Clinical trials: Chronobiology
Delayed Sleep-Wake Phase Disorder
Glasses for Adolescent Delayed Sleep-Wake Phase Disorder
The purpose of this study is to determine if evening amber glasses combined with stable wake times will show an increase in total sleep time (TST) and an advance in sleep onset times (shift earlier) compared to the control group.
- Trial name
- NCT04378933
- Testing
- Amber Glasses, Clear Lens Glasses
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
COPD, COPD Exacerbation
Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Patients with Chronic Obstructive Bronchopneumopathy.
Patients admitted in ICU may require invasive mechanical ventilation, using a mechanical ventilator and an endotracheal tube. In ICU, a prolonged duration of invasive mechanical ventilation may be responsible for…
- Conditions
- COPD, COPD Exacerbation, Ventilated Patients, Ventilator-Associated Pneumonia (VAP)
- Trial name
- SLEECOP (NCT06653933)
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Grenoble
Sleep Disorders, Circadian Rhythm
Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome
The purpose of this study is to evaluate the ability of ramelteon, once daily (QD), to advance the timing of sleep in individuals with delayed sleep phase syndrome.
- Trial name
- NCT00593736
- Testing
- Ramelteon
- Where
- 42 sites in United States
- Volunteers
- 132 people
- Sponsor
- Takeda
Sleep, Sleep Disturbance
Tech4Rest Trial With Team Truck Drivers
The current project is a safety and health intervention focused on sleep and fatigue among truck driver teams (pairs), where one driver sleeps in a moving vehicle while the other partner drives.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder, Shift Work, Health Knowledge, Attitudes, Practice
- Trial name
- Tech4Rest (NCT03108599)
- Testing
- Enhanced Cab, Fit4Sleep
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Delayed Sleep Phase Syndrome
Synchronization and Desynchronization Between Circadian Rhythms in Patients With Delayed Sleep Phase Syndrome (DSPS)
This study's first aim is to widen the knowledge of the characteristics of delayed sleep phase disorder (DSPS) by focusing on the circadian rhythms of appetite regulation factors and their phase relations to the cycles of…
- Trial name
- NCT00282061
- Testing
- Melatonin
- Where
- Israel
- Sponsor
- Sheba Medical Center
Depression, Sleep Disorders, Circadian Rhythm
Sleep-Wake Patterns on Illness Trajectories and Treatment Response in MDD
The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with MDD through clustering; (2)…
- Trial name
- NCT06181110
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Physiological Responses, Sleep Disorders, Circadian Rhythm
Effect of Owning a Service Dog on Military Veterans With PTSD
The study aims to investigate the effects of a service dog on military veterans with post traumatic stress syndrome (PTSD). The investigators will use non-invasive measures of the physiological responses, data obtained via dairy…
- Conditions
- Physiological Responses, Sleep Disorders, Circadian Rhythm, Stress, Emotional
- Trial name
- NCT05208008
- Testing
- With service dog
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
Skeletal Effects of Chronic Night Shift
The specific aim of this observational study is to characterize changes in bone turnover makers (BTMs), bone mineral density (BMD), and bone microarchitecture in a cohort of nurses during their first year of night compared to day…
- Trial name
- ACORN (NCT05091021)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Shift Work Type Circadian Rhythm Sleep Disorder, Chronobiology Disorders
Effects of Shift Work on Nurse Staff Health
Shift work deeply impacts on temporal organization leading to a circadian desynchronization, which translates into a worsening of the sleep quality and work ability during waking hours.
- Conditions
- Shift Work Type Circadian Rhythm Sleep Disorder, Chronobiology Disorders, Mood Swing, Physical Activity
- Trial name
- Turnisti (NCT03453398)
- Testing
- Shifts working hours with different schedules
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Healthy
Circadian System Heritability Assessed in Free Living Conditions
The purpose of this investigation is to assess the role of the genetic and environmental factor on circadian system, in free living conditions by the use of a female twin population.
- Trial name
- MTR (NCT03059576)
- Testing
- Chronobiological status of the subjects
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Universidad de Murcia
Bipolar Disorder
Circadian Rhythm Dysregulation in Offspring of Parents With Bipolar Disorder
This study aims to 1) investigate the differences and variances in circadian rhythms at several levels, including physical activity, dim light melatonin onset, diurnal patterns of cortisol, and body temperature between the…
- Trial name
- NCT03656302
- Where
- Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Shift-Work Sleep Disorder
Sleep Enhancement Training Study for Experienced Shiftworkers
The purpose of this study is to determine if a modified version of the Sleep Enhancement Fatigue Reduction Training (SEFRT) system can improve sleep and health-related symptoms and quality of life in experienced shift-working…
- Trial name
- SETS-exp (NCT00786357)
- Testing
- NIOSH shiftwork booklet, Sleep Enhancement Training System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Healthcare Workers, Stress Level
Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, Postural Stability and Sleep Quality in Shift Healthcare Workers
This study investigates the effects of virtual reality (VR)-based respiratory training on various physiological and cognitive functions in shift-working healthcare professionals, including paramedics and nurses.
- Conditions
- Healthcare Workers, Stress Level, Emergency Department, Shift Work Sleep Disorder
- Trial name
- NCT06926257
- Testing
- Experimental group (B) - breathing training using VR, Experimental group (C) - breathing training using relaxation music
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Recovery and Early Sleep Tracking Using the SuperPatch REM Patch
A Phase 1 Feasibility Study of the SuperPatch REM Patch for Post-Night-Shift Sleep Recovery in NHS Doctors
- Conditions
- Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Shift Work Sleep Disorders
- Trial name
- REST (NCT07785960)
- Testing
- SuperPatch REM Patch
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Sleep Disorders, Circadian Rhythm, Cognitive Dysfunction
Feasibility Study on the Use of Redormin®500 on Day-time Cognition
Randomized, double-blind, parallel groups, placebo-controlled, baseline/run-in period of 21 days followed by trial period of 21 days, digital phenotyping (sleep, cognitive/psychological parameters and HRV).
- Trial name
- NCT05684523
- Testing
- Valerian-Hop Extract
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Max Zeller Soehne AG
Smith Magenis Syndrome
Melatonin in Adults With SMS
Sleep-Wake and behavioral disorders in Smith Magenis Syndrome (SMS) are strongly linked to an inversion of the nychtemeral secretion of melatonin. This inversion have been described in children with SMS.
- Trial name
- SMS-adults (NCT03492970)
- Testing
- Hourly dosing of the nychtemeral secretion of melatonin
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hôpital le Vinatier
Morning Operation, Evening Operation
Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
General anesthesia is a medically induced state of low reactivity consciousness involving amnesia, immobility, unconsciousness, and analgesia, which is similar to natural sleep.
- Conditions
- Morning Operation, Evening Operation, Sleep Quality, General Anesthesia
- Trial name
- NCT04094376
- Testing
- receiving operation during the day or at night
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Delayed Sleep Phase Syndrome
Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P2 (NCT04792697)
- Testing
- Increase morning bright light, Decrease evening blue light, Sleep Scheduling
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sleep Wake Disorders, Circadian Rhythm Disorders
Implementing and Sustaining a Sleep Treatment to Improve Community Mental Health Part 3: Sustainment
Research on the sustainment of implemented evidence-based psychological treatments in routine practice settings, such as community mental health centers, is limited.
- Trial name
- NCT05956678
- Testing
- Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C), Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)
- Where
- 10 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder
Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
Open-label Study to Investigate the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents.
- Conditions
- Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder, Autism Spectrum Disorder, Smith-Magenis Syndrome
- Trial name
- NCT02776215
- Testing
- tasimelteon
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanda Pharmaceuticals