Clinical trials: Circadian Timing
Young Adults, Hypertension
Examining the Circadian Timing Effects of the Hypotensive Response to Exercise
The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns.
- Conditions
- Young Adults, Hypertension, Post-Exercise Hypotension, Circadian Rhythm
- Trial name
- XTIME (NCT07049783)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Freda Patterson
Circadian Rhythm Sleep Disorder, Circadian Rhythm Disorder Caused by Drug
Changes in Circadian Rhythm After Anaesthesia in Children
In this study the investigators will examine the effect of general anesthesia and surgery on sleep duration and sleep quality in children, using questionnaires and a sleep diary.
- Conditions
- Circadian Rhythm Sleep Disorder, Circadian Rhythm Disorder Caused by Drug, Circadian Rhythm Sleep Disorder, Jet Lag Type, Jet Lag
- Trial name
- CLOCKSkids (NCT05618405)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Sleep Restriction
Impact of a Sleep Debt in Middle-Aged and Older Adults
This project has 6 aims. 1. To examine the impact of recurrent partial sleep loss in young, middle-aged and older men and women. Sleep will be restricted to 4 hours. 2.
- Trial name
- PPG (NCT00817700)
- Testing
- Sleep restriction
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Critical Illness, Cognitive Impairment
Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors
More than 60% of intensive care unit (ICU) patients are adults ages 60 and older, who are at high risk for ICU-acquired cognitive impairment.
- Conditions
- Critical Illness, Cognitive Impairment, Circadian Dysrhythmia, Intensive Care Unit Delirium
- Trial name
- OPTIMIZE (NCT05467410)
- Testing
- COG-AM, COG-PM
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Overweight and Obesity, Type 2 Diabetes
Hedonic and Homeostatic Appetite Control in Obesity and Type 2 Diabetes in the Context of Meal and Exercise Timing
The overall aim is to investigate effects of acute exercise on ad libitum energy intake and study whether this differs between morning and evening in individuals with overweight/obesity with or without type 2 diabetes (T2D).
- Trial name
- TIMEX (NCT05768958)
- Testing
- Exercise, Control
- Where
- Denmark
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
ADHD
Impact of Short and Mistimed Sleep on Adolescents With ADHD: The Adolescent Attention and Circadian Timing Study
Many adolescents go to bed late and wake up early for school. Science is only beginning to understand how sleep schedules can affect them.
- Trial name
- AACT (NCT07684417)
- Testing
- Aligned sleep extension, Misaligned sleep extension
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronobiology Disorders, Circadian Rhythm Disorders
Light Sensitization Study
Circadian rhythm disorders are a class of sleep disorders characterized by misalignment between the timing of sleep and the timing of rhythms driven by the biological clock.
- Conditions
- Chronobiology Disorders, Circadian Rhythm Disorders, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT01327040
- Testing
- light exposure
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Deprivation, Obesity
Sleep and Metabolism
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to…
- Conditions
- Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain
- Trial name
- SAM (NCT05775627)
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Brain Injuries, Traumatic, Sleep Initiation and Maintenance Disorders
The Feasibility of Home-Based Measurement of Circadian Timing for Veterans With TBI and Insomnia
Veterans with traumatic brain injury (TBI) frequently experience insomnia, which is linked with delayed TBI recovery, more severe functional impairment, and exacerbation of disabling TBI after-effects such as depression, chronic…
- Trial name
- Home DLMO (NCT05665764)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- VA Office of Research and Development
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Shift-Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Breath Biomarkers for Sleep Loss and Circadian Timing
Insufficient sleep has both health and safety risks, but currently there are no quick, accurate and inexpensive ways to measure sleep deficiency.
- Conditions
- Shift-Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Intrinsic
- Trial name
- NCT03980340
- Testing
- Short Nap Intervention, No Nap Intervention
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity
Sleep Timing and Insulin Resistance in Adolescents With Obesity
This study examines the relationship between sleep timing and insulin resistance in adolescents with obesity. The investigators also aim to develop a physiologically-based mathematical model of adolescent sleep/wake and circadian…
- Trial name
- NCT02585830
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Circadian Rhythm, Energy Balance
Timing and Resistance Exercise: Impact on Eating and Metabolism
Exercise timing (morning or evening) for optimal weight control is a research topic urgently addressed by scholars in the relevant field.
- Conditions
- Circadian Rhythm, Energy Balance, Appetitive Behavior, Food Reward
- Trial name
- NCT06549322
- Testing
- The exercise in morning, The exercise in evening
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Obesity, Overweight
Effects of Meal Energy Density on Body Measures and Metabolism in Women
This study investigates whether the timing of energy intake during the day-specifically consuming more calories at breakfast or at dinner-affects body measurements, blood sugar levels, cholesterol, and feelings of hunger in women…
- Conditions
- Obesity, Overweight, Appetite Regulation, Meal Timing
- Trial name
- NCT07066618
- Testing
- Breakfast-Loaded Hypocaloric Diet, Dinner-Loaded Hypocaloric Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Melike Nur Eroğlu
Obesity, Sarcopenia
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes
The aim of TIMEDIAB is to demonstrate that early TRE (eTRE) combined to late (afternoon) exercise will outperform eTRE combined to morning exercise on muscle function as primary endpoint, and glucose homeostasis as secondary…
- Conditions
- Obesity, Sarcopenia, Post Menopause, Type 2 Diabetes
- Trial name
- TIMEDIAB (NCT07075133)
- Testing
- Antidiabetic diet (control), eTRE diet, Physical activity in the morning
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse