Clinical trials: Circadian Rhythm Sleep-Wake Disorder
Alzheimer's Disease (AD), Sleep Disorders, Circadian Rhythm
Improvement of Sleep Disorders in Patients With Alzheimer's Disease After Sunlight Exposure Therapy.
This observational study aimed to understand the effect of intervention A on sleep disorders in individuals with Alzheimer's disease receiving sunlight therapy.
- Trial name
- NCT07386808
- Testing
- sunlight therapy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Depression
Effects of Light Treatment During Sleep on Young Men
This study will determine if green light exposure during sleep is effective in reducing mild depression symptoms in young men.
- Trial name
- NCT00796939
- Testing
- Green light mask, Red Light Mask
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Intensive Care Unit, Ventilator
Effects of Light and Sound Modification on Sleep Quality and Circadian Rhythm in the MICU Patients
This study will investigate the effectiveness of light and sound modification in improving sleep qualit , and circadian rhythms in MICU patients with Mechanical Ventilation in Taiwan. Hypothesis: 1.
- Conditions
- Intensive Care Unit, Ventilator, Sleep Quality, Circadian Rhythm
- Trial name
- MICU (NCT04129918)
- Testing
- light and sound modification (earplugs and eye masks)
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Sleep Initiation and Maintenance Disorders
Effects of Melatonin on Insomnia Symptoms in Older Adults
This study will determine whether melatonin tablets will increase the sleep of older adults with insomnia.
- Trial name
- NCT00230737
- Testing
- Melatonin 0.4 mg, Melatonin 4.0 mg
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Nalaka Gooneratne
Breast Cancer, Circadian Rhythms
The Effects of Light Therapy to Treat Cancer-related Side Effects
Severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment.
- Conditions
- Breast Cancer, Circadian Rhythms, Fatigue, Sleep Disturbance
- Trial name
- NCT04418856
- Testing
- Light Glasses (Experimental), Light Glasses (Comparison)
- Where
- Iceland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Shift Work Type Circadian Rhythm Sleep Disorder, Imbalance of Constituents of Food Intake
Meal Distribution Across the Day in Female Nurses Working Shifts
This study assessed the meal distribution across the day (energy and macronutrient intake) and its relationship to the nutritional status of nursing professionals.
- Trial name
- NCT02522195
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Psychological Stress, Physiological Stress
Bright Light Intervention to Reduce Students' Stress
Increased stress levels are a significant problem for many students and represent a risk factor for impaired mental and physical health as well as academic performance.
- Conditions
- Psychological Stress, Physiological Stress, Sleep Disorders, Circadian Rhythm
- Trial name
- BLISS (NCT04900675)
- Testing
- Bright light intervention
- Where
- Austria
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universitaet Innsbruck
Non-24 Hour Sleep-Wake Disorder, Blindness
Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects
The aim of this placebo-controlled randomized study was to evaluate the efficacy of Circadin™ 2 mg in improving total night sleep duration and stabilizing the circadian clock phase in totally blind subjects with non-24 hour…
- Trial name
- NCT00972075
- Testing
- melatonin (Circadin)
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Obstructive Sleep Apnea (OSA), Insomnia
Validating the Use of a Subjectively Reported Sleep Vital Sign
Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will…
- Conditions
- Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder
- Trial name
- SVS (NCT03018912)
- Testing
- Sleep VS
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Delayed Sleep Phase Syndrome
Lemborexant in Delayed Sleep Phase Syndrome
The purpose of the study is to evaluate whether Lemborexant is more effective than placebo in shortening sleep onset latency in patients with delayed sleep phase syndrome (both type 1 and type 2).
- Trial name
- NCT05463861
- Testing
- Lemborexant
- Where
- 2 sites in United States
- Volunteers
- 86 people
- Sponsor
- Stanford University
Delayed Sleep Phase Disorder, Jet-lag
Melatonin Treatment for Induced Transient Insomnia
Melatonin supplements have been reported to be an effective treatment for circadian rhythm sleep disorders, including shift work dyssomnia, jet-lag, delayed sleep phase syndrome, and sleep disruption suffered by many blind…
- Conditions
- Delayed Sleep Phase Disorder, Jet-lag, Shift-work Disorder
- Trial name
- NCT00950885
- Testing
- Low Dose Melatonin, High Dose Melatonin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Traditional Chinese Medicine, Insomnia
Insomnia Treated by Traditional Chinese Medicine and Its Circadian Rhythm
Insomnia and sleep disorders are prominent health problems in modern society. High working pressure, fast pace of life, the use of electronic products and other reasons lead to the high incidence of insomnia and sleep disorders…
- Conditions
- Traditional Chinese Medicine, Insomnia, Circadian Rhythm
- Trial name
- NCT04448197
- Testing
- Chinese Medicine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Non-24-Hour-Sleep-Wake Disorder
Open Label Study to Assess the Absolute Bioavailability of Tasimelteon (HETLIOZ™)
Hetlioz™ (tasimelteon) is used in the treatment of Non-24-Hour-Sleep-Wake Disorder (Non-24). Non-24 is very common in people who are totally blind because light can not reset their body clock.
- Trial name
- NCT02130999
- Testing
- tasimelteon 20 mg capsule, tasimelteon 2 mg I.V.
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Dementia, Alzheimer Disease
Zolpidem CR and Hospitalized Patients With Dementia
The purpose of this research study is to compare the effectiveness of Zolpidem CR to that of placebo in improving sleep efficiency in people with dementia admitted to the hospital because of their symptoms.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Sleep Disorders
- Trial name
- NCT00814502
- Testing
- Zolpidem CR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Critical Illness, Sleep Deprivation
Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients
The goal of this project is to determine whether the sleep and circadian rhythms of critically ill patients undergoing mechanical ventilation can be improved through practical strategies that can be employed at the bedside.
- Conditions
- Critical Illness, Sleep Deprivation, Respiratory Failure, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT01284140
- Testing
- Sleep and circadian rhythm promotion, Usual care
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Brian Gehlbach
Shift Work Type Circadian Rhythm Sleep Disorder, Eating Behavior
Eating Behaviors in Shift Workers
This study will compare eating behaviors and measures of hunger and fullness between day and night workers in order to better understand why night workers are at increased risk for obesity and related diseases.
- Trial name
- NCT04468672
- Testing
- Portion size
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Shift Work Type Circadian Rhythm Sleep Disorder
Determination of Protocol of Nocturnal Food Intake of Shift Workers.
This study evaluates the effect of different dietary conducts in the nocturnal period on the postprandial metabolism and food perceptions of night workers of the Hospital of Clinics of Uberlândia, Federal University of Uberlândia.
- Trial name
- NCT03456219
- Testing
- Normal protein diet, High-protein diet
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Insomnia Chronic, Sleep Disorder
Light Therapy for Chronic Insomnia in General Practice
Sleep disorders, especially insomnia Attention deficits (or disorders), daytime somnolence and drug dependence The goal is to evaluate whether light therapy could be used as an efficient alternative treatment with direct…
- Conditions
- Insomnia Chronic, Sleep Disorder, Circadian Rhythm Disorders
- Trial name
- Insolux (NCT04612192)
- Testing
- Active luminette
- Where
- 3 sites in France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Strasbourg, France