Clinical trials: Circulatory Shock
Tendinopathy
Shock Wave Therapy for Sural Myofascial Pain Associated to Chronic Heel Pain
The aim of this randomized controlled study in to investigate if a shock wave treatment extended to the gastrocnemius-soleus trigger points (TrP) is more effective than a standard treatment exclusively targeted at the plantar…
- Trial name
- NCT04385329
- Testing
- Shock wave therapy on plantar fascia extended to the gastrocnemius-soleus trigger points, Shock wave therapy on plantar fascia only
- Volunteers
- 55 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Shock Circulatory, Cardiogenic Shock
Left Ventricular Outflow Tract Mean Velocity in Children: a Strong Alternative to Cardiac Index in Pediatric Intensive Care Unit
Objectives: Noninvasive assessment of cardiac index (CI) in pediatric critical ill patient is crucial. Aortic Velocity Time Integral (VTI) valuable in adults, faces age and heart rate variability challenges in pediatrics…
- Trial name
- NCT06837727
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Septic Shock
Assessment of Cardiac Output and Stroke Volume in Septic Shock Patients
The aim of this research is to compare the accuracy and reliability of electrical cardiometry versus transthoracic echocardiography in measuring cardiac output and stroke volume in patients with septic shock, to evaluate the…
- Trial name
- NCT07321405
- Testing
- echocardiogram, Electrical cardiometry
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Spasticity, Muscle
Does ESWT With BoNTA Treatment Improve Outcomes When Compared to Standard Management for Upper Limb Spasticity Patient.
Background Effective management of spasticity, a debilitating and challenging condition afflicting many recovering from and living with neurological conditions, may reduce long term consequences such as limb contracture, skin…
- Trial name
- NCT05226637
- Testing
- ESWT (extra-corporeal shock wave therapy)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Aortic Diseases, Aorto-Iliac Atherosclerosis
Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access
The study will evaluate, in a controlled setting, the efficacy and safety of the intravascular lithotripsy using Shockwave™ M5+/L6 Peripheral Intravascular Lithotripsy Catheter to facilitate delivery of aortic large-bore devices…
- Conditions
- Aortic Diseases, Aorto-Iliac Atherosclerosis, Peripheral Arterial Disease
- Trial name
- SHOCK-ACCESS (NCT05880641)
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- EndoCore Lab s.r.l.
Sepsis, Trauma
Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults
Across the world, the most common cause of dying in the ICU is a disease called "sepsis". Sepsis is a disease in which the body's protective response to infection becomes too intense, unnecessarily damaging important organs in…
- Conditions
- Sepsis, Trauma, Shock, Acute Kidney Injury
- Trial name
- NCT01900275
- Testing
- Urine collection
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Denver Health and Hospital Authority
Urolithiasis
Music During ESWL for Entire Treatment
The aim of this study is to evaluate if music listening relieves pain and discomfort during Extracorporeal Shock-Waves Lithotripsy (ESWL).
- Trial name
- NCT04380675
- Testing
- Music
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Sepsis, Septic Shock
Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01)
Sepsis remains the leading cause of ICU admission in neutropenic patients. This condition remains associated with a high morbidity and mortality, with hospital mortality of 60% when vasopressors are required.
- Conditions
- Sepsis, Septic Shock, Hematologic Malignancy, Tumor
- Trial name
- NCT05443854
- Testing
- Aminoglycosides intervention, Lack of protective isolation intervention, No systematic aminoglycosides intervention - standard arm
- Volunteers
- 340 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Erectile Dysfunction
DualStim Therapy With or Without Umbilical Cord Derived Wharton's Jelly for Erectile Dysfunction
The purpose of this study is to determine the immediate and short-term efficacy of the methodological application of DualStim Therapy - Focused Extracorporeal Shock Wave Therapy (fESWT) and Radial Extracorporeal Shock Wave…
- Trial name
- NCT04424394
- Testing
- DualStim Therapy, Umbilical cord-derived Wharton's Jelly, Saline
- Volunteers
- 60 people
- Sponsor
- BioIntegrate
Shock, Peripheral Venous Catheterization
Pulse Study: Peripheral Use of Low-dose Vasopressors for Safety and Efficacy in the Intensive Care Unit
Using medications to increase blood pressure, called vasopressors, is invaluable in treating patients who have difficulty maintaining stable blood pressure.
- Conditions
- Shock, Peripheral Venous Catheterization, Central Venous Catheterization, Critically Ill Patients Admitted in ICU
- Trial name
- PULSE (NCT06920173)
- Testing
- Experiemental: Peripheral Venous Catheter
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Kingston Health Sciences Centre
Septic Shock
Septic Shock Management Guided by Ultrasound: SEPTICUS Trial
This clinical study aims to compare the recent septic shock management protocol from American College of Critical Care Medicine (ACCM) to Ultrasound-guided Septic Shock Management (USSM) protocol.
- Trial name
- NCT04728529
- Testing
- USSM protocol, ACCM protocol
- Where
- Indonesia
- Volunteers
- 340 people
- Sponsor
- Saptadi Yuliarto
Severe Sepsis With Septic Shock, Lactate
Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients
Using sodium lactate Ringer's injection resuscitate septic shock patients and Compared with other solution, in order to make clear whether can improve the prognosis.
- Trial name
- NCT02449928
- Testing
- sodium lactate Ringer's injection(Baxter, ShangHai, China), Compound Sodium Chloride Injection (CR Double-Crane, Beijing, China)
- Sponsor
- Peking Union Medical College Hospital
Shock Septic, Photoplethysmography
Types of Photoplethysmographic Waves in Adult Patients with Septic Shock
The objective of this study is to identify the types of Photoplethysmographic waves present in adults with septic shock and determine whether these waves correlate with other variables of tissue hypoperfusion such as capillary…
- Conditions
- Shock Septic, Photoplethysmography, Waveform
- Trial name
- SHOCK PLETH (NCT06786364)
- Where
- Mexico
- Volunteers
- 116 people
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Septic Shock, Sepsis
Vasopressor Use Improves Macrocirculation, But What Are Its Effects on Microcirculation?
To manage the treatment in the intensive care unit for patients with septic shock, central venous oxygen saturation (scvO2) is used as a macrocirculatory indicator, with a target value of 70% or higher being recommended.
- Conditions
- Septic Shock, Sepsis, Tissue Ischemia, Hemodynamic Instability
- Trial name
- NCT07312071
- Testing
- Vascular Occlusion Test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Acute Kidney Injury, Septic Shock
Does Urinary TIMP2 and IGFBP7 Can Identify High Risk Patients of Progression From Mild and Moderate to Severe Acute Kidney Injury During Septic Shock?
Septic shock is one of the leading causes of death in patients admitted to the intensive care unit (ICU). Acute kidney injury (AKI) occurs in almost 50% of septic patients and is associated with significant mortality.
- Trial name
- HEMOCHECK (NCT03547414)
- Testing
- Nephrocheck test
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Septic Shock, Inflammation
Pharmacology of Exenatide in Pediatric Sepsis
Pharmacology of Exenatide in Pediatric Sepsis, PEPS is a phase 1-2 research study that will examine drug safety, drug metabolism, drug action and preliminary drug clinical effects of four does of exenatide injected every 12 hours…
- Conditions
- Septic Shock, Inflammation, Glucose Homeostasis, Organ Dysfunction
- Trial name
- PEPS (NCT01573806)
- Testing
- Exenatide, Exenatide vehicle
- Where
- United States
- Sponsor
- Seattle Children's Hospital
Cerebral Palsy, Spasticity, Muscle
Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy
Spasticity is the most common motor disorder in cerebral palsy (CP). The objectives of his therapeutic approach include; reducing pain, ease of use of orthopedic aids, improving posture, minimizing contractures and deformity, and…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Extracorporeal Shock Wave Therapy
- Trial name
- NCT05702606
- Testing
- Radial extracorporeal shock wave therapy (rESWT)
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Fundacio Aspace Catalunya
Sepsis, Septic Shock
PRIME Sepsis Trial: Early Sepsis Detection in the Emergency Department Using Presepsin and Immature Granulocytes
Early identification and timely intervention for sepsis in the emergency department (ED) are critical for improving patient outcomes.
- Trial name
- NCT07822412
- Where
- Taiwan
- Volunteers
- 699 people
- Sponsor
- Chang Gung Memorial Hospital
ST Elevation Myocardial Infarction (STEMI) Patients
ST Elevation Myocardial Infarction Hemodynamic OutComes: Role of Non-Invasive Cardiac System (SHOCk-NICaS) Study
Proposed novel solution for high-risk heart disease Overall in-hospital mortality among ST elevation myocardial infarction (STEMI) patients is 3-4%, but >50% patients experiencing cardiogenic shock (CS) secondary to STEMI die in…
- Trial name
- SHOCk-NICaS (NCT04586764)
- Testing
- Non-Invasive Cardiac System
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Manitoba
Shock, Septic
Corticosteroid Therapy of Septic Shock - Corticus
The purpose of the study is to determine whether steroids decrease 28-day mortality in patients with septic shock.
- Trial name
- Corticus (NCT00147004)
- Testing
- hydrocortisone sodium succinate
- Where
- 57 sites in Austria, Belgium and 7 more
- Volunteers
- 500 people
- Sponsor
- Hadassah Medical Organization