Clinical trials: Chronic Tinnitus
Tinnitus, Subjective
The Study of Wuling Capsule in Treatment Chronic Tinnitus
To evaluate the effect of psychological/mental factors on the severity of subjective tinnitus, to observe the efficacy and safety of Wuling capsule in the treatment of chronic subjective tinnitus with emotional disorders, and to…
- Trial name
- NCT03674853
- Testing
- Wuling Capsule, Oryzanol
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Xijing Hospital
Chronic Subjective Tinnitus
Efficacy Analysis of Transcutaneous Auricular Vagus Nerve Stimulation Combined With Tailor-Made Notched Music Therapy in the Treatment of Chronic Subjective Tinnitus
The goal of this multicenter, randomized, double-blind clinical trial is to compare two treatments for adults with chronic subjective tinnitus.
- Trial name
- NCT07794462
- Testing
- taVNS Combined With TMNMT
- Where
- 6 sites in China
- Volunteers
- 444 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus, Subjective
MRI Study of Noninvasive Transcranial Electrical Stimulation in Tinnitus
The purpose of this research is to understand how a neuromodulation technique, transcranial electrical stimulation (tES), affects brain function in adults with chronic tinnitus measured with functional magnetic resonance imaging…
- Trial name
- NCT03544359
- Testing
- Transcranial electrical stimulation (tES)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Tinnitus
The Effect of Tinnitus Retraining Therapy on Subjective and Objective Measures of Chronic Tinnitus
The objective of this study is to examine the efficacy of tinnitus retraining therapy (TRT) as a treatment of chronic tinnitus in people with limited hearing loss.
- Trial name
- NCT00124800
- Testing
- Tinnitus retraining therapy, Sound therapy
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Tinnitus Research Consortium
Tinnitus
Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus.
Tinnitus is a widespread problem that affects the quality of life of millions globally. Few treatments have been found to be effective for subjective tinnitus and to have a significant improvement on quality of life.
- Trial name
- TINNITY (NCT05300594)
- Testing
- Plant extracts, vitamins and mineral
- Where
- France
- Volunteers
- 110 people
- Sponsor
- CEN Biotech
Chronic Insomnia, Chronic Pain
Lemborexant vs Clonidine vs Sedatives to Treat Insomnia in Chronic Pain Patients
Prospective observational crossover study of 250 adults undergoing chronic pain management. For insomnia treatment, patients alternate their usual prescribed sedative versus Lemborexant or Clonidine; on alternate nights.
- Conditions
- Chronic Insomnia, Chronic Pain, Restless Leg Syndrome (RLS), Substance Abuse
- Trial name
- NCT05618002
- Testing
- Lemborexant
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Salem Anaesthesia Pain Clinic
Chronic Tinnitus
Conventional Repetitive Transcranial Magnetic Stimulation for Tinnitus Treatment
The objective of the investigators study is to assess conventional repetitive transcranial magnetic stimulation (rTMS) in patients with chronic severe tinnitus.
- Trial name
- MagTIN (NCT01407133)
- Testing
- transcranial magnetic stimulator (class 2b) Medtronic © MagPro X100 (with MagOption) stimulator and Butterfly Coil MCF-B65 (figure-8 coil with fluid cooling)
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Tinnitus
Comparison of an Internet-based Guided Self-help and a Group Therapy for Chronic Tinnitus
The aim of this study is to compare the efficacy of an internet-based guided self-help training for chronic tinnitus with a well-established outpatient group therapy and a discussion forum group.
- Trial name
- MINT (NCT01205906)
- Testing
- Internet-based guided self-help for tinnitus, Cognitive-behavior group therapy for tinnitus, Internet discussion forum
- Where
- Germany
- Volunteers
- 128 people
- Sponsor
- Johannes Gutenberg University Mainz
Ear Noise, Tinnitus, Noise Induced
Multimodal Therapy for Somatosensory Tinnitus
Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of the adult population and significantly reduces quality of life in many patients.
- Conditions
- Ear Noise, Tinnitus, Noise Induced, Tinnitus, Subjective, Headache Other
- Trial name
- SOMATIN (NCT07468318)
- Testing
- Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Meniere Disease, Ménière
SPI-1005 for the Treatment of Meniere's Disease
The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three…
- Trial name
- STOPMD-3 (NCT04677972)
- Testing
- Ebselen
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Tinnitus, Subjective
ICCAC-ToNF & Tinnitus
Prevalence of chronic subjective tinnitus is rising with age and associated with maladaptive oscillatory changes in auditory as well as non-auditory regions of the brain such as the insula and the anterior cingulate cortex which…
- Trial name
- ICCAC (NCT03895047)
- Testing
- tomographic EEG Neurofeedback Training
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Tinnitus
Pilot Study of Deep Brain Stimulation (DBS) in Area LC for Chronic Tinnitus
This study will test the safety and effectiveness of deep brain stimulation (DBS) for patients with a big or very big problem with tinnitus (a sensation of noise in the head).
- Trial name
- NCT01988688
- Testing
- Deep Brain Stimulation (DBS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Paul Larson
Tinnitus, Subjective, Tinnitus, Bilateral
Tinnitus Patient Preferences Survey
The goal of this survey is to assess several aspects related to patient preferences regarding interventions for alleviating tinnitus through invasive electrical brain stimulation (neuromodulation).
- Conditions
- Tinnitus, Subjective, Tinnitus, Bilateral, Tinnitus, Noise Induced, Tinnitus, Hearing Loss, Cochlear Implant Users
- Trial name
- NCT06782308
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Nicolas Gninenko
Tinnitus
Psychophysiological Treatment of Chronic Tinnitus
The study aims to develop and to evaluate a psychophysiological intervention for distressing chronic tinnitus. Therefore 100 people suffering from chronic tinnitus are randomly assigned to either an intervention-group, receiving…
- Trial name
- NCT00397007
- Testing
- Biofeedback-based cognitive-behavioural intervention
- Where
- Germany
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Chronic Tinnitus
Combined Transcranial and Peripheral Muscle Magnetic Stimulation in Chronic Tinnitus
Magnetic stimulation of the brain (repetitive transcranial magnetic stimulation) and of neck muscles (repetitive peripheral muscle stimulation) is used to alter tinnitus-related cortical activity and neck muscles tension.
- Trial name
- rpms-tinn (NCT02306447)
- Testing
- rPMS and rTMS
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- University of Regensburg
Tinnitus
Acoustic Coordinated Reset (CR®) Neuromodulation for the Treatment of Chronic Tonal Tinnitus ("RESET Real Life")
Confirmation of efficacy and safety of acoustic CR®-neuromodulation for the treatment of chronic tinnitus patients using the CE marked ANM T30 CR®-system in a real life outpatient setting.
- Trial name
- RRL (NCT01435317)
- Testing
- ANM T30 CR®-System
- Where
- 23 sites in Germany
- Volunteers
- 200 people
- Sponsor
- ANM Adaptive Neuromodulation GmbH
Tinnitus, Subjective
HD-tDCS as a Treatment for Chronic Tinnitus
Transcranial Direct Current Stimulation (tDCS) aims to induce cortical plasticity by modulating the activity of brain structures.
- Trial name
- NCT04565132
- Testing
- High Definition transcranial Direct Current Stimulation
- Volunteers
- 117 people
- Sponsor
- University Hospital, Antwerp
Chronic Tinnitus
Mindfulness-based Therapy in Chronic Tinnitus
In the present randomized waiting-list-controlled study the investigators examined a specific manualized mindfulness-based therapeutic approach in the treatment of chronic tinnitus.
- Trial name
- NCT01540357
- Testing
- Mindfulness-based therapy, Treatment after waiting time
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Regensburg
Tinnitus
Internet-based Guided Self-help for Chronic Tinnitus
The purpose of this study is to determine the efficacy of a cognitive behavioral guided self-help training provided via the internet on tinnitus distress in a German sample.
- Trial name
- TITUS (NCT01205919)
- Testing
- Internet-based guided self-help for tinnitus, Internet discussion forum
- Where
- Sweden
- Volunteers
- 124 people
- Sponsor
- Johannes Gutenberg University Mainz
Tinnitus
Tinnitus Sound Therapy Using Mobile Application.
Over the years Tinnitus Sound Therapy (TST) has been undergoing rigorous modification according to the availability of various technologies such as Hearing Aids, personal amplification devices, mp3 players, and now mobile phones.
- Trial name
- TST (NCT06104865)
- Testing
- Tinnitus Sound Therapy using (Resound Tinnitus relief) mobile application
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Basel Samman