Clinical trials: Chronic UTI
Urinary Retention, Neurogenic Bladder
Connected Catheter- Safety and Effectiveness Study
The Connected Catheter is a fully internal, urethral indwelling urinary prosthesis designed for improved bladder management in males with urinary retention disorders requiring catheterization.
- Conditions
- Urinary Retention, Neurogenic Bladder, Urologic Diseases
- Trial name
- NCT03843073
- Testing
- Connected Urinary Catheter
- Where
- 9 sites in United States
- Volunteers
- 9 people
- Sponsor
- Spinal Singularity
Urinary Tract Infections in Children, Dexamethasone
Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Children
Urinary tract infection (UTI) is the most frequently occurring serious bacterial infection in young children and accounts 5 to 14% of emergency department visits Formation of renal scarring in children has been associated with…
- Conditions
- Urinary Tract Infections in Children, Dexamethasone, Kidney Scarring, Acute Pyelonephritis
- Trial name
- NCT04654507
- Testing
- Dexamethasone Oral
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Urologic Diseases, Urinary Tract Infections
Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients
This is a single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa care (Komplexní lázeňská léčebně rehabilitační péče, KLP) on patients with nephrological and urological conditions treated at a spa…
- Conditions
- Urologic Diseases, Urinary Tract Infections, Nephrolithiasis, Nephrocalcinosis
- Trial name
- Uro-Nefro (NCT07435844)
- Testing
- Comprehensive Spa Care, Exercise Therapy, Dietotherapy
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Recurrent Urinary Tract Infections, Chronic Urinary-catheter-carrier
Comparison of Three Different Antibiotic Treatments Against Recurrent Urinary Tract Infections in Catheterized Patients
Recurrent urinary tract infections (UTI) in the patients chronically catheterized are serious challenges clinically. The pathogens are often multidrug-resistant bacteria and such UTIs are actually biofilm infections.
- Conditions
- Recurrent Urinary Tract Infections, Chronic Urinary-catheter-carrier, Biofilm Infection, Antibiotic Treatment
- Trial name
- NCT05402319
- Testing
- Antibiotic combination therapy
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Inflammation on Dialysis, Bacteriuria in Hemodialysis Patients
Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients
When considering occult infections during the diagnostic workup of inflammation in Hemodialysis (HD) patients, the urine-deprived bladder is frequently dismissed as potential site of infection.
- Trial name
- NCT01570556
- Testing
- Antibiotic treatment
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Assaf-Harofeh Medical Center
Neurogenic Bladder, Spinal Cord Injuries
Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections
Participants will undergo daily gentamicin bladder instillations to determine if its use will reduce the rate of symptomatic urinary tract infections (UTIs) as well as the use of oral and intravenous antibiotics in adults with…
- Trial name
- NCT03931408
- Testing
- Gentamicin Sulfate, No instillation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Chronic Diseases
Urinary Catheter Self-care Management
It is important for healthcare professionals to be sensitive to the needs of patients undergoing urinary catheterization. Patients and their relatives should be educated, guided and supported by nurses and other healthcare…
- Trial name
- NCT06179238
- Testing
- Education, without patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kastamonu University
Patients with Recurrent or Chronic UTIs, Patients with a Suprapubic Catheter
Analysis of Bacterial Multidrug Tolerance in Patients Prone to Urinary Tract Infections
Prospective observational study aimed at collecting bacterial isolates from patients with recurrent or chronic UTIs, or patients with suprapubic or nephrostomy catheters.
- Conditions
- Patients with Recurrent or Chronic UTIs, Patients with a Suprapubic Catheter, Patients with a Nephrostomy Catheter
- Trial name
- NCT06724588
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Natalie Verstraeten
Urinary Tract Infections, Chronic Urinary Tract Infection
Expanded Access Program Using Uromune for Patients With Recurrent Urinary Tract Infections (rUTI)
An Expanded Access Program for UROMUNE® for patients suffering from recurrent/chronic urinary tract infections of diverse etiology.
- Conditions
- Urinary Tract Infections, Chronic Urinary Tract Infection, Recurrent Urinary Tract Infection, Urinary Tract Infection Bacterial
- Trial name
- NCT04173013
- Testing
- Uromune
- Where
- 15 sites in Belgium, Czechia and 13 more
- Sponsor
- Impatients N.V. trading as myTomorrows
Recurrent UTIs, Recurrent Urinary Tract Infections
A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections
A randomized, double-blind, placebo-controlled, 12-month study to determine the effectiveness of D-mannose (2g daily) supplementation in rUTI (recurrent urinary tract infection) prevention in post-menopausal women.
- Conditions
- Recurrent UTIs, Recurrent Urinary Tract Infections, Recurrent Urinary Tract Infections in Women, Recurrent Urinary Tract Infection
- Trial name
- DmannoseRCT (NCT06940622)
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas Southwestern Medical Center
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Renal Insufficiency
Association Between COVID-19 and UTIs Caused by ESBL Organism in Infants
Urinary tract infections (UTIs) in infants and young children are one of the most common bacterial infections, usually febrile illness without source, frequently due to Enterobacteriaceae, mainly Escherichia coli.
- Trial name
- ABCUCEOI (NCT05630326)
- Testing
- comparing, prevalence, assessment, association
- Where
- Qatar
- Volunteers
- 5,600 people
- Sponsor
- Hamad Medical Corporation
Dementia, Depression
Vegetarian Diet and Chronic Degenerative Diseases
To investigate the prospective association between a vegetarian diet and chronic degenerative diseases in two cohorts of Taiwanese Buddhists
- Conditions
- Dementia, Depression, Cardiovascular Diseases, Stroke
- Trial name
- NCT03470584
- Testing
- Diet Exposure
- Where
- Taiwan
- Volunteers
- 18,064 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Urologic Diseases, Patient Satisfaction
Developing a PROM for Recurrent Urinary Tract Infection
This study aims to develop and validate the first set of patient-reported outcome measures for recurrent urinary tract infection (UTI): the Recurrent UTI Symptom Scale and the Recurrent UTI Impact Questionnaire.
- Conditions
- Urologic Diseases, Patient Satisfaction, Pain, Chronic, Sexual Dysfunction
- Trial name
- NCT05086900
- Testing
- Non-interventional Cross-sectional Patient Reported Outcome Measure Development
- Where
- United Kingdom
- Volunteers
- 283 people
- Sponsor
- University of Reading
Urinary Retention, Chronic Kidney Infection
Comparison of Two Bladder Catheterization Strategies in Thoracic Surgery Patients With an Enhanced Recovery After Surgery (ERAS)
General anesthesia, thoracic epidural, and morphine inhibit the urination process and promote postoperative Acute Urinary Retention (AUR) after thoracic surgery.
- Conditions
- Urinary Retention, Chronic Kidney Infection, Urinary Infection
- Trial name
- URICATHOR (NCT05611255)
- Testing
- Systematic Intermittent Catheterization, Bladder Scan Guided Catheterization
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier
UTI, Neurogenic Bladder
Preventing UTIs in Chronic Neurogenic Bladder Dysfunction (Mix Methods)
Due to the damage caused to the spinal cord, patients with spinal cord injury, cauda equina syndrome, multiple sclerosis and transverse myelitis may encounter loss of bladder function, which in turn can lead to a debilitating and…
- Conditions
- UTI, Neurogenic Bladder, Antibiotic Resistance
- Trial name
- PReSuTINeB (NCT02591901)
- Testing
- Uro vaxom
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Buckinghamshire Healthcare NHS Trust
Falls Injury, Falls
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness
Every country in the world is experiencing growth in both the size and the proportion of older persons. As a result of the changes, the profile and needs of people with medical illnesses have evolved.
- Conditions
- Falls Injury, Falls, Hospitalization in Acute Care, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT07536035
- Where
- Singapore
- Volunteers
- 220 people
- Sponsor
- National University Hospital, Singapore
Urinary Tract Infections, Chronic Kidney Diseases
Urinary Tract Infection in Patients With Chronic Kidney Disease
This study aims to investigate the etiology and associated risk factors for UTI in Egyptian chronic kidney disease patients. In addition, to identify the isolated micro-organisms and their sensitivity patterns for better…
- Trial name
- NCT05674942
- Testing
- Patients with urinary tract infection and chronic kidney disease
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Alexandria University