Clinical trials: Chronic Wounds
Venous Leg Ulcer, Bacterial Infections
Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular Ulcers
This study will determine the effectiveness of CUTIMED® hydrophobic dressings against AQUACEL® silver dressings in bacterial colonization of vascular ulcers.
- Conditions
- Venous Leg Ulcer, Bacterial Infections, Chronic Ulcer of Skin of Lower Limb Nos
- Trial name
- CUCO-UV (NCT03667937)
- Testing
- CUTIMED, AQUACEL silver
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- University of Malaga
Tendinopathy
Shock Wave Therapy for Sural Myofascial Pain Associated to Chronic Heel Pain
The aim of this randomized controlled study in to investigate if a shock wave treatment extended to the gastrocnemius-soleus trigger points (TrP) is more effective than a standard treatment exclusively targeted at the plantar…
- Trial name
- NCT04385329
- Testing
- Shock wave therapy on plantar fascia extended to the gastrocnemius-soleus trigger points, Shock wave therapy on plantar fascia only
- Volunteers
- 55 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Evaluate the Efficacy of Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Wounds
Cyclical Topical Wound Oxygen Therapy (TWO2) in the Treatment of Chronic Wounds
To evaluate the efficacy and clinical satisfaction of topical oxygen therapy (LOT) in chronic wounds (including patients and medical staff), and explore its possible mechanism.
- Trial name
- NCT04168905
- Testing
- AOTI Inc. TWO2 topical oxygen therapy equipment
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Palsy, Osteoporosis
Influence of Verticalization on Bone Mineral Density and Biological Parameters of Bone Remodeling in Children With Severe Cerebral Palsy
Low bone mineral density affects 77% of children with severe cerebral palsy (GMFCS IV \& V) with an increased fracture risk of 4%. One strategy supposed to improve bone mineral density is verticalisation with static devices.
- Conditions
- Cerebral Palsy, Osteoporosis, Bone Mineral Density, Bone Remodeling Disorder
- Trial name
- CPABONE (NCT04761666)
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Varicose Ulcer
Preliminary Testing of New Treatment for Chronic Leg Wounds
Most chronic (long-lasting) wounds of the leg (also known as venous ulcers) fail to heal in a reasonable period of time. Although researchers have made great progress in understanding how the body repairs wounds, attempts to…
- Trial name
- NCT00000431
- Testing
- PDGF-B/Ad5
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pennsylvania
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Symptomatic Neuroma, Morton's Neuroma
Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Comparing safety, pain, user experience, healthcare economic costs, work productivity, impairment and quality of life outcomes between Axoguard® Nerve Cap and neurectomy in the treatment of symptomatic neuromas in the foot or…
- Conditions
- Symptomatic Neuroma, Morton's Neuroma, Chronic Nerve Pain
- Trial name
- REPOSE (NCT03940963)
- Testing
- AxoGuard® Nerve Cap, Standard Neurectomy
- Where
- 11 sites in United States
- Volunteers
- 86 people
- Sponsor
- Axogen Corporation
Cerebral Palsy, Hip Dislocation
GUIDed Growth of the Proximal Femur to Prevent Further Hip MigrAtion in CErebral Palsy Patients
In recent literature, the potential of guided growth of the proximal femur to modify hip growth in patients with cerebral palsy has been shown.
- Trial name
- GUIDANCE (NCT06118736)
- Testing
- Temporary Medial Hemi-epiphysiodesis of the proximal femur
- Where
- 5 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Erasmus Medical Center
Knee Injuries and Disorders, Hip Injuries and Disorders
Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery
The purpose of this study is to evaluate the use of post-operative opioid use after two different educational interventions. The investigators will compare changes in pain, disability and sleep between groups 6 months after…
- Conditions
- Knee Injuries and Disorders, Hip Injuries and Disorders, Opiate Addiction
- Trial name
- OpiateLEO (NCT02997644)
- Testing
- Video Education, Usual Care Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Epicondylitis of the Elbow, Servical Segmental Mobilization
Results of Cervical Segmental Mobilization in Patients With Chronic Lateral Epicondylitis
The aim of our study was to investigate the effect of cervical segmental mobilization on pain, functionality, grip strength and quality of life in patients with chronic lateral epicondylitis.
- Trial name
- NCT06440928
- Testing
- mobilization, standard treatment, deep friction
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Halic University
Post-Concussion Syndrome, COVID Long-Haul
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Stimulation (a Neurostim device) on children with pain and Post Concussion symptoms.
- Conditions
- Post-Concussion Syndrome, COVID Long-Haul, COVID-19
- Trial name
- NCT04978571
- Testing
- percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Children's Hospital of Orange County
Spinal Cord Injuries, Spinal Cord Diseases
Non-Invasive Electrical and Magnetic Neuromodulation in Persons With Chronic Spinal
The objectives of this study are to (1) determine the effects of neuromodulation techniques on mobility in persons with chronic SCI, as measured by subjective and objective measures, and (2) to determine the optimal combination…
- Trial name
- RISES-T2 (NCT05994846)
- Testing
- RISES-T System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Thomas Jefferson University
Chronic Pain
Peculiarities of Pain in Patients With Mine-explosive Wounds Depending on the Localization of the Wound at the Stages of Treatment
Mine-explosive wounds in the general structure of combat sanitary losses reach 25%. They are characterized by significant damage resulting in high intensity pain.
- Trial name
- PPPM-EWDL (NCT05485285)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 660 people
- Sponsor
- Bogomolets National Medical University
Traumatic Brain Injury
Executive Function Training Intervention for Chronic Traumatic Brain Injury
Traumatic Brain Injury (TBI) is a prevalent disorder developed by military personnel. While some individuals recover function within months after injury, others continue to suffer from cognitive problems months to years later and…
- Trial name
- NCT03704116
- Testing
- Expedition
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The University of Texas at Dallas
Disorder of Consciousness, Minimally Conscious State
Temporal Interference Stimulation for Disorders of Consciousness
This study aims to investigate whether a new non-invasive brain stimulation technique, called temporal interference stimulation, can influence brain activity and potentially improve signs of consciousness in patients with severe…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, Vegetative State, Unresponsive Wakefulness Syndrome
- Trial name
- NCT07874178
- Testing
- Temporal Interference
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Spinal Cord Injury, Chronic Pressure Ulcers
Subcutaneous Injection and Ultrasonic Dispersion of Cefazolin Into Chronic Pelvic-Region Pressure Ulcers in Persons With Spinal Cord Injury
Pressure ulcers (PU) are skin breakdowns that often form after blood flow in the skin is reduced from prolonged and repeated exposure to externally applied forces.
- Trial name
- NCT02584426
- Testing
- Ultrasonic Distribution of Cefazolin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Aging, Walking, Difficulty
Chronic Wounds and Blood Circulation Detection
Lower limb circulatory insufficiency and the associated chronic wounds are common health problems among the elderly. These issues not only affect the individual's mobility and quality of life but also potentially increase medical…
- Conditions
- Aging, Walking, Difficulty, Chronic Limb-Threatening Ischemia, Chronic Disease
- Trial name
- NCT07330635
- Testing
- Intervention 1: Mixed exercise program, Intervention 2: High-intensity rowing exercise, Intervention 3: Vibration exercise
- Where
- Taiwan
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Diabetes Mellitus, Biomarker
Study of Biomarkers in Diabetic Chronic Wounds
This study aims to discover, verify and evaluate the potential biomarkers with regard to the diagnosis, prognostic and/or prediction of diabetic chronic wounds.
- Conditions
- Diabetes Mellitus, Biomarker, Chronic Wound
- Trial name
- NCT05342740
- Testing
- collect whole blood, urine and stool samples
- Where
- China
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Yibing Wang
Neuromotor Impairments, Cerebral Palsy
The FBRI VTC Neuromotor Research Clinic
The FBRI VTC Neuromotor Research Clinic was established and opened in May of 2013 to provide intensive therapeutic services to individuals with motor impairment secondary to neuromotor disorders. It is direct by Dr.
- Conditions
- Neuromotor Impairments, Cerebral Palsy, Microcephaly, Autism
- Trial name
- NCT03325946
- Testing
- ACQUIRE Therapy
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Virginia Polytechnic Institute and State University
Ankle Injuries
The Effects of Open Versus Closed Kinetic Chain Exercises on Ankle Joint Function
The goal of this Randomized clinical trial is to find the effects of open versus closed kinetic chain exercises on ankle joint function in athletes with chronic ankle instability.
- Trial name
- NCT05717426
- Testing
- Open chain exercises, Closed kinetic chain exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Sehat Medical Complex