Clinical trials: Chronic Widespread Pain
Chronic Widespread Pain, Sleep Disturbance
Sleep Disturbances and Chronic Widespread Pain
Chronic widespread pain (CWP), defined as long-lasting pain in multiple body regions, has a prevalence of 10-14% in Europe and is associated with other physical symptoms such as fatigue and cognitive problems.
- Trial name
- POSEIDON (NCT03908905)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Knee Osteoarthritis, Widespread Chronic Pain
Prevalence and Characteristics of Widespread Pain in People With Knee Osteoarthritis
The goal is to evaluate whether the number of pain sites or pain estimation with Instant and Constant Osteoarthritis Pain (ICOAP) is related to functional impairment in the lower extremity in people with knee osteoarthritis…
- Trial name
- NCT06854237
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Vastra Gotaland Region
Mast Cell Activation Syndrome, Mast Cell Activation Disorder Idiopathic
Safety and Efficacy of FSD201 for the Treatment of Chronic Pain Associated With Idiopathic MCAS (MCAD)
This study will determine if FSD201 reduces the average daily 24-hour recall pain intensity after 28 and 56 days of treatment in adults with chronic widespread musculoskeletal nociplastic pain.
- Trial name
- NCT05652907
- Testing
- FSD201
- Where
- 3 sites in United States, Canada
- Volunteers
- 2 people
- Sponsor
- Quantum Biopharma
Chronic Widespread Pain, Fibromyalgia
Body Versus Machine: Deep Breathing Versus Vagus Stimulation for the Treatment of Fibromyalgia
This randomized controlled trial aims to compare the efficacy of two vagal nerve innervation treatments, motivational nondirective resonance breathing and transcutaneous vagus nerve stimulation, on heart rate variability and pain…
- Trial name
- NCT03180554
- Testing
- Transcutaneous Vagal Nerve Stimulation (tVNS), Motivational nondirective resonance breathing (MNRB)
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Charles Ethan Paccione, M.S., M.A.
Anxiety Disorder, Chronic Myeloproliferative Disorders
Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation
RATIONALE: Music therapy may be effective in relieving pain and emotional distress in patients who are undergoing cancer therapy.
- Conditions
- Anxiety Disorder, Chronic Myeloproliferative Disorders, Depression, Lymphoma
- Trial name
- NCT00014482
- Testing
- pain therapy, psychosocial assessment and care
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pain, Chronic Widespread Pain
Enhancing Analgesia in Chronic Pain Through Exercise
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies.
- Conditions
- Pain, Chronic Widespread Pain, Fibromyalgia
- Trial name
- NCT04862871
- Testing
- Physical Activity - Pediatric Pain Rehabilitation Center
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Chronic Pain
DNIC Using Deep Learning and Artificial Intelligence
Chronic pain (CP) is disabling for people triggering important costs for society. A deficit of diffuse noxious inhibitory controls (DNIC) is one of the CP mechanisms.
- Trial name
- NCT04896827
- Testing
- Conditioned pain modulation test
- Where
- Canada
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Fibromyalgia, Chronic Widespread Pain
Mindfulness Interventions and Chronic Widespread Pain in Adolescents
The primary objective of this study to determine the feasibility and acceptability of a mindfulness intervention for adolescents with juvenile fibromyalgia/ chronic widespread pain and other similar chronic symptoms.
- Trial name
- NCT02190474
- Testing
- Mindfulness Group
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Yale University
Chronic Pain, Chronic Pain Syndrome
Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain
This study will evaluate a new form of non-invasive deep brain therapy for individuals with generalized chronic pain. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation…
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Widespread Chronic Pain
- Trial name
- DBT (NCT05674903)
- Testing
- Verum stimulation with Diadem prototype
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Chronic Pain, Pain
Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"
Chronic pain is a significant public health problem that affects over 116 million Americans, costs $600 billion annually, and is unequally borne by people in low-income brackets, especially ethnic minorities.
- Conditions
- Chronic Pain, Pain, Widespread Chronic Pain, Chronic Pain Syndrome
- Trial name
- LAMP (NCT01967342)
- Testing
- Pain Ed, CBT for Pain, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- University of Alabama, Tuscaloosa
Fibromyalgia, Pain
Men With Fibromyalgia or Chronic Widespread Pain - Effect of Exercise on Symptoms and Body Functions
A controlled randomised trial (CRT). 60 men who fulfil the ACR-criteria for Fibromyalgia or Chronic Widespread Pain (Wolfe 1990) participate in the study.
- Trial name
- NCT01278641
- Testing
- Graded strength resistance training program, Temperate pool exercise program
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Göteborg University
Anxiety Disorder, Cancer Survivor
Quality of Life in Younger Leukemia and Lymphoma Survivors
RATIONALE: Collecting information about the effect of hematologic cancer and its treatment on quality of life may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Anxiety Disorder, Cancer Survivor, Fatigue, Leukemia
- Trial name
- NCT00956475
- Testing
- telephone-based intervention, questionnaire administration, assessment of therapy complications
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Case Comprehensive Cancer Center
Widespread Chronic Pain
The Maintaining Musculoskeletal Health Study
It is known from many studies that when patients have developed chronic widespread pain (CWP) or fibromyalgia that managing such symptoms is extremely challenging for both doctors and patients.
- Trial name
- MAmMOTH (NCT02668003)
- Testing
- Cognitive Behavioural Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Widspread Chronic Pain, Fibromyalgia
The Effect of Vagus Nerve Stimulation on Pain and Functional Activities in Individuals With Chronic Widespread Pain
The goal of this clinical trial is to examine the effect of vagus nerve stimulation (VNS) on chronic, widespread pain in adults.
- Trial name
- NCT07080749
- Testing
- Vagal nerve stimulation through deep exhalation exercise, Vagal nerve stimulation through ear electrical stimulation, No intervention (observational study)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Georgia
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Chronic Widespread Pain, Fibromyalgia (FM)
The Added Value of Transcranial Direct Current Stimulation (tDCS) During Exercise for People With Chronic Widespread Pain
Many people with chronic widespread pain (CWP) feel more pain and fatigue after exercise. This makes it hard to stay active. Unfortunately, the investigators do not fully understand why this happens and how to prevent it.
- Trial name
- NCT07212829
- Testing
- Active tDCS, Aerobic exercise
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Widespread Pain
The Role of Epigenetic Mechanisms in Stress Intolerance in Patients With Chronic Widespread Pain
Patients with chronic widespread pain (CWP) frequently experience stress intolerance - an exacerbation of symptoms in response to stress. Although it severely affects their quality of life, stress intolerance remains a mystery.
- Trial name
- EPISIP (NCT06475859)
- Testing
- Montreal Imaging Stress Test, Relaxation breathing
- Where
- Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Pain, Chronic
Group intEgrative MINdfulness Over the Internet Using an Online Platform
This is a one-year study designed to improve upon the latest version of an education website for adult chronic pain patients called Our Whole Lives for Chronic Pain (OWL-CP).
- Trial name
- GEMINI (NCT04340739)
- Testing
- online patient education teach mindfulness based stress reduction
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Massachusetts, Worcester
Fibromyalgia
Influence of Transcranial Direct Current Stimulation of the Primary Motor Cortex on Pain Sensation in Patients Suffering From Fibromyalgia Syndrome
Fibromyalgia is a common chronic pain syndrome characterized by bad treatable chronic widespread pain present at a similar level for at least 3 months.
- Trial name
- NCT01261650
- Testing
- transcranial direct current stimulation
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Karl Landsteiner Institute of Remobilization and Functional Health