibular Disorder"
According to the information obtained from clinical studies, it has been stated that Temporomandibular Disorder (TMD) is associated with chronic low back pain (LBP). In this study, participants will be divided into two groups.
- Trial name
- NCT06343155
- Testing
- Therapeutic Group, Rocabado's Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Temporomandibular Joint Dysfunction Syndrome, Burning Mouth Syndrome
Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain
Patients with chronic masticatory muscle pain (i.e., pain greater than three months) or patients with burning mouth syndrome participate in this study.
- Trial name
- NCT00716807
- Testing
- nalbuphine plus naloxone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, San Francisco
Temporomandibular Disorder (TMD)
JIT: Effect of Pain on DT in TMD
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in…
- Trial name
- TMD (NCT06659991)
- Testing
- alcohol condition, control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Osteoarthritis
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint
This study will examine the effectiveness of injected hylan (Synvisc) for treating pain associated with osteoarthritis of the temporomandibular joint (jaw joint) and improving function of the joint.
- Trial name
- NCT00078351
- Testing
- High molecular weight hylan (Synvisc) injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Myofascial Pain, Temporomandibular Disorders
Study on the Effect of Granisetron on Myofascial Pain in the Orofacial Muscles
The aim of this study is to to investigate if local treatment with intramuscular injections of granisetron are effective in alleviating pain in patients with chronic myofascial pain in the orofacial muscles The study hypothesis…
- Trial name
- NCT02230371
- Testing
- Granisetron
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Chronic Migraine, Headache, Temporomandibular Joint Dysfunction
The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine
The aim of this clinical study to evaluate the effect of temporomandibular joint dysfunction accompanying patients with chronic migraine on pain, quality of life, sleep and functionality.
- Conditions
- Chronic Migraine, Headache, Temporomandibular Joint Dysfunction, Chronic Pain, Quality of Life
- Trial name
- NCT05381129
- Testing
- Detection of Pain, Quality of Life, Sleep and Functioning, Temporomandibular joint dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul University - Cerrahpasa
Temporomandibular Disorder, Nonspecific Chronic Neck Pain
Jaw Kinematics and Muscle Activation in Patients With Non-specific Chronic Neck Pain
Temporomandibular disorder (TMD) is a collective term for pain and dysfunction of the masticatory muscles and temporomandibular joint (TMJ).
- Conditions
- Temporomandibular Disorder, Nonspecific Chronic Neck Pain, Biomechanical Phenomena
- Trial name
- NCT04041271
- Testing
- Cervical range of motion (CROM), Pressure pain threshold (PPT), Cranial-cervical angle (CCA)
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Temporomandibular Disorder, Depression
Determination of Chronic Pain, Anxiety, Depression and Perceived Stress in Adults With Temporomandibular Disorders
The aim of the study was to asses levels and relationship of chronic pain, anxiety, depression and perceived stress in TMD patients .
- Conditions
- Temporomandibular Disorder, Depression, Anxiety, Pain
- Trial name
- NCT05183503
- Testing
- DC/TMD examination
- Where
- Poland
- Volunteers
- 219 people
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorders (TMD), Pregnancy
Evaluation of Temporomandibular Disorders During Pregnancy
This study aims to evaluate how temporomandibular disorders (TMD) - a condition affecting the jaw joint and chewing muscles - change during pregnancy.
- Trial name
- NCT07791173
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Zeynep Serra Kalkan