Clinical trials: Cigarette Smoker
Tobacco Smoking, Healthy Participants
Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model
The purpose of this pilot study is to evaluate allergen-induced nasal airway inflammation following nasal application of felis domesticus, or cat, extract in e-cigarette users, cigarette smokers, and non-smokers.
- Conditions
- Tobacco Smoking, Healthy Participants, E-cigarette Smokers
- Trial name
- Kitty Nose (NCT03031145)
- Testing
- Felis Domesticus
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Smoking
Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting
The main goal of the study is to evaluate if the ad libitum use of the THS 2.2 Menthol (mTHS 2.2) for 5 days in confinement and after 85 days of product use in an ambulatory setting, by Japanese adult healthy smokers results in a…
- Trial name
- NCT01970995
- Testing
- THS 2.2 Menthol (mTHS 2.2), Smoking Abstinence (SA), Menthol Conventional Cigarette (mCC)
- Where
- Japan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Tobacco Smoking Behavior
Novel Approaches to Reducing Tobacco Related Harm
The purpose of this study is to assess initial reactions to alternative nicotine/tobacco products among smokers living with HIV.
- Conditions
- Smoking, Tobacco Smoking Behavior, Cigarette Smoking
- Trial name
- NCT02600273
- Testing
- Usual brand cigarettes, Lower nicotine content cigarettes, Electronic cigarettes 1
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
Smoking, Tobacco Smoking
Reduced Exposure to HPHC in Smokers Switching From Cigarettes to Different Versions of THS
This was a randomized, controlled, open-label, 4 parallel arm study with a stratified randomization by sex (a quota for each sex [females and males] of at least 40% overall).
- Conditions
- Smoking, Tobacco Smoking, Tobacco Use
- Trial name
- NCT05599451
- Testing
- THS Blade device, THS Induction Mono device, THS Induction Mid device
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Cigarette Smoking
A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation
The purpose of this study was to understand the biological and functional changes after one year of smoking cessation and to collect data on a broad range of biomarkers of exposure (BoExp) and biomarkers of effect (BoE).
- Trial name
- RIBESC (NCT02432729)
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Toxicant Exposure
Effects Among Smokers Who Use and Do Not Use E-Cigarettes
This study compares effects among Latino and African American cigarette smokers who use e-cigarettes with those who continue smoking as usual.
- Trial name
- NCT03511001
- Testing
- E-Cigarette Vs. Smoking as Usual
- Where
- 2 sites in United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- California State University, San Marcos
Smoking, Elective Surgery
Decision Aid Development for Smokers
A decision aid tool will be developed using participatory research approach. The decision aid will be targeted to cigarette smokers scheduled for elective surgery.
- Trial name
- NCT01193972
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Smoking Cessation, Tobacco Use Cessation
Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)
The primary study objective is to demonstrate the efficacy of dianicline as an aid to smoking cessation in cigarette smokers. The main secondary objectives are to assess the: craving for cigarettes, nicotine withdrawal symptoms…
- Trial name
- NCT00387946
- Testing
- SSR591813L (dianicline)
- Where
- 2 sites in United States, Canada
- Volunteers
- 630 people
- Sponsor
- Sanofi
Smoking, Tobacco, Smoking
GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments
The purpose of the study is to learn more about the relationships between the brain, behavior, and natural daily exposure to particular environments, including the places where smokers regularly spend time and specific retail…
- Conditions
- Smoking, Tobacco, Smoking, Smoking, Cigarette
- Trial name
- NCT04279483
- Testing
- Tobacco retailer, Non-tobacco retailer
- Where
- United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cigarette Smoking, Tobacco Smoking
A Study of Unfiltered Cigarettes Among Committed Smokers
This study is an open-label, randomized, 9-week, two-sequence, two-treatment, cross-over clinical trial of 40 adult filtered cigarette smokers who switch to unfiltered cigarettes There will be a 1-week baseline period, 2 weeks of…
- Trial name
- NCT03749876
- Testing
- Unfiltered Cigarettes, Filtered Cigarettes
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Dental Implants, Cigarette Smoking
Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers
The purpose of this trial was to determine the effect of a triclosan-containing toothpaste in the clinical parameters and in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) as a…
- Trial name
- NCT03241407
- Testing
- triclosan/copolymer/fluoride toothpaste
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Paulista University
Cigarette Smoking
Tailored Web and Peer Email Cessation Counseling for College Smokers
The RealU2 is a randomized controlled trial to determine the efficacy of an online health and wellness program for young adults with the addition of individualized peer health coaching.
