Clinical trials: Chronic Tinnitus
Tinnitus
Neuro-Music-Therapy for Patients With Chronic Tinnitus - a Controlled Clinical Trial
BACKGROUND: Tinnitus is a nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear.
- Trial name
- NCT01845155
- Testing
- Neuro-Music-Therapy according to the Heidelberg Model, Counselling
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- German Center for Music Therapy Research
Tinnitus, Bilateral, Cochlear Synaptopathy
A Study Testing Safety and Efficacy of Transtympanic Paliroden for the Treatment of Cochlear Synaptopathy in Participants With Chronic, Constant Tinnitus
The goal of this clinical trial is to investigate if paliroden (CIL001) is safe and can help treat cochlear synaptopathy in adult participants 18-75 years of age with normal hearing thresholds and normal cognition who exhibit…
- Trial name
- REACT (NCT07826507)
- Testing
- paliroden (CIL001)
- Volunteers
- 60 people
- Sponsor
- Cilcare SAS
Hearing Disorders, Hearing Loss
Chronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus
The purpose of this study is to determine whether chronic electrical stimulation of the primary auditory cortex is effective in the treatment of chronic, severe and intractable tinnitus
- Conditions
- Hearing Disorders, Hearing Loss, Hyperacusis, Tinnitus
- Trial name
- ACOUSCO (NCT00486577)
- Testing
- significant chronic primary auditory cortex stimulation during the first two weeks, non significant chronic primary auditory cortex stimulation during the first two weeks
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Bordeaux
Tinnitus
Novel Tinnitus Implant System for the Treatment of Chronic Severe Tinnitus
Researchers are gathering information on the safety and effectiveness of a novel device called the Tinnitus Implant System for the treatment of tinnitus.
- Trial name
- NCT03988699
- Testing
- Tinnitus Implant System
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Matthew L. Carlson, M.D.
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Tinnitus, Subjective
Consecutive Dual-Session tDCS in Chronic Subjective Severe to Catastrophic Tinnitus With Normal Hearing
We aimed to analyze the effect of continuous dual session tDCS in patients with severe chronic subjective tinnitus without any evidence of hearing loss in terms of relief of tinnitus perception, distress, and loudness.
- Trial name
- NCT06423742
- Testing
- Transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Dongtan Sacred Heart Hospital
Tinnitus, Subjective
Sulodexide Efficacy in Chronic Idiopathic Subjective Tinnitus
The objective of this prospective randomized and double blind controlled study is to evaluate the efficacy and safety of Sulodexide (25 mg) in the treatment of chronic idiopathic subjective tinnitus.
- Trial name
- SECIST (NCT02737670)
- Testing
- Sulodexide
- Where
- Lebanon
- Volunteers
- 126 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Tinnitus, Subjective
Repetitive Transcranial Magnetic Stimulation for Chronic Subjective Tinnitus
Therapy of subjective chronic primary tinnitus could be challenging. Repetitive transcranial magnetic stimulation (rTMS) is currently being tested for suppressing the symptoms.
- Trial name
- NCT03425045
- Testing
- Repetitive Transcranial Magnetic Stimulation, Ginkgo Biloba Extract
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital Ostrava
Tinnitus, Subjective
Efficacy Study for Development and Use of Neurofeedback-trainings for Patients Suffering From Chronic Tinnitus
Chronic tinnitus affects about 10-15% of the population in industrialized countries. Investigations of the brain activity by using electroencephalography (EEG) showed that in localized regions of the hearing system brain activity…
- Trial name
- NCT02383147
- Testing
- Tomographic Neurofeedback, Non Tomographic Neurofeedback
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University of Zurich
Tinnitus
The Effect of Gabapentin on the Sensation and Impact of Tinnitus
This study evaluated the effectiveness of gabapentin in treating tinnitus in two populations: Tinnitus with associated acoustic trauma and tinnitus without associated acoustic trauma.
- Trial name
- NCT00257270
- Testing
- gabapentin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tinnitus Research Consortium
Tinnitus, Hearing Loss
Neuromodulation Techniques in the Treatment of Chronic Tinnitus With Hearing Loss
This study aimed at trying transcranial magnetic stimulation and transcranial direct current stimulation as potential treatments to decrease tinnitus in patients with significant hearing loss.
- Trial name
- NCT01944501
- Testing
- Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Brasilia
Tinnitus, Chronic Subjective Tinnitus
Acute Nicotine Gum and Auditory Brain Responses in Adults With Chronic Tinnitus
This study tests whether a single dose of nicotine gum changes brain responses to sounds and the ability to detect target sounds in non-smoking adults with chronic tinnitus.
- Trial name
- NCT07877701
- Testing
- Nicotine polacrilex gum 4 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Xianhui Wang
Chronic Tinnitus
Hearing Aid Impact on Chronic Tinnitus Patients Evaluated by Resting State PET.
Using resting state positron emission tomography (PET), our goal was to analyze the metabolic and functional neural changes that occur after 6 months of effective hearing aid (HA) use.
- Trial name
- NCT03657615
- Testing
- hearing aid fitting
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Tinnitus
Treatment of Chronic Bothersome Tinnitus Using Cognitive Training and D-cycloserine
The purpose of this research study is to determine if a medication along with a computer program designed to improve memory and other mental processes can help people like yourself with tinnitus.
- Trial name
- NCT01550796
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Washington University School of Medicine
Tinnitus
A Comparison of the Benefits of Mindfulness Based Cognitive Therapy, Relaxation Therapy and a Waiting List Control in the Management of Distress in Chronic Tinnitus Patients
The principal hypotheses to be tested is that Mindfulness Based Cognitive Therapy (MBCT) reduces the distressing impact of tinnitus to a significantly greater extent than a waiting list control or relaxation therapy.
- Trial name
- NCT02059447
- Testing
- No treatment waiting period, Mindfulness Based Cognitive Therapy, Relaxation Therapy
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University College London Hospitals
Tinnitus, Trigger Point Pain, Myofascial
Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study
Self paring study, double blind placebo controlled with chronic tinnitus patients attended at the Tinnitus Research Group HC- FMUSP, complaining of neck and/or cervical pain and with myofascial trigger point in the head, neck…
- Conditions
- Tinnitus, Trigger Point Pain, Myofascial, Somatosensory Disorders
- Trial name
- NCT03295890
- Testing
- Dry Needing
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Tinnitus
A Study on the Effect of Cilostazol in Patients With Chronic Tinnitus
1. Overview of tinnitus Tinnitus is a noisy sound which is perceived without any external sound source. According to the survey of the US, 10-20% of adult have the symptom of tinnitus and 3-5% of tinnitus patients have severe…
- Trial name
- CITI-ESR (NCT01378650)
- Testing
- Cilostazol
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Jong Woo Chung
Tinnitus
Personalized Music-Embedded Sound Therapy Based on Gating Modulation and Neural Decoupling Reduces Tinnitus Severity
This clinical trial evaluated a personalized music-embedded sound therapy for adults with chronic subjective tinnitus. Tinnitus is the perception of sound, such as ringing or buzzing, without an external source and can negatively…
- Trial name
- NCT07637708
- Testing
- Music intervention
- Where
- Chile
- Volunteers
- 25 people
- Sponsor
- University of Chile
Chronic Tinnitus
Short-term Effects of Oxytocin Nasal Spray on Chronic Tinnitus
The study compares the short-term tinnitus reduction following a single oxytocin intervention with a placebo control condition.
- Trial name
- NCT02508220
- Testing
- Syntocinon
- Volunteers
- 15 people
- Sponsor
- Berthold Langguth, MD, Ph.D.
Tinnitus, Pain
Modulating Mechanisms in Patients With Chronic Subjective Tinnitus and/or Chronic Pain
This is a cross-sectional investigation into modulating mechanisms in patients with chronic subjective tinnitus, which will compare 4 patient groups namely chronic tinnitus with chronic pain, chronic tinnitus without chronic…
- Trial name
- NCT05186259
- Testing
- Self-reported signs of central sensitization, Objective signs of central sensitization, Audiological outcome measures (audiometry, tinnitus analysis, uncomfortable loudness) in tinnitus patients with and without pain
- Where
- Belgium
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Ghent