Clinical trials: Cigarette Smoker
Smoking
Comparison of Pharmacokinetic Parameters Between Adopters of Electronic Cigarettes and a Historical Sample of Combustible Cigarette Smokers
This study assesses the nicotine pharmacokinetic (PK) parameters in adopters of electronic cigarettes following a 12-hour tobacco and nicotine abstinence.
- Trial name
- NCT02730676
- Testing
- Electronic Cigarette #1, Electronic Cigarette #2
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Vapor Company
Waterpipe Smoking, Oxidative Stress
Carbon Monoxide and Oxidative Stress in Waterpipe Smokers
Waterpipe is a tool for smoking tobacco, which is thought to be less harmful than cigarette. Unfortunately, there aren't adequate studies about its harms to health that are threatening the young generation all over the world…
- Trial name
- NCT02937415
- Testing
- Breath carbon monoxide, Pulmonary function tests., Oxidative stress and antioxidant status.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk Training and Research Hospital
Smokers
Study to Evaluate the Efficacy, Safety, Tolerability and Immunogenicity of 100µg NIC002 Vaccine in Cigarette Smokers Who Are Motivated to Quit Smoking.
This study is designed to determine the efficacy of high nicotine-specific antibody titers in smoking cessation.
- Trial name
- NCT00736047
- Testing
- NIC002
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Novartis
HEAVY TOBACCO SMOKERS
Docosahexaenoic Acid (DHA) Effects on Cognitive Function, Craving and Psychosocial Factors in Heavy Cigarette Smokers
The purpose of this study is to assess effects of Docosahexaenoic Acid (DHA) as an add-on novel supplement on quality of life, cognitive function, craving and psychosocial factors in heavy cigarette smokers.
- Trial name
- NCT01284660
- Testing
- DHA
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Electronic Cigarettes
Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users
The purpose of this research study is to find out how different types of electronic cigarettes (ECIG) settings, combined with e-liquids of differing nicotine concentrations, affect blood nicotine levels, use behavior (how users…
- Trial name
- NCT03710590
- Testing
- ECIG Lab Session 15 watts, 10 mg nicotine, ECIG Lab Session 15 watts, 15 mg nicotine, ECIG Lab Session 15 watts, 30 mg nicotine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Concentration of Exhaled Carbon Monoxide
Effect of Face Mask on Exhaled Carbon Monoxide of Smokers
Study of 120 healthy subjects without cardiovascular disease, 40 smokers of conventional cigarettes, 40 exclusive users of Heat-non-Burn Cigarettes and 40 nonsmokers.
- Trial name
- NCT04966845
- Testing
- measurement of concentration on exhaled Carbon Monoxide
- Where
- 2 sites in Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Smoking Cessation
Evaluation of Cessation Preferences of Menthol Smoker
The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, mint-flavored nicotine gum; non-flavored nicotine gum; mentholated nicotine inhaler…
- Trial name
- NCT02020005
- Testing
- Non-flavored 2mg nicotine gum, Non-flavored 4mg nicotine gum, Mint-flavored 2mg nicotine gum
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Cardiovascular Disease, Insulin Resistance
Insulin Resistance in Smokers Undergoing Smoking Cessation
Cigarette smoking increases CVD risk and worsens insulin resistance, but also contributes to weight loss; smoking cessation reduces CVD risk and improves insulin sensitivity, but also contributes to weight gain.
- Trial name
- NCT00877513
- Testing
- Smoking cessation
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Charles Drew University of Medicine and Science
Nicotine Dependence, Smoking
Effect Of Nicotine on Neurocognitive Performance of Cigarette Smokers
This research project addresses the hypothesis that a neurocognitive profile characterized by impairment of response inhibition and sustained attention may be a risk factor for smoking initiation and nicotine dependence among…
- Conditions
- Nicotine Dependence, Smoking, Tobacco Use Disorder, Nicotine Use Disorder
- Trial name
- NCT00429208
- Testing
- Nicotine
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Field Cancerization for Cannabis Smokers
Effect of Cannabis and Cigarette Smoking on Oral Mucosa
The aim of this study is to detect P53 expression in clinically normal oral mucosa of cigarette smokers, simultaneous cigarette and cannabis smokers and non-smokers as a surrogate marker for field cancerization.
- Trial name
- NCT03334279
- Testing
- Cigarette smokers, Simultaneous cigarette and cannabis smokers
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Smoking, Non-smoking
Smoking Research Study
The purpose of this study is to develop a fit-for-purpose biochemical verification tool that can be used to detect concomitant use of a few (less than 5) conventional cigarettes.
- Trial name
- NCT01465880
- Testing
- Part A
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Current Smoker, Never Smoker
Effects of Electronic Cigarette Use on the Lungs
This randomized pilot clinical trial studies the effects of electronic cigarettes on the lungs. Studying the effects of electronic cigarettes on the lungs may provide the Food and Drug Administration (FDA) and other government…
- Conditions
- Current Smoker, Never Smoker, Tobacco Use Disorder, Former Smoker
- Trial name
- NCT02596685
- Testing
- Bronchoscopy, Electronic Cigarette, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma, Malignant Thoracic Neoplasm
A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer
This clinical trial evaluates the feasibility of a novel tobacco cessation resource called a Buckeye Quit Stick among smokers with a diagnosed or suspected thoracic cancer.
- Trial name
- NCT07455513
- Testing
- Electronic Health Record Review, Informational Intervention, Interview
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking, Nicotine Dependence
Comparison of Internet Stop Smoking Intervention to Usual Care on Smoking Cessation at 6 Months
The primary goal of this project is to carry out a randomized controlled trial (RCT) comparing quit rates of a Spanish/English stop smoking Web site to those of a no-intervention or "quit on your own" control.
- Trial name
- TC5Redes (NCT01639079)
- Testing
- Internet Smoking Cessation Web Site
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Dependence
S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence
Cigarette smoking is of great public health importance and is the single most important preventable cause of morbidity, mortality and excess health care costs in the United States.
- Trial name
- NCT00722124
- Testing
- S-Adenosyl-L-Methionine
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cigarette Smoking
Reaching and Treating Lesbian, Gay, Bisexual, and Transgender (LGBT) Cigarette Smokers
Smoking rates are significantly higher among lesbian, gay, bisexual, and transgender (LGBT) populations compared to the general population.
- Trial name
- NCT00634218
- Testing
- Mail-based Self-help plus Internet-based Smoking Treatment, Self-Help Manual plus Telephone counseling, Self-Help Manual
- Where
- United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use, Tobacco Smoking
A Study to Characterize Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouches in Adult Cigarette Smokers
This study is designed to evaluate plasma nicotine pharmacokinetic (PK) parameters following the use of nicotine pouches in cigarette smokers who have experience with use of smokeless tobacco (SST) [e.g., snus, moist snuff].
- Trial name
- NCT04846088
- Testing
- Product A, Product B, Product C
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
E-cigarettes
Acute Response to Cigarette and E-cigarette Smoking Assesed in Exhaled Breath Condensate in Healthy Smokers of Traditional and E-cigarettes
Electronical cigarettes, also known as "e-cigarettes" are a new phenomenon, which steadily wins more aprobation among smokers. However, there exists no much data concerning the effects of acute exposure to electronic cigarettes…
- Trial name
- NCT03153228
- Where
- Poland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
Vaping and Smoking Withdrawal Project
The proposed research, which will systematically and comprehensively characterize the withdrawal among daily vapers compared to daily smokers of combustible cigarettes, filling critical gaps in the understanding of electronic…
- Trial name
- VASP (NCT05772845)
- Testing
- Acute (24-hour) abstinence, Ad libitum smoking/vaping
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
COPD
Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study
Chronic obstructive pulmonary disease (COPD) is a common inflammatory disease of the airway affecting approximately 10% of individuals aged 40 years or more with a smoking history.
- Trial name
- NCT01780298
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.