- Trial name
- RealU (NCT01604525)
- Testing
- Tailored Web, Peer Coaching, Untailored Web
- Volunteers
- 1,699 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cigarette Smoking, Post Traumatic Stress Disorder
Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster
The purpose of this study was to test the efficacy of a CBT-based smoking cessation treatment enhanced with transdiagnostic skills for the management of anxiety and fear-based avoidance behaviors (CBT-A) relative to a standard…
- Conditions
- Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
- Trial name
- NCT02538601
- Testing
- CBT-A, CBT-S
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stony Brook University
Tobacco Use
Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers
The objective of this study is to examine whether cigarette packaging regulations including graphic health warning labels on cigarette packs and requiring plain, unbranded packaging reduce the appeal of cigarettes and prompt…
- Trial name
- NCT03446170
- Testing
- Graphic cigarette warning labels, plain packaging
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Georgetown University
Hiv, Cigarette Smoking
Cultural Adaptation and Piloting of a Smoking Cessation Intervention for Smokers With HIV
One population of tobacco users that is severely affected by the consequences of smoking is people living with HIV (PLWH). Between 40-84% of PLWH smoke, a percentage that has remained constant since the first studies of smoking…
- Trial name
- NCT03580460
- Testing
- Computer delivered smoking cessation counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases
Chronic and Acute Effects of Smoking on the Left and Right Ventricular Relaxation in Young Healthy Smokers
Impairment of relaxation, the early phase of ventricular diastole is the first stage of heart diastolic dysfunction. Left ventricular diastolic function can be determined noninvasively by Echo- Doppler - derived mitral valve flow…
- Trial name
- NCT00395928
- Where
- Poland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Smoking Cessation
Quit Smoking: Optimizing Health Promotion Strategy
The goal of this factorial trail is to to optimize an intervention package to enhance quit attempt preparations, quit attempts, and tobacco abstinence among smokers without a plan to quit.
- Trial name
- NCT06077058
- Testing
- Nicotine Replace Therapy (NRT) sampling, Simple exercise education (SEE), Chat-based instant messaging
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Biomarkers
Changes in Biomarkers Associated With Use of Electronic Cigarettes
The objective of this clinical trial was to compare the effects of e-cigarettes with and without nicotine on patterns of combustible cigarette use and biomarkers of exposure to tobacco toxicants among African American smokers.
- Trial name
- NCT03084315
- Testing
- E-Cig Zero Nicotine, E-Cig 24mg Nicotine
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Maintaining Abstinence in Chronic Cigarette Smokers - 1
The purpose of this study is to evaluate the extended pharmacological and psychological treatment for chronic cigarette smokers.
- Trial name
- NCT00087880
- Testing
- Bupropion and NRT
- Where
- United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cigarette Smoker, Current Every Day Smoker
APPSPIRE App in Preventing Students From Smoking
This trial studies how well APPSPIRE, a smartphone app, works in preventing students from smoking. Technology-driven intervention programs, such as the APPSPIRE app, have the potential to increase access to health behavior…
- Conditions
- Cigarette Smoker, Current Every Day Smoker, Student
- Trial name
- NCT01967082
- Testing
- APPSPIRE, Focus Group, Survey Administration
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center