Clinical trials: Cigarette Smoker
Periodontitis, Smoking ( Cigarette)
Effect of Non-Surgical Periodontal Therapy on Salivary Biomarkers in Smokers and Non-Smokers With Periodontitis
This study evaluates the effect of non-surgical periodontal therapy on salivary biomarkers (Dkk-1, Sclerostin, and PLAP-1) and clinical periodontal parameters in patients with periodontitis.
- Trial name
- NSPT-Biomarker (NCT07547202)
- Testing
- Non-surgical periodontal therapy (Scaling and root planing)
- Where
- 2 sites in Iraq
- Volunteers
- 44 people
- Sponsor
- Al-Mustansiriyah University
Smoking, Cigarette, Smoking Cessation
A Cognitive Behavioral Stress Intervention for Women Who Smoke
1. PURPOSE OF THE STUDY 1.1 Justification The purpose of the project is to examine the effect of breathing biofeedback and thoughts about stress on performance under stress and cigarette cravings.
- Conditions
- Smoking, Cigarette, Smoking Cessation, Stress, Stress, Emotional
- Trial name
- NCT03077945
- Testing
- heart rate variability biofeedback and cognitive reappraisal, control tasks
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smoking Cessation, Nicotine Dependence
Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment
This research study will evaluate the preliminary efficacy of Pride Posts Plus, a social media-based smoking cessation treatment.
- Conditions
- Smoking Cessation, Nicotine Dependence, Tobacco Use, Cigarette Smoking
- Trial name
- NCT04461288
- Testing
- Social media-based education, counseling, and support, Nicotine replacement therapies (NRT), Gamification
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
COPD, Smoking
Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke
Cigarette smoking is the major risk factor for developing chronic obstructive pulmonary disease (COPD). Patients with COPD have difficulty clearing mucus and debris from their airways.
- Trial name
- NCT02168673
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cigarette Smoking, Drug Use
Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment
The objective of the proposed project is to develop a novel, behavioral approach to smoking cessation that can be integrated with residential drug use treatment for low income substance using smokers with elevated depressive…
- Trial name
- BA-DAS (NCT01372254)
- Testing
- Standard Treatment, BAD-AS, Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Maryland, College Park
Tobacco Abuse
Decision Aid for Cigarette Smokers Undergoing Surgery
Smokers have three choices when faced with surgery: keep smoking, quit for a short time around surgery or quit for good. In the first specific aim, a decision aid was designed to help facilitate the discussion of these choices…
- Trial name
- NCT01575119
- Testing
- Decision Aid, Control intervention, Control
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Mayo Clinic
Cardiovascular Disease, Insulin Resistance
Insulin Resistance in Smokers Undergoing Smoking Cessation
Cigarette smoking increases CVD risk and worsens insulin resistance, but also contributes to weight loss; smoking cessation reduces CVD risk and improves insulin sensitivity, but also contributes to weight gain.
- Trial name
- NCT00877513
- Testing
- Smoking cessation
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Charles Drew University of Medicine and Science
Electronic Cigarette Use
Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)
The purpose of this study is to determine if abuse liability indices will be impacted by varying flavors and e-cigarette (ECIG) nicotine delivery capability (i.e., nicotine flux) among current combustible cigarette users.
- Trial name
- NCT05971823
- Testing
- Tobacco product administration and assessment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Cigarette Smoker, Current Smoker
Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer
This randomized clinical trial studies the Beating Lung Cancer in Ohio protocol in improving survival in patients with stage IV non-small cell lung cancer.
- Conditions
- Cigarette Smoker, Current Smoker, Lung Adenocarcinoma, Squamous Cell Lung Carcinoma
- Trial name
- BLCIO (NCT03199651)
- Testing
- Best Practice, Biospecimen Collection, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 3,584 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking Cessation, Electronic Cigarette
Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers
Abstract Rationale. Electronic cigarette use is increasing at an exponential rate in Finland and internationally. The health consequences of vaporised aerosols in electronic cigarettes are largely unknown especially in a long…
- Trial name
- EFFECT (NCT03235505)
- Testing
- Nicotine, Varenicline Tartrate, Motivational Interview
- Where
- Finland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Cigarette Smoking
Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers
The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking
- Trial name
- NCT00843622
- Testing
- Low-nitrosamine smokefree tobacco product for oral use
- Where
- 4 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB
Cigarette Smoking, Schizophrenia
Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness
The overall aim of this study is to test the effect of academic detailing (i.e. provider-level educational intervention focused on evidence-based smoking cessation treatment for those with psychiatric illness) and community…
- Conditions
- Cigarette Smoking, Schizophrenia, Bipolar Disorder, Depressive Disorder, Major
- Trial name
- NCT02845440
- Testing
- Academic Detailing, Community Health Worker, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 1,165 people
- Sponsor
- Massachusetts General Hospital
Vascular Reactivity, Serum Biomarkers
MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers
To examine vascular reactivity and inflammatory biomarkers via quantitative magnetic resonance imaging (MRI) and blood serum, respectively, in a crossover study where active vapers (electronic cigarette users) and smokers will…
- Trial name
- AeCE (NCT05271578)
- Testing
- Standardized Electronic Research Cigarette, Nicotine Research Cigarette
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking Cessation, Smoking, Tobacco
Helping Poor Smokers Quit
Using a 2x2 randomized factorial design, we will conduct a statewide field trial in Missouri to compare the relative and combined effects of these two strategies for augmenting an existing, evidence-based tobacco quitline…
- Conditions
- Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette, Smoking, Pipe
- Trial name
- NCT03194958
- Testing
- Specialized Quitline, Basic Needs Navigator
- Where
- United States
- Volunteers
- 1,944 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Smoking, Exercise Capacity
Effect of Switching From Cigarette Smoking to IQOS on Exercise Capacity
This exploratory study is part of the global clinical assessment program of IQOS. It was designed to provide scientific evidence to further substantiate the reduced risk potential of using a heated tobacco product (the Tobacco…
- Trial name
- NCT03887117
- Testing
- IQOS + Exercise Training Program, IQOS without Exercise Training Program, Cigarette Smoking + Exercise Training Program
- Where
- Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Nicotine Dependence
Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Smokers
Background: Multiple social, psychological, and environmental factors contribute to adolescents' use of cigarettes. Environmental smoking cues have been shown to play an important role in the maintenance of nicotine addiction and…
- Trial name
- NCT01148355
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking, Tobacco Use
Salt-Based E-cigarette
Electronic nicotine delivery systems (ENDS) vary on a wide range of characteristics, which may impact the reinforcement value of the products compared to more harmful combustible products.
- Trial name
- NCT04238832
- Testing
- Salt Base Nicotine, Free Base Nicotine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking
Reduced Exposure Study in Smokers Using the Tobacco Heating System 2.2 (THS 2.2) for 5 Days in a Confinement Setting
The overall goal of the study is to evaluate if the ad libitum use of the Tobacco Heating System 2.2 (THS 2.2) for 5 consecutive days by adult Japanese healthy smokers affects the levels of biomarkers of exposure for selected…
- Trial name
- NCT01970982
- Testing
- Tobacco Heating System (THS 2.2), Smoking abstinence (SA), Conventional cigarette (CC)
- Where
- Japan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Nicotine Dependence, Smoking
Effect Of Nicotine on Neurocognitive Performance of Cigarette Smokers
This research project addresses the hypothesis that a neurocognitive profile characterized by impairment of response inhibition and sustained attention may be a risk factor for smoking initiation and nicotine dependence among…
- Conditions
- Nicotine Dependence, Smoking, Tobacco Use Disorder, Nicotine Use Disorder
- Trial name
- NCT00429208
- Testing
- Nicotine
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization